STRINGSTRING
W5LVL5_LEPOC W5LVL5_LEPOC W5LVS5_LEPOC W5LVS5_LEPOC W5LW14_LEPOC W5LW14_LEPOC W5LWD2_LEPOC W5LWD2_LEPOC LOC102696687 LOC102696687 W5LWP3_LEPOC W5LWP3_LEPOC W5LWU1_LEPOC W5LWU1_LEPOC W5LX14_LEPOC W5LX14_LEPOC W5LXJ3_LEPOC W5LXJ3_LEPOC rfc4 rfc4 rfc2 rfc2 W5LZH0_LEPOC W5LZH0_LEPOC RTEL1 RTEL1 W5M103_LEPOC W5M103_LEPOC pola1 pola1 pold3 pold3 chtf8 chtf8 W5M3C4_LEPOC W5M3C4_LEPOC ruvbl2 ruvbl2 W5M4G9_LEPOC W5M4G9_LEPOC W5M4I8_LEPOC W5M4I8_LEPOC ccna2 ccna2 rpa2 rpa2 W5M5Q6_LEPOC W5M5Q6_LEPOC W5M5U5_LEPOC W5M5U5_LEPOC rfc5 rfc5 W5M709_LEPOC W5M709_LEPOC terf1 terf1 W5M8C8_LEPOC W5M8C8_LEPOC CDK2 CDK2 pif1 pif1 W5M9S6_LEPOC W5M9S6_LEPOC W5MAW9_LEPOC W5MAW9_LEPOC ppp6c ppp6c meiob meiob chtf18 chtf18 ankrd28 ankrd28 rpa1 rpa1 LOC107080026 LOC107080026 W5MJK0_LEPOC W5MJK0_LEPOC prim1 prim1 recql4 recql4 rfc3 rfc3 W5MPI1_LEPOC W5MPI1_LEPOC LOC102685849 LOC102685849 dscc1 dscc1 W5MSA1_LEPOC W5MSA1_LEPOC DNA2 DNA2 nhp2 nhp2 shq1 shq1 W5MXW8_LEPOC W5MXW8_LEPOC rpa3 rpa3 H2AZ1 H2AZ1 GAR1 GAR1 stn1 stn1 trub1 trub1 rfc1 rfc1 exd2 exd2 terf2ip terf2ip W5N7F3_LEPOC W5N7F3_LEPOC W5N7V0_LEPOC W5N7V0_LEPOC W5N7V5_LEPOC W5N7V5_LEPOC atrx atrx W5LVJ9_LEPOC W5LVJ9_LEPOC W5N8G8_LEPOC W5N8G8_LEPOC W5N963_LEPOC W5N963_LEPOC blm blm pold2 pold2 W5NDT6_LEPOC W5NDT6_LEPOC pcna pcna W5NFW0_LEPOC W5NFW0_LEPOC ANKRD66 ANKRD66 prim2 prim2 W5NLL5_LEPOC W5NLL5_LEPOC LOC102699233 LOC102699233 LOC102686492 LOC102686492 LOC102694187 LOC102694187
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5LVL5_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (858 aa)
W5LVS5_LEPOCUncharacterized protein. (134 aa)
W5LW14_LEPOCHelitron_like_N domain-containing protein. (390 aa)
W5LWD2_LEPOCHELICc2 domain-containing protein. (80 aa)
LOC102696687Uncharacterized protein. (121 aa)
W5LWP3_LEPOCUncharacterized protein. (178 aa)
W5LWU1_LEPOCHELICc2 domain-containing protein. (158 aa)
W5LX14_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (792 aa)
W5LXJ3_LEPOCDNA_pol_B domain-containing protein. (97 aa)
rfc4Replication factor C (activator 1) 4. (359 aa)
rfc2Replication factor C (activator 1) 2. (358 aa)
W5LZH0_LEPOCHTH myb-type domain-containing protein. (575 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1117 aa)
W5M103_LEPOCDNA ligase. (1030 aa)
pola1DNA polymerase. (1486 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (125 aa)
W5M3C4_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (333 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
W5M4G9_LEPOCDNA_pol_E_B domain-containing protein. (66 aa)
W5M4I8_LEPOCUncharacterized protein. (168 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (434 aa)
rpa2Replication protein A2. (277 aa)
W5M5Q6_LEPOCUncharacterized protein. (209 aa)
W5M5U5_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (263 aa)
rfc5Replication factor C (activator 1) 5. (367 aa)
W5M709_LEPOCTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1056 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (400 aa)
W5M8C8_LEPOCAnkyrin repeat domain 44. (475 aa)
CDK2Cyclin dependent kinase 2. (252 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (659 aa)
W5M9S6_LEPOCXPGI domain-containing protein. (345 aa)
W5MAW9_LEPOCAnkyrin repeat domain 52a. (1073 aa)
ppp6cSerine/threonine-protein phosphatase. (306 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (837 aa)
ankrd28Ankyrin repeat domain 28b. (1085 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
LOC107080026Uncharacterized protein. (628 aa)
W5MJK0_LEPOCHistone H2B; Belongs to the histone H2B family. (136 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa)
recql4RecQ helicase-like 4. (1459 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
W5MPI1_LEPOCCyclin A1; Belongs to the cyclin family. (401 aa)
LOC102685849Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
dscc1DNA replication and sister chromatid cohesion 1. (391 aa)
W5MSA1_LEPOCRegulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (613 aa)
DNA2DNA replication helicase/nuclease 2. (1397 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (154 aa)
shq1SHQ1, H/ACA ribonucleoprotein assembly factor. (626 aa)
W5MXW8_LEPOCWRN RecQ like helicase. (1464 aa)
rpa3Replication protein A3. (121 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
GAR1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (234 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (377 aa)
trub1TruB pseudouridine (psi) synthase family member 1. (293 aa)
rfc1Replication factor C subunit 1. (1204 aa)
exd2Exonuclease 3'-5' domain containing 2. (613 aa)
terf2ipUncharacterized protein. (384 aa)
W5N7F3_LEPOCWD repeat containing, antisense to TP53. (422 aa)
W5N7V0_LEPOCUncharacterized protein. (579 aa)
W5N7V5_LEPOCUncharacterized protein. (157 aa)
atrxATRX chromatin remodeler, like. (2427 aa)
W5LVJ9_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (461 aa)
W5N8G8_LEPOCDyskeratosis congenita 1, dyskerin. (538 aa)
W5N963_LEPOCUncharacterized protein. (205 aa)
blmBLM RecQ like helicase. (1481 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
W5NDT6_LEPOCHistone H2A; Belongs to the histone H2A family. (129 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
W5NFW0_LEPOCProtection of telomeres 1 homolog. (774 aa)
ANKRD66Ankyrin repeat domain 66. (160 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (512 aa)
W5NLL5_LEPOCHistone H2B; Belongs to the histone H2B family. (115 aa)
LOC102699233Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102686492Histone H2A; Belongs to the histone H2A family. (141 aa)
LOC102694187Histone H2A; Belongs to the histone H2A family. (142 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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