STRINGSTRING
acacb acacb ATP6 ATP6 ATP8 ATP8 allc allc LOC102685429 LOC102685429 gnmt gnmt elovl4 elovl4 rab23 rab23 W5NK17_LEPOC W5NK17_LEPOC W5NJV3_LEPOC W5NJV3_LEPOC elovl5 elovl5 acss1 acss1 nme6 nme6 LOC102694194 LOC102694194 LOC102692797 LOC102692797 ada2 ada2 PDE7B PDE7B W5NGS9_LEPOC W5NGS9_LEPOC LOC102688344 LOC102688344 LOC102690679 LOC102690679 LOC102690478 LOC102690478 macrod2 macrod2 adcy3 adcy3 W5NG10_LEPOC W5NG10_LEPOC parp1 parp1 nudt5 nudt5 dhtkd1 dhtkd1 atp5f1c atp5f1c pgam2 pgam2 lrguk lrguk LOC102689444 LOC102689444 impdh1 impdh1 W5NE90_LEPOC W5NE90_LEPOC nudt18 nudt18 LOC102698058 LOC102698058 OGDH OGDH W5NDV2_LEPOC W5NDV2_LEPOC nudt4 nudt4 NT5DC4 NT5DC4 gck gck FAR2 FAR2 LOC102696574 LOC102696574 entpd4 entpd4 adpgk adpgk W5NCK6_LEPOC W5NCK6_LEPOC W5NCH1_LEPOC W5NCH1_LEPOC adal adal acsl4 acsl4 gucy2f gucy2f IMPDH IMPDH ppcdc ppcdc W5N9Y4_LEPOC W5N9Y4_LEPOC hddc3 hddc3 clpx clpx W5N9F8_LEPOC W5N9F8_LEPOC paics paics pgk1 pgk1 acsl1 acsl1 mcee mcee LOC102697601 LOC102697601 W5N7Q9_LEPOC W5N7Q9_LEPOC atp5mc1 atp5mc1 prpsap1 prpsap1 mtap mtap LOC102685925 LOC102685925 HTD2 HTD2 pdhb pdhb pde5a pde5a elovl2 elovl2 adcy1 adcy1 LOC102688707 LOC102688707 efl1 efl1 W5N557_LEPOC W5N557_LEPOC aadat aadat adss1 adss1 papss1 papss1 adcy8 adcy8 W5N4K7_LEPOC W5N4K7_LEPOC LOC102692279 LOC102692279 W5N3Y4_LEPOC W5N3Y4_LEPOC LOC102685602 LOC102685602 W5N3S1_LEPOC W5N3S1_LEPOC LOC102690536 LOC102690536 ampd2 ampd2 W5N3E5_LEPOC W5N3E5_LEPOC gpam gpam LOC102689386 LOC102689386 W5N372_LEPOC W5N372_LEPOC acsl5 acsl5 foxk2 foxk2 dcakd dcakd PANK3 PANK3 dmac2l dmac2l atp5md atp5md nt5c2 nt5c2 elovl6 elovl6 W5N106_LEPOC W5N106_LEPOC DCK DCK galk1 galk1 W5N065_LEPOC W5N065_LEPOC mccc2 mccc2 W5MZR7_LEPOC W5MZR7_LEPOC atp5pb atp5pb ak3 ak3 atp5f1a atp5f1a NME2 NME2 W5MYK5_LEPOC W5MYK5_LEPOC hmgcs1 hmgcs1 LOC102690807 LOC102690807 ndufs1 ndufs1 gart gart W5MXU9_LEPOC W5MXU9_LEPOC atp5pd atp5pd atp5pf atp5pf dlst dlst pfas pfas LOC102696239 LOC102696239 fhit fhit W5MWP5_LEPOC W5MWP5_LEPOC htr2a htr2a W5MWK3_LEPOC W5MWK3_LEPOC W5MWK0_LEPOC W5MWK0_LEPOC acsl6 acsl6 LOC102682246 LOC102682246 suclg2 suclg2 atic atic prps2 prps2 nudt3 nudt3 pfkl pfkl nme5 nme5 W5MU30_LEPOC W5MU30_LEPOC LOC102699211 LOC102699211 W5MTL6_LEPOC W5MTL6_LEPOC gda gda LOC102690218 LOC102690218 LOC102685413 LOC102685413 W5MSJ8_LEPOC W5MSJ8_LEPOC W5MSI7_LEPOC W5MSI7_LEPOC HK1 HK1 guk1 guk1 LOC102687955 LOC102687955 ENTPD7 ENTPD7 W5MQS5_LEPOC W5MQS5_LEPOC W5MPY2_LEPOC W5MPY2_LEPOC nme7 nme7 W5MPS8_LEPOC W5MPS8_LEPOC gcdh gcdh LOC102689735 LOC102689735 W5MNU7_LEPOC W5MNU7_LEPOC gucy1a1 gucy1a1 tdo2 tdo2 W5MND5_LEPOC W5MND5_LEPOC ATP5F1B ATP5F1B W5MMQ4_LEPOC W5MMQ4_LEPOC tpi1 tpi1 LOC102684890 LOC102684890 elovl7 elovl7 W5MLT0_LEPOC W5MLT0_LEPOC pde4d pde4d W5MLE4_LEPOC W5MLE4_LEPOC W5MKY0_LEPOC W5MKY0_LEPOC ola1 ola1 adcy7 adcy7 LOC102698052 LOC102698052 W5MK89_LEPOC W5MK89_LEPOC atp5mc3 atp5mc3 W5MJW1_LEPOC W5MJW1_LEPOC gucd1 gucd1 W5MJ55_LEPOC W5MJ55_LEPOC gapdh gapdh pde4b pde4b W5MJ10_LEPOC W5MJ10_LEPOC gucy1a2 gucy1a2 W5MIQ9_LEPOC W5MIQ9_LEPOC W5MIG3_LEPOC W5MIG3_LEPOC atp5po atp5po LOC102690233 LOC102690233 LOC102690023 LOC102690023 LOC102682268 LOC102682268 atp5f1e atp5f1e RAN RAN W5MGK4_LEPOC W5MGK4_LEPOC W5MG14_LEPOC W5MG14_LEPOC aldoc aldoc LOC102689087 LOC102689087 prpsap2 prpsap2 pde8b pde8b parg parg LOC102692626 LOC102692626 acss2 acss2 LOC107075561 LOC107075561 nppa nppa