STRINGSTRING
wnt3 wnt3 LOC102683700 LOC102683700 W5LW40_LEPOC W5LW40_LEPOC W5LWJ3_LEPOC W5LWJ3_LEPOC W5LXB1_LEPOC W5LXB1_LEPOC W5LXB6_LEPOC W5LXB6_LEPOC W5LXB8_LEPOC W5LXB8_LEPOC psmb2 psmb2 W5LXK8_LEPOC W5LXK8_LEPOC W5LXQ3_LEPOC W5LXQ3_LEPOC W5LXX5_LEPOC W5LXX5_LEPOC W5LYH4_LEPOC W5LYH4_LEPOC W5LZH3_LEPOC W5LZH3_LEPOC ctnnb1 ctnnb1 sox8 sox8 men1 men1 uba52 uba52 csnk2a1 csnk2a1 psmd13 psmd13 lrp5 lrp5 crebbp crebbp W5M4V5_LEPOC W5M4V5_LEPOC RNF43 RNF43 sox6 sox6 rspo2 rspo2 kremen1 kremen1 znrf3 znrf3 psma1 psma1 psmd5 psmd5 W5M709_LEPOC W5M709_LEPOC LOC102684155 LOC102684155 csnk2a2 csnk2a2 PSMA7 PSMA7 cul3 cul3 psmd7 psmd7 zbtb44 zbtb44 W5M9W8_LEPOC W5M9W8_LEPOC W5M9Z0_LEPOC W5M9Z0_LEPOC LOC102697712 LOC102697712 psmd1 psmd1 psmc4 psmc4 psmb7 psmb7 psmd9 psmd9 wnt8b wnt8b sox18 sox18 ryk ryk sox17 sox17 W5MFN8_LEPOC W5MFN8_LEPOC TNKS2 TNKS2 psmc3 psmc3 SLC39A13 SLC39A13 dkk1 dkk1 psma8 psma8 W5MH26_LEPOC W5MH26_LEPOC tle5 tle5 lgr4 lgr4 ctnnbip1 ctnnbip1 bcl9 bcl9 gsk3b gsk3b W5MJH0_LEPOC W5MJH0_LEPOC W5MJK0_LEPOC W5MJK0_LEPOC fzd4 fzd4 LOC102684075 LOC102684075 cdc73 cdc73 psmf1 psmf1 rspo4 rspo4 wnt1 wnt1 W5MM76_LEPOC W5MM76_LEPOC smarca4 smarca4 W5MP85_LEPOC W5MP85_LEPOC sfrp2 sfrp2 psmd14 psmd14 W5MQE4_LEPOC W5MQE4_LEPOC sfrp5 sfrp5 W5MRH9_LEPOC W5MRH9_LEPOC psma6 psma6 wnt3a wnt3a W5MSG6_LEPOC W5MSG6_LEPOC W5MSH6_LEPOC W5MSH6_LEPOC psma2 psma2 dact1 dact1 psma3 psma3 pip5k1b pip5k1b W5MTD3_LEPOC W5MTD3_LEPOC LGR6 LGR6 W5MUA3_LEPOC W5MUA3_LEPOC TLE4 TLE4 tle1 tle1 KLHL12 KLHL12 ppp2r5e ppp2r5e PPP2CA PPP2CA W5MVZ9_LEPOC W5MVZ9_LEPOC psmd6 psmd6 apc apc W5MX40_LEPOC W5MX40_LEPOC cav3 cav3 hecw1 hecw1 ppp2cb ppp2cb hmgxb3 hmgxb3 H2AZ1 H2AZ1 rbbp5 rbbp5 LOC102682223 LOC102682223 LOC102685425 LOC102685425 SMARCA2 SMARCA2 W5N0P4_LEPOC W5N0P4_LEPOC PPP2R5C PPP2R5C H3-3B H3-3B sox10 sox10 W5N1Z0_LEPOC W5N1Z0_LEPOC SOX13 SOX13 psmc5 psmc5 psmc6 psmc6 csnk1a1 csnk1a1 psme3 psme3 tnks tnks tcf7l2 tcf7l2 lef1 lef1 psma5 psma5 sox9 sox9 dkk2 dkk2 psmd3 psmd3 psmd11 psmd11 usp8 usp8 leo1 leo1 pygo1 pygo1 psmd12 psmd12 axin2 axin2 psmb3 psmb3 W5N8D2_LEPOC W5N8D2_LEPOC tle3 tle3 LOC102684155-2 LOC102684155-2 W5NA15_LEPOC W5NA15_LEPOC lrtm1 lrtm1 W5NA30_LEPOC W5NA30_LEPOC LOC102697092 LOC102697092 W5NAR9_LEPOC W5NAR9_LEPOC sox15 sox15 dact3 dact3 psmd10 psmd10 ruvbl1 ruvbl1 W5NBB2_LEPOC W5NBB2_LEPOC amer1 amer1 akt2 akt2 W5NBR2_LEPOC W5NBR2_LEPOC psma4 psma4 tcf7l1 tcf7l1 W5ND91_LEPOC W5ND91_LEPOC ash2l ash2l W5NDT6_LEPOC W5NDT6_LEPOC sox5 sox5 W5NE85_LEPOC W5NE85_LEPOC sfrp1 sfrp1 psmb1 psmb1 LOC102695536 LOC102695536 rps27a rps27a cav1 cav1 dkk4 dkk4 psmc2 psmc2 xpo1 xpo1 USP34 USP34 wif1 wif1 LGR5 LGR5 psme4 psme4 ppp2r5a ppp2r5a lrp6 lrp6 W5NID8_LEPOC W5NID8_LEPOC rspo3 rspo3 ppp2r5d ppp2r5d sox7 sox7 sox2 sox2 sox14 sox14 W5NLL5_LEPOC W5NLL5_LEPOC sox3 sox3 LOC102699233 LOC102699233 sox21 sox21 sox1 sox1 LOC102686492 LOC102686492 LOC102694187 LOC102694187 sox11 sox11 frat2 frat2 sox4 sox4 sox12 sox12
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
LOC102683700Uncharacterized protein. (148 aa)
W5LW40_LEPOCHMG box domain-containing protein. (167 aa)
W5LWJ3_LEPOCFrizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (584 aa)
