(28 nodes) Protein kinase, C-terminal network (Lepisosteus oculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5LZM9_LEPOC	Non-specific serine/threonine protein kinase. (369 aa)
	rps6ka3	Ribosomal protein S6 kinase. (720 aa)
	akt2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (714 aa)
	CDC42BPA	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1720 aa)
	SGK1	Non-specific serine/threonine protein kinase. (597 aa)
	prkce	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (743 aa)
	LOC102686641	Ribosomal protein S6 kinase. (735 aa)
	LOC102691934	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
	W5MB47_LEPOC	Non-specific serine/threonine protein kinase. (491 aa)
	W5MCL1_LEPOC	Protein kinase N2. (977 aa)
	W5MDV9_LEPOC	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
	rps6ka1	Ribosomal protein S6 kinase. (753 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
	W5MG04_LEPOC	Protein kinase N3. (936 aa)
	W5MHX4_LEPOC	Protein kinase N1b. (927 aa)
	W5MJN0_LEPOC	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (492 aa)
	prkci	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
	W5MVK0_LEPOC	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (713 aa)
	stk38	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
	prkca	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (580 aa)
	W5N9G8_LEPOC	Ribosomal protein S6 kinase. (782 aa)
	prkcd	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
	rps6kb1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (508 aa)
	LOC102691210	Ribosomal protein S6 kinase. (740 aa)
	STK38L	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (464 aa)
	W5NE85_LEPOC	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (469 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42BPA	W5MB47_LEPOC	ENSLOCP00000019739	ENSLOCP00000005606	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Non-specific serine/threonine protein kinase.	0.488
CDC42BPA	W5MCL1_LEPOC	ENSLOCP00000019739	ENSLOCP00000006120	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Protein kinase N2.	0.432
CDC42BPA	W5MG04_LEPOC	ENSLOCP00000019739	ENSLOCP00000007313	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Protein kinase N3.	0.432
CDC42BPA	W5MHX4_LEPOC	ENSLOCP00000019739	ENSLOCP00000007983	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Protein kinase N1b.	0.432
LOC102686641	W5MB47_LEPOC	ENSLOCP00000020793	ENSLOCP00000005606	Ribosomal protein S6 kinase.	Non-specific serine/threonine protein kinase.	0.440
LOC102686641	rps6ka1	ENSLOCP00000020793	ENSLOCP00000006596	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.477
LOC102691210	W5MB47_LEPOC	ENSLOCP00000018514	ENSLOCP00000005606	Ribosomal protein S6 kinase.	Non-specific serine/threonine protein kinase.	0.440
LOC102691210	rps6ka1	ENSLOCP00000018514	ENSLOCP00000006596	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.729
LOC102691934	SGK1	ENSLOCP00000005110	ENSLOCP00000020006	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.858
LOC102691934	STK38L	ENSLOCP00000005110	ENSLOCP00000018733	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.594
LOC102691934	W5LZM9_LEPOC	ENSLOCP00000005110	ENSLOCP00000001586	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.851
LOC102691934	W5MB47_LEPOC	ENSLOCP00000005110	ENSLOCP00000005606	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.745
LOC102691934	W5NE85_LEPOC	ENSLOCP00000005110	ENSLOCP00000018944	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.670
LOC102691934	akt1	ENSLOCP00000005110	ENSLOCP00000015716	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.669
LOC102691934	akt2	ENSLOCP00000005110	ENSLOCP00000018064	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.669
LOC102691934	stk38	ENSLOCP00000005110	ENSLOCP00000014157	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.594
SGK1	LOC102691934	ENSLOCP00000020006	ENSLOCP00000005110	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.858
SGK1	STK38L	ENSLOCP00000020006	ENSLOCP00000018733	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.594
SGK1	W5LZM9_LEPOC	ENSLOCP00000020006	ENSLOCP00000001586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.840
SGK1	W5MB47_LEPOC	ENSLOCP00000020006	ENSLOCP00000005606	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.850