LOC102688208 LOC102688208 LOC102697981 LOC102697981 hmgcr hmgcr ACOT12 ACOT12 acot7 acot7 acaca acaca opa1 opa1 nudt2 nudt2 W5MBX6_LEPOC W5MBX6_LEPOC pipox pipox icmt icmt pde7a pde7a pank4 pank4 atp5mf atp5mf aprt aprt W5MAJ7_LEPOC W5MAJ7_LEPOC kdm1a kdm1a stoml2 stoml2 W5MA78_LEPOC W5MA78_LEPOC W5MA42_LEPOC W5MA42_LEPOC mvk mvk urad urad far1 far1 acsl3 acsl3 atp5mg atp5mg pde9a pde9a elovl1 elovl1 W5M8J6_LEPOC W5M8J6_LEPOC LOC102696292 LOC102696292 LOC102694050 LOC102694050 ampd3 ampd3 ak5 ak5 gapdhs gapdhs pdha1 pdha1 acot9 acot9 ctns ctns W5M6I3_LEPOC W5M6I3_LEPOC acot11 acot11 LOC102682188 LOC102682188 acot8 acot8 gmps gmps LOC102691887 LOC102691887 gmpr gmpr adcy9 adcy9 W5M400_LEPOC W5M400_LEPOC adcy5 adcy5 W5M3H3_LEPOC W5M3H3_LEPOC mrps34 mrps34 W5M2I6_LEPOC W5M2I6_LEPOC W5M2G8_LEPOC W5M2G8_LEPOC W5M2C2_LEPOC W5M2C2_LEPOC LOC102691117 LOC102691117 PANK2 PANK2 W5M225_LEPOC W5M225_LEPOC nt5c1a nt5c1a W5M1Q2_LEPOC W5M1Q2_LEPOC pde4c pde4c ada ada nudt19 nudt19 W5M0G9_LEPOC W5M0G9_LEPOC atp6v1b1 atp6v1b1 ppcs ppcs dlat dlat nudt1 nudt1 W5LZJ9_LEPOC W5LZJ9_LEPOC pdhx pdhx W5LZE9_LEPOC W5LZE9_LEPOC W5LZC8_LEPOC W5LZC8_LEPOC W5LZA1_LEPOC W5LZA1_LEPOC LOC107076242 LOC107076242 ak2 ak2 LOC102684193 LOC102684193 W5LXZ1_LEPOC W5LXZ1_LEPOC bpgm bpgm LOC102682727 LOC102682727 W5LXI0_LEPOC W5LXI0_LEPOC adcy2 adcy2 W5LWZ0_LEPOC W5LWZ0_LEPOC atp5f1d atp5f1d W5LVL2_LEPOC W5LVL2_LEPOC pank1 pank1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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acacbAcetyl-CoA carboxylase beta. (2385 aa)
ATP6ATP synthase subunit a. (227 aa)
ATP8ATP synthase protein 8. (55 aa)
allcAllantoicase. (363 aa)
LOC1026854295'-nucleotidase, cytosolic IB b. (368 aa)
gnmtGlycine N-methyltransferase. (296 aa)
elovl4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (368 aa)
rab23RAB23, member RAS oncogene family. (240 aa)
W5NK17_LEPOC5'-nucleotidase domain containing 1. (464 aa)
W5NJV3_LEPOC5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. (461 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (297 aa)
acss1Acetyl-coenzyme A synthetase. (697 aa)
nme6NDK domain-containing protein; Belongs to the NDK family. (185 aa)
LOC102694194Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
LOC102692797ADP-dependent glucokinase 2. (485 aa)
ada2Adenosine deaminase 2a. (515 aa)
PDE7BPhosphodiesterase. (492 aa)
W5NGS9_LEPOCLeucine-rich repeat kinase 2. (2389 aa)
LOC102688344Deoxyguanosine kinase. (275 aa)
LOC102690679Uncharacterized protein. (453 aa)
LOC102690478Uncharacterized protein. (431 aa)
macrod2Mono-ADP ribosylhydrolase 2. (468 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
W5NG10_LEPOCAminoadipate-semialdehyde synthase. (931 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1009 aa)
nudt5Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family. (220 aa)
dhtkd1Dehydrogenase E1 and transketolase domain containing 1. (930 aa)
atp5f1cATP synthase F1 subunit gamma. (469 aa)
pgam2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (256 aa)
lrgukLeucine-rich repeats and guanylate kinase domain containing. (846 aa)
LOC102689444Acyl-CoA synthetase long chain family member 2. (704 aa)
impdh1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (626 aa)
W5NE90_LEPOCAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (459 aa)
nudt18Nudix (nucleoside diphosphate linked moiety X)-type motif 18. (330 aa)
LOC102698058Hexokinase 2. (923 aa)