W5LXB1_LEPOCUncharacterized protein. (53 aa)
W5LXB6_LEPOCCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (157 aa)
W5LXB8_LEPOCAPC regulator of WNT signaling pathway 2. (2430 aa)
psmb2Proteasome subunit beta. (200 aa)
W5LXK8_LEPOCUncharacterized protein. (133 aa)
W5LXQ3_LEPOCBcl9 like. (1241 aa)
W5LXX5_LEPOCAxin 1. (837 aa)
W5LYH4_LEPOCProteasome activator subunit 1. (161 aa)
W5LZH3_LEPOCProtein phosphatase 2, regulatory subunit A, beta b. (600 aa)
ctnnb1Catenin (cadherin-associated protein), beta 1. (780 aa)
sox8SRY-box transcription factor 8a. (408 aa)
men1Multiple endocrine neoplasia I. (239 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (153 aa)
csnk2a1Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (392 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (408 aa)
lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1602 aa)
crebbpCREB binding protein b. (2500 aa)
W5M4V5_LEPOCDishevelled segment polarity protein 1a. (778 aa)
RNF43Ring finger protein 43. (617 aa)
sox6SRY-box transcription factor 6. (831 aa)
rspo2R-spondin 2. (243 aa)
kremen1Kringle containing transmembrane protein 1. (459 aa)
znrf3Zinc and ring finger 3. (889 aa)
psma1Proteasome subunit alpha type. (268 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (522 aa)
W5M709_LEPOCTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1056 aa)
LOC102684155Histone H3; Belongs to the histone H3 family. (138 aa)
csnk2a2Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily. (393 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
cul3Cullin 3a; Belongs to the cullin family. (767 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (326 aa)
zbtb44Zinc finger and BTB domain containing 44. (616 aa)
W5M9W8_LEPOCZgc:162396. (234 aa)
W5M9Z0_LEPOCSi:ch211-93g23.2. (280 aa)
LOC102697712BTB domain-containing protein. (568 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
psmb7Proteasome subunit beta. (284 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (215 aa)
wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
sox18SRY-box transcription factor 18. (414 aa)
rykReceptor like tyrosine kinase. (656 aa)
sox17SRY-box transcription factor 17. (391 aa)
W5MFN8_LEPOCR-spondin 1. (263 aa)
TNKS2Poly [ADP-ribose] polymerase. (1167 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (443 aa)
SLC39A13Solute carrier family 39 member 13. (290 aa)
dkk1Dickkopf WNT signaling pathway inhibitor 1b. (250 aa)
psma8Proteasome subunit alpha type. (251 aa)
W5MH26_LEPOCTLE family member 2, transcriptional corepressor a. (792 aa)
tle5Chico. (199 aa)
lgr4Leucine-rich repeat containing G protein-coupled receptor 4. (967 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
bcl9BCL9 transcription coactivator. (1579 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (420 aa)
W5MJH0_LEPOCPygopus homolog 2 (Drosophila). (387 aa)
W5MJK0_LEPOCHistone H2B; Belongs to the histone H2B family. (136 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (528 aa)
LOC102684075Casein kinase 2, alpha 1 polypeptide; Belongs to the protein kinase superfamily. (392 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (531 aa)
