STRINGSTRING
W5NIY2_LEPOC W5NIY2_LEPOC EPHA7 EPHA7 fyn fyn actr3b actr3b W5N4E0_LEPOC W5N4E0_LEPOC LOC102698253 LOC102698253 itsn1 itsn1 LOC102685777 LOC102685777 LOC102684806 LOC102684806 ACTG1 ACTG1 psen1 psen1 efnb3 efnb3 W5N891_LEPOC W5N891_LEPOC PAK3 PAK3 W5NAX1_LEPOC W5NAX1_LEPOC W5NB73_LEPOC W5NB73_LEPOC efnb1 efnb1 LOC102694001 LOC102694001 ap2s1 ap2s1 W5NCT9_LEPOC W5NCT9_LEPOC LOC102683678 LOC102683678 wasl wasl W5NG78_LEPOC W5NG78_LEPOC actr2 actr2 LOC102689245 LOC102689245 W5MKZ6_LEPOC W5MKZ6_LEPOC W5MMP0_LEPOC W5MMP0_LEPOC epha2 epha2 W5MNT4_LEPOC W5MNT4_LEPOC ap2m1 ap2m1 ephb3 ephb3 arhgef7 arhgef7 tiam1 tiam1 ngef ngef EFNA5 EFNA5 arpc2 arpc2 W5MSK9_LEPOC W5MSK9_LEPOC W5MSV8_LEPOC W5MSV8_LEPOC cfl2 cfl2 epha6 epha6 epha3 epha3 yes1 yes1 fmn2 fmn2 efnb2 efnb2 clta clta W5N0V1_LEPOC W5N0V1_LEPOC W5N1X4_LEPOC W5N1X4_LEPOC W5N265_LEPOC W5N265_LEPOC APH1A APH1A pak1 pak1 epha10 epha10 LOC102689748 LOC102689748 LOC102684556 LOC102684556 pak2 pak2 SDCBP SDCBP arpc5l arpc5l dnm1 dnm1 actb actb LOC102695161 LOC102695161 LOC102694828 LOC102694828 vav2 vav2 epha4 epha4 cltc cltc sdc2 sdc2 ephb2 ephb2 actr3 actr3 EPHA5 EPHA5 W5M3T2_LEPOC W5M3T2_LEPOC W5M302_LEPOC W5M302_LEPOC LOC102697324 LOC102697324 W5M1U6_LEPOC W5M1U6_LEPOC rasa1 rasa1 NCSTN NCSTN ap2b1 ap2b1 LOC102698575 LOC102698575 arpc5 arpc5 cdc42 cdc42 EPHA8 EPHA8 hras hras grin1 grin1 VAV1 VAV1 arpc3 arpc3 mmp2 mmp2 W5MIU6_LEPOC W5MIU6_LEPOC LOC102688062 LOC102688062
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5NIY2_LEPOCRho-associated, coiled-coil containing protein kinase 2b; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1449 aa)
EPHA7EPH receptor A7. (995 aa)
fynTyrosine-protein kinase. (538 aa)
actr3bActin related protein 3B; Belongs to the actin family. (426 aa)
W5N4E0_LEPOCFormin 1. (1292 aa)
LOC102698253Cell division cycle 42, like. (191 aa)
itsn1Intersectin 1 (SH3 domain protein). (1730 aa)
LOC102685777Ephrin-A3b; Belongs to the ephrin family. (166 aa)
LOC102684806Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (359 aa)
ACTG1Uncharacterized protein. (434 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (522 aa)
efnb3Ephrin-B3a; Belongs to the ephrin family. (354 aa)
W5N891_LEPOCEph receptor B4b. (706 aa)
PAK3Non-specific serine/threonine protein kinase. (580 aa)
W5NAX1_LEPOCWASP actin nucleation promoting factor b. (507 aa)
W5NB73_LEPOCActin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (184 aa)
efnb1Ephrin-B1; Belongs to the ephrin family. (334 aa)
LOC102694001APH1B gamma secretase subunit. (175 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
W5NCT9_LEPOCUncharacterized protein. (1174 aa)
LOC102683678Cofilin 1 (non-muscle), like; Belongs to the actin-binding proteins ADF family. (164 aa)
waslWASP like actin nucleation promoting factor b. (513 aa)
W5NG78_LEPOCPresenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
LOC102689245Zgc:114200. (256 aa)
W5MKZ6_LEPOCFibronectin type III domain containing 3Ba. (1120 aa)
W5MMP0_LEPOCVav 3 guanine nucleotide exchange factor b. (852 aa)
epha2Eph receptor A2 b. (980 aa)
W5MNT4_LEPOCReceptor protein-tyrosine kinase. (870 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (440 aa)
ephb3Uncharacterized protein. (996 aa)
arhgef7Rho guanine nucleotide exchange factor (GEF) 7a. (862 aa)
tiam1T cell lymphoma invasion and metastasis 1a. (1592 aa)
ngefNeuronal guanine nucleotide exchange factor. (561 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (229 aa)
arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (303 aa)
W5MSK9_LEPOCFibronectin type III domain containing 3A. (1193 aa)
W5MSV8_LEPOCUncharacterized protein. (377 aa)
cfl2Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (201 aa)
epha6Eph receptor A6. (1000 aa)
epha3Eph receptor A3. (983 aa)
yes1Tyrosine-protein kinase. (545 aa)
fmn2Formin 2a. (1412 aa)
efnb2Ephrin-B2a; Belongs to the ephrin family. (337 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (246 aa)
W5N0V1_LEPOCSi:dkey-280e21.3. (440 aa)
W5N1X4_LEPOCClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
W5N265_LEPOCGlutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (988 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (246 aa)
pak1Non-specific serine/threonine protein kinase. (551 aa)
epha10Uncharacterized protein. (1018 aa)
LOC102689748Uncharacterized protein. (300 aa)
LOC102684556EPH receptor B1. (984 aa)
pak2Non-specific serine/threonine protein kinase. (529 aa)
SDCBPSyndecan binding protein. (304 aa)
arpc5lActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (101 aa)
dnm1Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (858 aa)
actbActin, beta 1. (377 aa)
LOC102695161Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
LOC102694828Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (369 aa)
vav2Vav 2 guanine nucleotide exchange factor. (879 aa)
epha4Eph receptor A4, like. (984 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1688 aa)
sdc2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (218 aa)
ephb2Eph receptor B2b. (993 aa)
actr3Actin related protein 3; Belongs to the actin family. (418 aa)
EPHA5EPH receptor A5. (990 aa)
W5M3T2_LEPOCFibronectin type-III domain-containing protein. (314 aa)
W5M302_LEPOCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1363 aa)
LOC102697324Tyrosine-protein kinase. (542 aa)
W5M1U6_LEPOCRho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1b. (1035 aa)
NCSTNNicastrin. (442 aa)
ap2b1Adaptor related protein complex 2 subunit beta 1. (950 aa)
LOC102698575Ephrin-A2a; Belongs to the ephrin family. (197 aa)
arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa)
cdc42Cell division cycle 42. (195 aa)
EPHA8EPH receptor A8. (996 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
grin1Glutamate receptor, ionotropic, N-methyl D-aspartate 1b. (986 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
arpc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
mmp2Matrix metallopeptidase 2. (658 aa)
W5MIU6_LEPOCMatrix metallopeptidase 9. (658 aa)
LOC102688062Eph receptor A4b. (976 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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