OGDHOxoglutarate dehydrogenase. (1003 aa)
W5NDV2_LEPOCPoly (ADP-ribose) glycohydrolase, like. (500 aa)
nudt4Nudix (nucleoside diphosphate linked moiety X)-type motif 4a. (186 aa)
NT5DC45'-nucleotidase domain containing 4. (538 aa)
gckPhosphotransferase. (478 aa)
FAR2Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
LOC102696574Hypoxanthine phosphoribosyltransferase 1. (316 aa)
entpd4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (622 aa)
adpgkADP-dependent glucokinase. (495 aa)
W5NCK6_LEPOCVacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (509 aa)
W5NCH1_LEPOCPhosphoribosyl pyrophosphate synthetase 1B. (178 aa)
adalAdenosine deaminase-like. (357 aa)
acsl4Acyl-CoA synthetase long chain family member 4a. (712 aa)
gucy2fGuanylate cyclase. (1111 aa)
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (537 aa)
ppcdcPhosphopantothenoylcysteine decarboxylase. (207 aa)
W5N9Y4_LEPOCTransforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
hddc3HD domain containing 3. (181 aa)
clpxCaseinolytic mitochondrial matrix peptidase chaperone subunit a. (628 aa)
W5N9F8_LEPOCAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (511 aa)
paicsAIRC domain-containing protein. (1010 aa)
pgk1Phosphoglycerate kinase. (420 aa)
acsl1Acyl-CoA synthetase long chain family member 1b. (699 aa)
mceeMethylmalonyl CoA epimerase. (167 aa)
LOC102697601Enolase 3, (beta, muscle). (457 aa)
W5N7Q9_LEPOCANF_receptor domain-containing protein. (564 aa)
atp5mc1ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (139 aa)
prpsap1Phosphoribosyl pyrophosphate synthetase associated protein 1. (369 aa)
mtapS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (284 aa)
LOC102685925Guanylate cyclase. (863 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (126 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
pde5aPhosphodiesterase. (889 aa)
elovl2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (297 aa)
adcy1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1122 aa)
LOC102688707Phosphodiesterase. (822 aa)
efl1Elongation factor like GTPase 1. (1143 aa)
W5N557_LEPOCUncharacterized protein. (98 aa)
aadatAminoadipate aminotransferase. (424 aa)
adss1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
papss13'-phosphoadenosine 5'-phosphosulfate synthase 1. (627 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1224 aa)
W5N4K7_LEPOCATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1126 aa)
LOC102692279Zgc:110540. (268 aa)
W5N3Y4_LEPOCCoA synthase. (397 aa)
LOC102685602Acyl-CoA thioesterase 21. (390 aa)
W5N3S1_LEPOCO-acyl-ADP-ribose deacylase 1. (161 aa)
LOC102690536Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (274 aa)
ampd2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (826 aa)
W5N3E5_LEPOCUncharacterized protein. (1200 aa)
gpamGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
LOC102689386Guanylate cyclase. (1077 aa)
W5N372_LEPOCATP synthase membrane subunit eb. (61 aa)
acsl5Acyl-CoA synthetase long chain family member 5. (728 aa)
foxk2Forkhead box K2. (623 aa)
dcakdDephospho-CoA kinase domain containing. (238 aa)
PANK3Pantothenate kinase 3. (370 aa)
dmac2lDistal membrane arm assembly complex 2 like. (200 aa)
atp5mdATP synthase membrane subunit DAPIT. (59 aa)
nt5c25'-nucleotidase, cytosolic IIb. (575 aa)
elovl6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (266 aa)
W5N106_LEPOCGuanylate cyclase. (971 aa)
DCKDeoxycytidine kinase. (263 aa)