psmf1Proteasome inhibitor subunit 1. (305 aa)
rspo4R-spondin 4. (247 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
W5MM76_LEPOCUncharacterized protein. (307 aa)
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1603 aa)
W5MP85_LEPOCDishevelled segment polarity protein 3a. (720 aa)
sfrp2Secreted frizzled-related protein 2. (298 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
W5MQE4_LEPOCTransformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family. (3821 aa)
sfrp5Secreted frizzled-related protein 5. (317 aa)
W5MRH9_LEPOCProteasome 26S subunit, ATPase 1a; Belongs to the AAA ATPase family. (441 aa)
psma6Proteasome subunit alpha type. (246 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
W5MSG6_LEPOCHelicase ATP-binding domain-containing protein. (100 aa)
W5MSH6_LEPOCChromo domain-containing protein. (185 aa)
psma2Proteasome subunit alpha type. (234 aa)
dact1Dishevelled-binding antagonist of beta-catenin 1. (821 aa)
psma3Proteasome subunit alpha type. (255 aa)
pip5k1bPhosphatidylinositol-4-phosphate 5-kinase, type I, beta b. (538 aa)
W5MTD3_LEPOCFrizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (606 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (931 aa)
W5MUA3_LEPOCProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (621 aa)
TLE4Uncharacterized protein. (776 aa)
tle1Uncharacterized protein. (780 aa)
KLHL12Kelch like family member 12. (599 aa)
ppp2r5eSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (467 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
W5MVZ9_LEPOCTranscription factor 7. (508 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
apcAPC regulator of WNT signaling pathway. (2836 aa)
W5MX40_LEPOCFrizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (160 aa)
hecw1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b. (1603 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
hmgxb3HMG box domain containing 3. (1284 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
rbbp5Retinoblastoma binding protein 5. (551 aa)
LOC102682223PCI domain-containing protein. (380 aa)
LOC102685425Zgc:162396. (272 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1600 aa)
W5N0P4_LEPOCE1A binding protein p300 a. (2068 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (581 aa)
H3-3BHistone H3; Belongs to the histone H3 family. (136 aa)
sox10HMG box domain-containing protein. (134 aa)
W5N1Z0_LEPOCFrizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (560 aa)
SOX13SRY-box transcription factor 13. (408 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (404 aa)
csnk1a1Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (337 aa)
psme3Proteasome activator subunit 3. (258 aa)
tnksPoly [ADP-ribose] polymerase. (1299 aa)
tcf7l2Transcription factor 7 like 2. (602 aa)
lef1Lymphoid enhancer-binding factor 1. (397 aa)
psma5Proteasome subunit alpha type. (241 aa)
sox9SRY-box transcription factor 9a. (479 aa)
dkk2Dickkopf WNT signaling pathway inhibitor 2. (253 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (514 aa)
psmd11Proteasome 26S subunit, non-ATPase 11b. (426 aa)
usp8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1075 aa)
leo1Uncharacterized protein. (652 aa)
