48 items (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ncf1	Neutrophil cytosolic factor 1. (473 aa)
	cat	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	LOC102698806	Zgc:73226. (182 aa)
	LOC102687462	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (188 aa)
	noxa1	Uncharacterized protein. (587 aa)
	ncf2	Neutrophil cytosolic factor 2. (505 aa)
	W5M6X7_LEPOC	Peroxiredoxin 4. (260 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (177 aa)
	ccn1	Cellular communication network factor 1. (377 aa)
	PXDNL	Peroxidasin like. (1493 aa)
	prdx1	Peroxiredoxin 1. (204 aa)
	ndufs3	NADH:ubiquinone oxidoreductase core subunit S3. (224 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (581 aa)
	ndufs4	NADH:ubiquinone oxidoreductase subunit S4. (170 aa)
	W5MJD1_LEPOC	Uncharacterized protein. (155 aa)
	NOX4	NADPH oxidase 4. (572 aa)
	LOC102686980	Myeloid-specific peroxidase. (761 aa)
	bnip3	BCL2 interacting protein 3. (198 aa)
	prdx2	Peroxiredoxin 2. (198 aa)
	noxo1	NADPH oxidase organizer 1b. (489 aa)
	sod1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	W5MSG4_LEPOC	FA complementation group C. (563 aa)
	gbf1	Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1876 aa)
	nrros	Negative regulator of reactive oxygen species. (690 aa)
	prdx3	Peroxiredoxin 3. (251 aa)
	rfk	Riboflavin kinase. (160 aa)
	TAFA4	TAFA chemokine like family member 4. (135 aa)
	inava	Innate immunity activator a. (600 aa)
	sh3pxd2b	SH3 and PX domains 2B. (915 aa)
	ndufs1	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (736 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (268 aa)
	ncf4	Neutrophil cytosolic factor 4. (352 aa)
	sh3pxd2a	SH3 and PX domains 2Aa. (1107 aa)
	nnt	Nicotinamide nucleotide transhydrogenase. (1086 aa)
	bcl2	BCL2 apoptosis regulator b. (231 aa)
	LOC102683994	Nicotinamide nucleotide transhydrogenase 2. (1080 aa)
	DUOX2	Dual oxidase 2. (1557 aa)
	duoxa2	Dual oxidase 2. (332 aa)
	W5N9C3_LEPOC	NADPH oxidase, EF-hand calcium binding domain 5. (777 aa)
	W5NDM5_LEPOC	Uncharacterized protein. (740 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (598 aa)
	W5NGS9_LEPOC	Leucine-rich repeat kinase 2. (2389 aa)
	sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
	TPO	Thyroid peroxidase. (735 aa)
	CYB5R4	Cytochrome b5 reductase 4. (523 aa)
	ccn2	Cellular communication network factor 2a. (353 aa)
	W5NKX8_LEPOC	Peroxidasin. (1498 aa)
	W5NNF4_LEPOC	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (214 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYB5R4	cat	ENSLOCP00000020462	ENSLOCP00000001160	Cytochrome b5 reductase 4.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.429
CYB5R4	rfk	ENSLOCP00000020462	ENSLOCP00000012004	Cytochrome b5 reductase 4.	Riboflavin kinase.	0.752
CYB5R4	sod2	ENSLOCP00000020462	ENSLOCP00000019955	Cytochrome b5 reductase 4.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.646
DUOX2	LOC102687462	ENSLOCP00000016944	ENSLOCP00000001426	Dual oxidase 2.	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	0.907
DUOX2	NOX4	ENSLOCP00000016944	ENSLOCP00000008728	Dual oxidase 2.	NADPH oxidase 4.	0.788
DUOX2	duoxa2	ENSLOCP00000016944	ENSLOCP00000016954	Dual oxidase 2.	Dual oxidase 2.	0.986
DUOX2	ncf1	ENSLOCP00000016944	ENSLOCP00000002206	Dual oxidase 2.	Neutrophil cytosolic factor 1.	0.896
DUOX2	ncf2	ENSLOCP00000016944	ENSLOCP00000002303	Dual oxidase 2.	Neutrophil cytosolic factor 2.	0.836
DUOX2	ncf4	ENSLOCP00000016944	ENSLOCP00000014067	Dual oxidase 2.	Neutrophil cytosolic factor 4.	0.890
DUOX2	noxa1	ENSLOCP00000016944	ENSLOCP00000002164	Dual oxidase 2.	Uncharacterized protein.	0.784
DUOX2	noxo1	ENSLOCP00000016944	ENSLOCP00000010760	Dual oxidase 2.	NADPH oxidase organizer 1b.	0.662
DUOX2	sh3pxd2a	ENSLOCP00000016944	ENSLOCP00000014709	Dual oxidase 2.	SH3 and PX domains 2Aa.	0.435
DUOX2	sh3pxd2b	ENSLOCP00000016944	ENSLOCP00000013191	Dual oxidase 2.	SH3 and PX domains 2B.	0.435
LOC102683994	W5NNF4_LEPOC	ENSLOCP00000016192	ENSLOCP00000022163	Nicotinamide nucleotide transhydrogenase 2.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.450
LOC102683994	cat	ENSLOCP00000016192	ENSLOCP00000001160	Nicotinamide nucleotide transhydrogenase 2.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.823
LOC102683994	nnt	ENSLOCP00000016192	ENSLOCP00000015121	Nicotinamide nucleotide transhydrogenase 2.	Nicotinamide nucleotide transhydrogenase.	0.857
LOC102683994	sod1	ENSLOCP00000016192	ENSLOCP00000011159	Nicotinamide nucleotide transhydrogenase 2.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.450
LOC102683994	sod2	ENSLOCP00000016192	ENSLOCP00000019955	Nicotinamide nucleotide transhydrogenase 2.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.649
LOC102686980	cat	ENSLOCP00000008738	ENSLOCP00000001160	Myeloid-specific peroxidase.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.517
LOC102687462	DUOX2	ENSLOCP00000001426	ENSLOCP00000016944	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Dual oxidase 2.	0.907