STRINGSTRING
rfc4 rfc4 rpa3 rpa3 W5MSA1_LEPOC W5MSA1_LEPOC LOC102685849 LOC102685849 rfc3 rfc3 rpa1 rpa1 meiob meiob W5M9S6_LEPOC W5M9S6_LEPOC pole pole pole4 pole4 rfc5 rfc5 rpa2 rpa2 pole3 pole3 pold3 pold3 W5M103_LEPOC W5M103_LEPOC rfc2 rfc2 W5LXJ3_LEPOC W5LXJ3_LEPOC pole2 pole2 rfc1 rfc1 W5N8N6_LEPOC W5N8N6_LEPOC apex2 apex2 pold2 pold2 apex1 apex1 polb polb pcna pcna
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfc4Replication factor C (activator 1) 4. (359 aa)
rpa3Replication protein A3. (121 aa)
W5MSA1_LEPOCRegulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (613 aa)
LOC102685849Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
W5M9S6_LEPOCXPGI domain-containing protein. (345 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2298 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (135 aa)
rfc5Replication factor C (activator 1) 5. (367 aa)
rpa2Replication protein A2. (277 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
W5M103_LEPOCDNA ligase. (1030 aa)
rfc2Replication factor C (activator 1) 2. (358 aa)
W5LXJ3_LEPOCDNA_pol_B domain-containing protein. (97 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
rfc1Replication factor C subunit 1. (1204 aa)
W5N8N6_LEPOCATPase family AAA domain containing 5a. (1812 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (569 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (317 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (14%) [HD]