pygo1Pygopus family PHD finger 1. (431 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (462 aa)
axin2Axin 2 (conductin, axil). (846 aa)
psmb3Proteasome subunit beta. (224 aa)
W5N8D2_LEPOCProteasome subunit beta 6. (225 aa)
tle3TLE family member 3, transcriptional corepressor a. (762 aa)
LOC102684155-2Histone H3.3. (136 aa)
W5NA15_LEPOCProteasome endopeptidase complex; Belongs to the peptidase T1A family. (250 aa)
lrtm1Leucine rich repeats and transmembrane domains 1. (349 aa)
W5NA30_LEPOCProteasome 26S subunit, non-ATPase 8. (292 aa)
LOC102697092Uncharacterized protein. (303 aa)
W5NAR9_LEPOCDishevelled segment polarity protein 2. (708 aa)
sox15SRY-box transcription factor 19a. (304 aa)
dact3Dishevelled-binding antagonist of beta-catenin 3a. (658 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (228 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (270 aa)
W5NBB2_LEPOCX-linked inhibitor of apoptosis. (267 aa)
amer1APC membrane recruitment protein 1. (918 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
W5NBR2_LEPOCLow density lipoprotein receptor-related protein 4. (1887 aa)
psma4Proteasome subunit alpha type. (261 aa)
tcf7l1Transcription factor 7 like 1b. (577 aa)
W5ND91_LEPOCUncharacterized protein. (96 aa)
ash2lAsh2 like, histone lysine methyltransferase complex subunit. (624 aa)
W5NDT6_LEPOCHistone H2A; Belongs to the histone H2A family. (129 aa)
sox5SRY-box transcription factor 5. (774 aa)
W5NE85_LEPOCNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (469 aa)
sfrp1Secreted frizzled-related protein 1a. (316 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC102695536Sizzled. (294 aa)
rps27aRibosomal protein S27a. (162 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
dkk4Uncharacterized protein. (267 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
xpo1Exportin 1 (CRM1 homolog, yeast) a. (1076 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3561 aa)
wif1Wnt inhibitory factor 1. (378 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (905 aa)
psme4Proteasome activator subunit 4b. (1848 aa)
ppp2r5aSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (479 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
W5NID8_LEPOCRing finger protein 146. (346 aa)
rspo3R-spondin 3. (327 aa)
ppp2r5dSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (613 aa)
sox7SRY-box transcription factor 7. (373 aa)
sox2SRY-box transcription factor 2. (315 aa)
sox14SRY-box transcription factor 14. (238 aa)
W5NLL5_LEPOCHistone H2B; Belongs to the histone H2B family. (115 aa)
sox3SRY-box transcription factor 3. (305 aa)
LOC102699233Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
sox21SRY-box transcription factor 21b. (247 aa)
sox1SRY-box transcription factor 1b. (343 aa)
LOC102686492Histone H2A; Belongs to the histone H2A family. (141 aa)
LOC102694187Histone H2A; Belongs to the histone H2A family. (142 aa)
sox11Transcription factor SOX. (361 aa)
frat2Glycogen synthase kinase binding protein. (173 aa)
sox4Transcription factor SOX. (378 aa)
sox12Transcription factor SOX. (365 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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