STRINGSTRING
W5M1E5_LEPOC W5M1E5_LEPOC polr2j polr2j W5M103_LEPOC W5M103_LEPOC rfc2 rfc2 rfc4 rfc4 W5LV61_LEPOC W5LV61_LEPOC W5LVC1_LEPOC W5LVC1_LEPOC LOC107076457 LOC107076457 W5LWZ8_LEPOC W5LWZ8_LEPOC W5LXJ3_LEPOC W5LXJ3_LEPOC W5MSA1_LEPOC W5MSA1_LEPOC W5N8N6_LEPOC W5N8N6_LEPOC rfc1 rfc1 aqr aqr polr2k polr2k polr2f polr2f W5N0P4_LEPOC W5N0P4_LEPOC polr2b polr2b pole2 pole2 rpa3 rpa3 uvssa uvssa LOC102695873 LOC102695873 usp40 usp40 mnat1 mnat1 cul4a cul4a TCEANC TCEANC pcna pcna rps27a rps27a cul4b cul4b pold2 pold2 W5ND91_LEPOC W5ND91_LEPOC polr2i polr2i W5NAQ1_LEPOC W5NAQ1_LEPOC phf3 phf3 gtf2h5 gtf2h5 polr2d polr2d nrde2 nrde2 polr2h polr2h LOC102685849 LOC102685849 rfc3 rfc3 W5MNA9_LEPOC W5MNA9_LEPOC W5MM08_LEPOC W5MM08_LEPOC W5MJA1_LEPOC W5MJA1_LEPOC LOC107075828 LOC107075828 rpa1 rpa1 W5MGN2_LEPOC W5MGN2_LEPOC cdk7 cdk7 gtf2h3 gtf2h3 tcea1 tcea1 xrcc1 xrcc1 W5MDZ8_LEPOC W5MDZ8_LEPOC W5MDK3_LEPOC W5MDK3_LEPOC meiob meiob polr2a polr2a isy1 isy1 ZNF830 ZNF830 polr2e polr2e LOC102695765 LOC102695765 LOC102689318 LOC102689318 pole pole LOC102697492 LOC102697492 pole4 pole4 rfc5 rfc5 W5M601_LEPOC W5M601_LEPOC polr2c polr2c rpa2 rpa2 pole3 pole3 pold3 pold3 W5M2Q0_LEPOC W5M2Q0_LEPOC uba52 uba52 lig3 lig3 ccnh ccnh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5M1E5_LEPOCPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (134 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (132 aa)
W5M103_LEPOCDNA ligase. (1030 aa)
rfc2Replication factor C (activator 1) 2. (358 aa)
rfc4Replication factor C (activator 1) 4. (359 aa)
W5LV61_LEPOCDamage-specific DNA binding protein 1. (1044 aa)
W5LVC1_LEPOCUncharacterized protein. (168 aa)
LOC107076457Uncharacterized protein. (171 aa)
W5LWZ8_LEPOCDEAD_2 domain-containing protein. (153 aa)
W5LXJ3_LEPOCDNA_pol_B domain-containing protein. (97 aa)
W5MSA1_LEPOCRegulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (613 aa)
W5N8N6_LEPOCATPase family AAA domain containing 5a. (1812 aa)
rfc1Replication factor C subunit 1. (1204 aa)
aqrAquarius intron-binding spliceosomal factor. (1463 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (130 aa)
W5N0P4_LEPOCE1A binding protein p300 a. (2068 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1176 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
rpa3Replication protein A3. (121 aa)
uvssaUV-stimulated scaffold protein A. (758 aa)
LOC102695873Excision repair cross-complementation group 3. (813 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1241 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (310 aa)
cul4aCullin 4A; Belongs to the cullin family. (755 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (374 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
rps27aRibosomal protein S27a. (162 aa)
cul4bCullin 4B; Belongs to the cullin family. (864 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
W5ND91_LEPOCUncharacterized protein. (96 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
W5NAQ1_LEPOCExcision repair cross-complementation group 2. (760 aa)
phf3PHD finger protein 3. (1962 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1159 aa)
polr2hInfo polymerase (RNA) II (DNA directed) polypeptide H. (112 aa)
LOC102685849Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
W5MNA9_LEPOCPre-mRNA processing factor 19. (465 aa)
W5MM08_LEPOCExcision repair cross-complementation group 8. (393 aa)
W5MJA1_LEPOCXPA binding protein 2. (845 aa)
LOC107075828BSD domain-containing protein. (170 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
W5MGN2_LEPOCUbiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1129 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (348 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (301 aa)
tcea1Transcription elongation factor A (SII), 1. (313 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (648 aa)
W5MDZ8_LEPOCPolymerase (DNA directed) kappa. (839 aa)
W5MDK3_LEPOCTranscription elongation factor A (SII), 2. (360 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1959 aa)
isy1ISY1 splicing factor homolog. (319 aa)
ZNF830Zinc finger protein 830. (352 aa)
polr2eRNA polymerase II subunit E. (162 aa)
LOC102695765General transcription factor IIH subunit. (392 aa)
LOC102689318Excision repair cross-complementation group 6. (1446 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2298 aa)
LOC102697492Transcription elongation factor A (SII), 3. (491 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (135 aa)
rfc5Replication factor C (activator 1) 5. (367 aa)
W5M601_LEPOCTranscription elongation factor A (SII) N-terminal and central domain containing 2. (343 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
rpa2Replication protein A2. (277 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
W5M2Q0_LEPOCUncharacterized protein. (250 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (153 aa)
lig3DNA ligase. (1001 aa)
ccnhCyclin H; Belongs to the cyclin family. (322 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.