(29 nodes) PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily network (Lepisosteus oculatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	PLCXD1	Phosphatidylinositol specific phospholipase C X domain containing 1. (325 aa)
	LOC102696192	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1308 aa)
	LOC102696153	Si:dkey-152b24.6. (313 aa)
	plcd4	Phosphoinositide phospholipase C. (770 aa)
	W5MU43_LEPOC	Phosphoinositide phospholipase C. (781 aa)
	plcd3	Phosphoinositide phospholipase C. (778 aa)
	LOC102695488	Phosphoinositide phospholipase C. (1132 aa)
	W5LVD8_LEPOC	PLCXc domain-containing protein. (269 aa)
	W5LY81_LEPOC	Glycerophosphodiester phosphodiesterase domain containing 5b. (624 aa)
	W5LZ25_LEPOC	Glycerophosphodiester phosphodiesterase domain containing 1. (316 aa)
	plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1274 aa)
	gde1	Glycerophosphodiester phosphodiesterase 1. (346 aa)
	W5M5N6_LEPOC	Phosphoinositide phospholipase C. (1705 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1285 aa)
	plce1	Phospholipase C, epsilon 1. (2331 aa)
	W5MEN6_LEPOC	Phosphoinositide phospholipase C. (1409 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1295 aa)
	plcl1	Phosphoinositide phospholipase C. (884 aa)
	LOC102682829	Phosphatidylinositol-specific phospholipase C, X domain containing 2. (296 aa)
	gdpd2	Glycerophosphodiester phosphodiesterase domain containing 2. (568 aa)
	PLCZ1	Phosphoinositide phospholipase C. (597 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1190 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
	gpcpd1	Glycerophosphocholine phosphodiesterase 1. (673 aa)
	plcxd3	Phosphatidylinositol-specific phospholipase C, X domain containing 3. (322 aa)
	GDPD4	Glycerophosphodiester phosphodiesterase domain containing 4a. (606 aa)
	plcl2	Phosphoinositide phospholipase C. (1109 aa)
	plcxd1	Si:dkey-66a8.7. (316 aa)
	LOC102693777	Phosphatidylinositol-specific phospholipase C, X domain containing 1. (331 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GDPD4	gpcpd1	ENSLOCP00000007972	ENSLOCP00000020334	Glycerophosphodiester phosphodiesterase domain containing 4a.	Glycerophosphocholine phosphodiesterase 1.	0.630
LOC102693777	W5MEN6_LEPOC	ENSLOCP00000009799	ENSLOCP00000006845	Phosphatidylinositol-specific phospholipase C, X domain containing 1.	Phosphoinositide phospholipase C.	0.434
LOC102695488	LOC102696192	ENSLOCP00000015450	ENSLOCP00000010403	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.425
LOC102695488	PLCB1	ENSLOCP00000015450	ENSLOCP00000020301	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.561
LOC102695488	PLCB2	ENSLOCP00000015450	ENSLOCP00000015843	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.561
LOC102695488	PLCB4	ENSLOCP00000015450	ENSLOCP00000020300	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.496
LOC102695488	W5MEN6_LEPOC	ENSLOCP00000015450	ENSLOCP00000006845	Phosphoinositide phospholipase C.	Phosphoinositide phospholipase C.	0.483
LOC102695488	plcg1	ENSLOCP00000015450	ENSLOCP00000005492	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.425
LOC102695488	plcg2	ENSLOCP00000015450	ENSLOCP00000003143	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.425
LOC102696153	W5LVD8_LEPOC	ENSLOCP00000010845	ENSLOCP00000000095	Si:dkey-152b24.6.	PLCXc domain-containing protein.	0.573
LOC102696192	LOC102695488	ENSLOCP00000010403	ENSLOCP00000015450	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide phospholipase C.	0.425
LOC102696192	PLCB1	ENSLOCP00000010403	ENSLOCP00000020301	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.862
LOC102696192	PLCB2	ENSLOCP00000010403	ENSLOCP00000015843	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.845
LOC102696192	PLCB4	ENSLOCP00000010403	ENSLOCP00000020300	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.858
LOC102696192	PLCZ1	ENSLOCP00000010403	ENSLOCP00000018988	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide phospholipase C.	0.540
LOC102696192	W5M5N6_LEPOC	ENSLOCP00000010403	ENSLOCP00000003694	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide phospholipase C.	0.575
LOC102696192	W5MEN6_LEPOC	ENSLOCP00000010403	ENSLOCP00000006845	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide phospholipase C.	0.575
LOC102696192	W5MU43_LEPOC	ENSLOCP00000010403	ENSLOCP00000011902	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide phospholipase C.	0.859
LOC102696192	plcd3	ENSLOCP00000010403	ENSLOCP00000014163	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide phospholipase C.	0.860
LOC102696192	plcd4	ENSLOCP00000010403	ENSLOCP00000010902	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide phospholipase C.	0.859