galk1Galactokinase 1. (393 aa)
W5N065_LEPOCLyase_1 domain-containing protein. (114 aa)
mccc2Methylcrotonoyl-CoA carboxylase 2 (beta). (567 aa)
W5MZR7_LEPOCGTP binding protein 1, like. (668 aa)
atp5pbATP synthase peripheral stalk-membrane subunit b. (252 aa)
ak3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (228 aa)
atp5f1aATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (555 aa)
NME2Nucleoside diphosphate kinase. (155 aa)
W5MYK5_LEPOCGuanylate cyclase domain-containing protein. (637 aa)
hmgcs13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (519 aa)
LOC102690807Acetyl-coenzyme A synthetase. (686 aa)
ndufs1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (736 aa)
gartTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1029 aa)
W5MXU9_LEPOCATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (819 aa)
atp5pdATP synthase peripheral stalk subunit d. (130 aa)
atp5pfATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (110 aa)
dlstDihydrolipoamide S-succinyltransferase. (460 aa)
pfasPhosphoribosylformylglycinamidine synthase. (1333 aa)
LOC102696239Guanylate cyclase. (1060 aa)
fhitSi:ch211-63i20.3. (117 aa)
W5MWP5_LEPOCAMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (735 aa)
htr2a5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (469 aa)
W5MWK3_LEPOCNudix (nucleoside diphosphate linked moiety X)-type motif 15. (161 aa)
W5MWK0_LEPOCCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (657 aa)
acsl6Uncharacterized protein. (722 aa)
LOC102682246Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (296 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (438 aa)
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (606 aa)
prps2Phosphoribosyl pyrophosphate synthetase 2. (318 aa)
nudt3Nudix (nucleoside diphosphate linked moiety X)-type motif 3b. (180 aa)
pfklATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
nme5NME/NM23 family member 5; Belongs to the NDK family. (217 aa)
W5MU30_LEPOCUncharacterized protein. (453 aa)
LOC102699211Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (504 aa)
W5MTL6_LEPOCEnolase 4. (582 aa)
gdaGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (450 aa)
LOC102690218Si:ch211-198n5.11. (605 aa)
LOC102685413Guanylate cyclase 1, soluble, beta 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (661 aa)
W5MSJ8_LEPOCGuanylate cyclase domain-containing protein. (209 aa)
W5MSI7_LEPOCGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (115 aa)
HK1Hexokinase 1. (985 aa)
guk1Guanylate kinase 1b. (224 aa)
LOC102687955Hexokinase domain containing 1. (914 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (613 aa)
W5MQS5_LEPOCHydroxysteroid (17-beta) dehydrogenase 4. (756 aa)
W5MPY2_LEPOCMitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (133 aa)
nme7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (387 aa)
W5MPS8_LEPOCUncharacterized protein. (1633 aa)
gcdhGlutaryl-CoA dehydrogenase b. (440 aa)
LOC102689735Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (305 aa)
W5MNU7_LEPOCGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (176 aa)
gucy1a1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1187 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (405 aa)
W5MND5_LEPOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (354 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (527 aa)
W5MMQ4_LEPOCNudix (nucleoside diphosphate linked moiety X)-type motif 8. (211 aa)
