18 items (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5MFN8_LEPOC	R-spondin 1. (263 aa)
	rspo2	R-spondin 2. (243 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (675 aa)
	insr	Tyrosine-protein kinase receptor. (1365 aa)
	W5M7P2_LEPOC	Erb-b2 receptor tyrosine kinase 3b. (1370 aa)
	rspo3	R-spondin 3. (327 aa)
	W5NGK2_LEPOC	Cysteine-rich with EGF-like domains 2. (367 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (755 aa)
	LOC107076937	Uncharacterized protein. (221 aa)
	LOC107076936	Uncharacterized protein. (104 aa)
	igf1r	Tyrosine-protein kinase receptor. (1180 aa)
	pcsk6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (916 aa)
	erbb2	Receptor protein-tyrosine kinase. (1255 aa)
	W5N0P5_LEPOC	Receptor protein-tyrosine kinase. (1210 aa)
	pcsk5	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family. (1855 aa)
	rspo4	R-spondin 4. (247 aa)
	W5MKP6_LEPOC	Fraser extracellular matrix complex subunit 1. (4004 aa)
	W5MAN3_LEPOC	Receptor protein-tyrosine kinase. (1307 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107076936	LOC107076937	ENSLOCP00000018220	ENSLOCP00000018222	Uncharacterized protein.	Uncharacterized protein.	0.439
LOC107076937	LOC107076936	ENSLOCP00000018222	ENSLOCP00000018220	Uncharacterized protein.	Uncharacterized protein.	0.439
LOC107076937	furin	ENSLOCP00000018222	ENSLOCP00000018567	Uncharacterized protein.	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.	0.542
LOC107076937	pcsk6	ENSLOCP00000018222	ENSLOCP00000017367	Uncharacterized protein.	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family.	0.528
W5M7P2_LEPOC	erbb2	ENSLOCP00000004400	ENSLOCP00000015640	Erb-b2 receptor tyrosine kinase 3b.	Receptor protein-tyrosine kinase.	0.834
W5M7P2_LEPOC	igf1r	ENSLOCP00000004400	ENSLOCP00000017791	Erb-b2 receptor tyrosine kinase 3b.	Tyrosine-protein kinase receptor.	0.654
W5M7P2_LEPOC	insr	ENSLOCP00000004400	ENSLOCP00000005036	Erb-b2 receptor tyrosine kinase 3b.	Tyrosine-protein kinase receptor.	0.654
W5MAN3_LEPOC	erbb2	ENSLOCP00000005442	ENSLOCP00000015640	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.826
W5MAN3_LEPOC	igf1r	ENSLOCP00000005442	ENSLOCP00000017791	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654
W5MAN3_LEPOC	insr	ENSLOCP00000005442	ENSLOCP00000005036	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654
W5MFN8_LEPOC	rspo2	ENSLOCP00000007197	ENSLOCP00000003686	R-spondin 1.	R-spondin 2.	0.861
W5MFN8_LEPOC	rspo3	ENSLOCP00000007197	ENSLOCP00000020398	R-spondin 1.	R-spondin 3.	0.858
W5MFN8_LEPOC	rspo4	ENSLOCP00000007197	ENSLOCP00000009033	R-spondin 1.	R-spondin 4.	0.713
W5N0P5_LEPOC	erbb2	ENSLOCP00000014204	ENSLOCP00000015640	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.866
W5N0P5_LEPOC	igf1r	ENSLOCP00000014204	ENSLOCP00000017791	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654
W5N0P5_LEPOC	insr	ENSLOCP00000014204	ENSLOCP00000005036	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654
erbb2	W5M7P2_LEPOC	ENSLOCP00000015640	ENSLOCP00000004400	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3b.	0.834
erbb2	W5MAN3_LEPOC	ENSLOCP00000015640	ENSLOCP00000005442	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.826
erbb2	W5N0P5_LEPOC	ENSLOCP00000015640	ENSLOCP00000014204	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.866
erbb2	igf1r	ENSLOCP00000015640	ENSLOCP00000017791	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654