17 items (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prim2	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (512 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
	W5N8N6_LEPOC	ATPase family AAA domain containing 5a. (1812 aa)
	rfc1	Replication factor C subunit 1. (1204 aa)
	W5MSA1_LEPOC	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (613 aa)
	LOC102685849	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	prim1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa)
	rfc5	Replication factor C (activator 1) 5. (367 aa)
	W5M4I8_LEPOC	Uncharacterized protein. (168 aa)
	W5M4G9_LEPOC	DNA_pol_E_B domain-containing protein. (66 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
	pola1	DNA polymerase. (1486 aa)
	rfc2	Replication factor C (activator 1) 2. (358 aa)
	rfc4	Replication factor C (activator 1) 4. (359 aa)
	W5LXJ3_LEPOC	DNA_pol_B domain-containing protein. (97 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W5LXJ3_LEPOC	W5M4G9_LEPOC	ENSLOCP00000000850	ENSLOCP00000003277	DNA_pol_B domain-containing protein.	DNA_pol_E_B domain-containing protein.	0.981
W5LXJ3_LEPOC	W5M4I8_LEPOC	ENSLOCP00000000850	ENSLOCP00000003296	DNA_pol_B domain-containing protein.	Uncharacterized protein.	0.981
W5LXJ3_LEPOC	W5N8N6_LEPOC	ENSLOCP00000000850	ENSLOCP00000016995	DNA_pol_B domain-containing protein.	ATPase family AAA domain containing 5a.	0.857
W5LXJ3_LEPOC	pcna	ENSLOCP00000000850	ENSLOCP00000019251	DNA_pol_B domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.998
W5LXJ3_LEPOC	pola1	ENSLOCP00000000850	ENSLOCP00000002197	DNA_pol_B domain-containing protein.	DNA polymerase.	0.985
W5LXJ3_LEPOC	pold2	ENSLOCP00000000850	ENSLOCP00000018670	DNA_pol_B domain-containing protein.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.999
W5LXJ3_LEPOC	pold3	ENSLOCP00000000850	ENSLOCP00000002686	DNA_pol_B domain-containing protein.	Polymerase (DNA-directed), delta 3, accessory subunit.	0.997
W5LXJ3_LEPOC	prim1	ENSLOCP00000000850	ENSLOCP00000008896	DNA_pol_B domain-containing protein.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.992
W5LXJ3_LEPOC	prim2	ENSLOCP00000000850	ENSLOCP00000021029	DNA_pol_B domain-containing protein.	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	0.992
W5LXJ3_LEPOC	rfc1	ENSLOCP00000000850	ENSLOCP00000016043	DNA_pol_B domain-containing protein.	Replication factor C subunit 1.	0.865
W5LXJ3_LEPOC	rfc2	ENSLOCP00000000850	ENSLOCP00000000995	DNA_pol_B domain-containing protein.	Replication factor C (activator 1) 2.	0.870
W5LXJ3_LEPOC	rfc3	ENSLOCP00000000850	ENSLOCP00000010111	DNA_pol_B domain-containing protein.	Replication factor C (activator 1) 3.	0.897
W5LXJ3_LEPOC	rfc4	ENSLOCP00000000850	ENSLOCP00000000979	DNA_pol_B domain-containing protein.	Replication factor C (activator 1) 4.	0.936
W5LXJ3_LEPOC	rfc5	ENSLOCP00000000850	ENSLOCP00000003944	DNA_pol_B domain-containing protein.	Replication factor C (activator 1) 5.	0.843
W5M4G9_LEPOC	W5LXJ3_LEPOC	ENSLOCP00000003277	ENSLOCP00000000850	DNA_pol_E_B domain-containing protein.	DNA_pol_B domain-containing protein.	0.981
W5M4G9_LEPOC	W5M4I8_LEPOC	ENSLOCP00000003277	ENSLOCP00000003296	DNA_pol_E_B domain-containing protein.	Uncharacterized protein.	0.540
W5M4G9_LEPOC	W5N8N6_LEPOC	ENSLOCP00000003277	ENSLOCP00000016995	DNA_pol_E_B domain-containing protein.	ATPase family AAA domain containing 5a.	0.831
W5M4G9_LEPOC	pcna	ENSLOCP00000003277	ENSLOCP00000019251	DNA_pol_E_B domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.912
W5M4G9_LEPOC	pola1	ENSLOCP00000003277	ENSLOCP00000002197	DNA_pol_E_B domain-containing protein.	DNA polymerase.	0.998
W5M4G9_LEPOC	pold2	ENSLOCP00000003277	ENSLOCP00000018670	DNA_pol_E_B domain-containing protein.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.935