tpi1Triosephosphate isomerase. (249 aa)
LOC102684890Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (637 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (290 aa)
W5MLT0_LEPOCUncharacterized protein. (147 aa)
pde4dPhosphodiesterase. (693 aa)
W5MLE4_LEPOCPhosphodiesterase. (677 aa)
W5MKY0_LEPOCAdenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1204 aa)
ola1Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (401 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
LOC102698052Enolase 2. (452 aa)
W5MK89_LEPOCATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (788 aa)
atp5mc3ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (140 aa)
W5MJW1_LEPOCEnolase 1a, (alpha). (437 aa)
gucd1Guanylyl cyclase domain containing 1. (258 aa)
W5MJ55_LEPOC3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (463 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
pde4bPhosphodiesterase. (740 aa)
W5MJ10_LEPOCGuanylate cyclase. (1071 aa)
gucy1a2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (717 aa)
W5MIQ9_LEPOCAdenylate kinase 4; Belongs to the adenylate kinase family. (230 aa)
W5MIG3_LEPOCUncharacterized protein. (177 aa)
atp5poATP synthase peripheral stalk subunit OSCP. (212 aa)
LOC102690233Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (304 aa)
LOC102690023Zgc:103559. (459 aa)
LOC102682268Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (297 aa)
atp5f1eATP synthase F1 subunit epsilon. (49 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (220 aa)
W5MGK4_LEPOC3'-phosphoadenosine 5'-phosphosulfate synthase 2b. (626 aa)
W5MG14_LEPOCSerine hydroxymethyltransferase 2 (mitochondrial). (504 aa)
aldocFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (365 aa)
LOC102689087Zgc:174895. (185 aa)
prpsap2Phosphoribosyl pyrophosphate synthetase-associated protein 2. (385 aa)
pde8bPhosphodiesterase. (873 aa)
pargPoly (ADP-ribose) glycohydrolase a. (954 aa)
LOC102692626Guanylate cyclase. (847 aa)
acss2Acyl-CoA synthetase short chain family member 2. (701 aa)
LOC107075561Natriuretic peptide B. (144 aa)
nppaUncharacterized protein. (150 aa)
LOC102688208Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (749 aa)
LOC102697981Lens intrinsic membrane protein 2.1. (173 aa)
hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
ACOT12Acyl-CoA thioesterase 12. (568 aa)
acot7Acyl-CoA thioesterase 7. (344 aa)
acacaAcetyl-CoA carboxylase alpha. (2356 aa)
opa1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1014 aa)
nudt2Nudix (nucleoside diphosphate linked moiety X)-type motif 2. (150 aa)
W5MBX6_LEPOCSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (489 aa)
pipoxPipecolic acid oxidase. (397 aa)
icmtProtein-S-isoprenylcysteine O-methyltransferase. (301 aa)
pde7aPhosphodiesterase. (486 aa)
pank4Pantothenate kinase 4; Belongs to the type II pantothenate kinase family. (770 aa)
atp5mfATP synthase membrane subunit f. (93 aa)
aprtAdenine phosphoribosyltransferase. (182 aa)
W5MAJ7_LEPOCPfkB domain-containing protein. (265 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (859 aa)
stoml2Stomatin (EPB72)-like 2. (362 aa)
W5MA78_LEPOCHD domain-containing protein. (411 aa)
W5MA42_LEPOCSAM domain and HD domain 1. (617 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (398 aa)
uradUreidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase. (165 aa)
far1Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (518 aa)
