STRINGSTRING
LOC102689288 LOC102689288 W5M1C2_LEPOC W5M1C2_LEPOC lig3 lig3 yars1 yars1 rpl8 rpl8 ybx1 ybx1 mrps12 mrps12 ttc14 ttc14 HELZ2 HELZ2 rps28 rps28 rpa2 rpa2 lin28a lin28a nars1 nars1 eif1ax eif1ax W5M7Z3_LEPOC W5M7Z3_LEPOC kars1 kars1 mrps17 mrps17 rmi2 rmi2 spout1 spout1 nabp2 nabp2 dis3l2 dis3l2 psmc4 psmc4 meiob meiob W5MCR9_LEPOC W5MCR9_LEPOC zcchc17 zcchc17 W5MDX6_LEPOC W5MDX6_LEPOC supt6h supt6h W5MF22_LEPOC W5MF22_LEPOC ddias ddias mcm4 mcm4 SPIDR SPIDR psmc3 psmc3 rpa1 rpa1 carhsp1 carhsp1 W5MIR9_LEPOC W5MIR9_LEPOC eif5a2 eif5a2 W5MNK3_LEPOC W5MNK3_LEPOC W5MR27_LEPOC W5MR27_LEPOC polr2h polr2h W5MRH9_LEPOC W5MRH9_LEPOC dars2 dars2 ccar1 ccar1 CSDE1 CSDE1 rpa3 rpa3 dis3 dis3 mcm6 mcm6 exosc3 exosc3 polr3h polr3h W5N0X9_LEPOC W5N0X9_LEPOC W5N1N1_LEPOC W5N1N1_LEPOC stn1 stn1 psmc5 psmc5 psmc6 psmc6 dhx8 dhx8 LOC102697986 LOC102697986 aimp1 aimp1 mcm7 mcm7 rps23 rps23 LOC102695737 LOC102695737 mcm2 mcm2 LOC102684218 LOC102684218 EIF5AL1 EIF5AL1 YBX2 YBX2 dis3l dis3l LOC102697928 LOC102697928 eif2s1 eif2s1 ruvbl1 ruvbl1 W5NC42_LEPOC W5NC42_LEPOC PNPT1 PNPT1 mcm10 mcm10 W5NFW0_LEPOC W5NFW0_LEPOC mrpl2 mrpl2 W5NG96_LEPOC W5NG96_LEPOC psmc2 psmc2 SRBD1 SRBD1 mcm8 mcm8 lin28b lin28b W5NJ63_LEPOC W5NJ63_LEPOC rngtt rngtt W5NKI1_LEPOC W5NKI1_LEPOC mcm9 mcm9 dars1 dars1 W5M103_LEPOC W5M103_LEPOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102689288Uncharacterized protein. (2846 aa)
W5M1C2_LEPOCEukaryotic translation initiation factor 1A domain containing. (185 aa)
lig3DNA ligase. (1001 aa)
yars1Tyrosine--tRNA ligase. (528 aa)
rpl8Ribosomal protein L8. (257 aa)
ybx1Y box binding protein 1. (311 aa)
mrps12Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (145 aa)
ttc14Tetratricopeptide repeat domain 14. (757 aa)
HELZ2Helicase with zinc finger 2. (2849 aa)
rps28Ribosomal protein S28. (82 aa)
rpa2Replication protein A2. (277 aa)
lin28aLin-28 homolog A (C. elegans). (203 aa)
nars1Asparaginyl-tRNA synthetase. (561 aa)
eif1axEukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (152 aa)
W5M7Z3_LEPOCExosome component 1. (159 aa)
kars1Lysine--tRNA ligase. (581 aa)
mrps17Mitochondrial ribosomal protein S17. (143 aa)
rmi2RecQ mediated genome instability 2. (154 aa)
spout1SPOUT domain containing methyltransferase 1. (378 aa)
nabp2Nucleic acid binding protein 2. (206 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1009 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
W5MCR9_LEPOCNucleic acid binding protein 1a. (223 aa)
zcchc17Zinc finger, CCHC domain containing 17. (259 aa)
W5MDX6_LEPOCC-abl oncogene 1, non-receptor tyrosine kinase. (1408 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1288 aa)
W5MF22_LEPOCAsparaginyl-tRNA synthetase 2, mitochondrial. (492 aa)
ddiasUncharacterized protein. (172 aa)
mcm4DNA helicase; Belongs to the MCM family. (678 aa)
SPIDRScaffold protein involved in DNA repair. (961 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (443 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
carhsp1Calcium regulated heat stable protein 1. (167 aa)
W5MIR9_LEPOCSi:dkey-159f12.2. (110 aa)
eif5a2Eukaryotic translation initiation factor 5A. (159 aa)
W5MNK3_LEPOCTower domain-containing protein. (871 aa)
W5MR27_LEPOCDNA ligase. (924 aa)
polr2hInfo polymerase (RNA) II (DNA directed) polypeptide H. (112 aa)
W5MRH9_LEPOCProteasome 26S subunit, ATPase 1a; Belongs to the AAA ATPase family. (441 aa)
dars2Aspartyl-tRNA synthetase 2, mitochondrial. (661 aa)
ccar1Cell division cycle and apoptosis regulator 1. (1242 aa)
CSDE1Cold shock domain containing E1. (900 aa)
rpa3Replication protein A3. (121 aa)
dis3DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (951 aa)
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
exosc3Exosome component 3. (258 aa)
polr3hPolymerase (RNA) III (DNA directed) polypeptide H. (235 aa)
W5N0X9_LEPOCCold shock domain containing C2, RNA binding a. (83 aa)
W5N1N1_LEPOCProgrammed cell death 11. (1798 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (377 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (404 aa)
dhx8DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1203 aa)
LOC102697986DNA helicase; Belongs to the MCM family. (814 aa)
aimp1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1a. (349 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa)
rps23Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
LOC102695737DNA helicase; Belongs to the MCM family. (834 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
LOC102684218Lysine--tRNA ligase. (551 aa)
EIF5AL1Eukaryotic translation initiation factor 5A. (157 aa)
YBX2Y-box binding protein 2. (340 aa)
dis3lDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1048 aa)
LOC102697928Si:ch73-71d17.2. (834 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha a. (316 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (270 aa)
W5NC42_LEPOCRPA1 related single stranded DNA binding protein. (851 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (796 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (867 aa)
W5NFW0_LEPOCProtection of telomeres 1 homolog. (774 aa)
mrpl2Mitochondrial ribosomal protein L2. (326 aa)
W5NG96_LEPOCDNA helicase; Belongs to the MCM family. (815 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
SRBD1S1 RNA binding domain 1. (1000 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (852 aa)
lin28bLin-28 homolog B (C. elegans). (247 aa)
W5NJ63_LEPOCUncharacterized protein. (1390 aa)
rngttPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (605 aa)
W5NKI1_LEPOCSingle-stranded DNA binding protein 1. (76 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (660 aa)
dars1Aspartyl-tRNA synthetase. (534 aa)
W5M103_LEPOCDNA ligase. (1030 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.