acsl3Acyl-CoA synthetase long chain family member 3b. (719 aa)
atp5mgATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (107 aa)
pde9aPhosphodiesterase. (583 aa)
elovl1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (313 aa)
W5M8J6_LEPOCGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (674 aa)
LOC102696292Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
LOC102694050Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (570 aa)
ampd3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (764 aa)
ak5Adenylate kinase 5; Belongs to the adenylate kinase family. (559 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (395 aa)
acot9Acyl-CoA thioesterase 9, tandem duplicate 2. (434 aa)
ctnsCystinosin, lysosomal cystine transporter. (373 aa)
W5M6I3_LEPOCPhosphoribosyl transferase domain containing 1. (227 aa)
acot11Acyl-CoA thioesterase 11a. (576 aa)
LOC102682188Nucleoside diphosphate kinase. (168 aa)
acot8Acyl-CoA thioesterase 8. (343 aa)
gmpsGuanine monophosphate synthase. (692 aa)
LOC102691887Elongation of very long chain fatty acids protein. (284 aa)
gmprGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (363 aa)
adcy9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1361 aa)
W5M400_LEPOCAcyl-CoA synthetase short chain family member 2 like. (661 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1192 aa)
W5M3H3_LEPOCGuanylate cyclase. (1043 aa)
mrps34Mitochondrial ribosomal protein S34. (217 aa)
W5M2I6_LEPOCNucleoside diphosphate kinase. (177 aa)
W5M2G8_LEPOCMalonyl-CoA decarboxylase. (465 aa)
W5M2C2_LEPOCPhosphodiesterase. (559 aa)
LOC102691117Phosphodiesterase. (582 aa)
PANK2Pantothenate kinase 2. (440 aa)
W5M225_LEPOCGlucose-6-phosphate isomerase; Belongs to the GPI family. (560 aa)
nt5c1a5'-nucleotidase, cytosolic IAa. (369 aa)
W5M1Q2_LEPOCFat storage inducing transmembrane protein 2. (259 aa)
pde4cPhosphodiesterase. (776 aa)
adaAdenosine deaminase. (363 aa)
nudt19Nudix (nucleoside diphosphate linked moiety X)-type motif 19. (397 aa)
W5M0G9_LEPOC5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (140 aa)
atp6v1b1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (523 aa)
ppcsPhosphopantothenoylcysteine synthetase. (330 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (637 aa)
nudt1Nudix (nucleoside diphosphate linked moiety X)-type motif 1. (157 aa)
W5LZJ9_LEPOCMono-ADP ribosylhydrolase 1. (182 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (496 aa)
W5LZE9_LEPOCUncharacterized protein. (85 aa)
W5LZC8_LEPOCAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (351 aa)
W5LZA1_LEPOCDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (409 aa)
LOC107076242PfkB domain-containing protein. (111 aa)
ak2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (235 aa)
LOC102684193Guanylate cyclase. (1109 aa)
W5LXZ1_LEPOCPurine nucleoside phosphorylase 5a. (233 aa)
bpgmPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (260 aa)
LOC102682727Acyl-CoA synthetase medium chain family member 3. (588 aa)
W5LXI0_LEPOCBAAT_C domain-containing protein. (217 aa)
adcy2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1136 aa)
W5LWZ0_LEPOCAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (396 aa)
atp5f1dATP synthase F1 subunit delta. (161 aa)
W5LVL2_LEPOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (160 aa)
pank1Pantothenate kinase 1b. (450 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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