(58 nodes) Basal transcription factors network (Lepisosteus oculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	styx	Serine/threonine/tyrosine interacting protein. (224 aa)
	W5N1N1_LEPOC	Programmed cell death 11. (1798 aa)
	W5N1K4_LEPOC	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (772 aa)
	W5MZQ6_LEPOC	Small G protein signaling modulator 3. (622 aa)
	W5MZD6_LEPOC	WD repeat domain 55. (729 aa)
	W5MYI6_LEPOC	Uncharacterized protein. (747 aa)
	LOC102695873	Excision repair cross-complementation group 3. (813 aa)
	W5MXZ8_LEPOC	N-6 adenine-specific DNA methyltransferase 1. (214 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (310 aa)
	taf4	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1055 aa)
	LOC102695765	General transcription factor IIH subunit. (392 aa)
	W5MBK9_LEPOC	THAP domain containing 12b. (758 aa)
	gtf2b	General transcription factor IIB. (316 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (274 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (301 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (348 aa)
	nelfcd	Negative elongation factor complex member C/D. (539 aa)
	gtf2e1	General transcription factor IIE, polypeptide 1, alpha. (442 aa)
	TAF4B	TATA-box binding protein associated factor 4b. (847 aa)
	W5MGZ7_LEPOC	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (455 aa)
	ebna1bp2	EBNA1 binding protein 2. (316 aa)
	ing5	Inhibitor of growth protein. (241 aa)
	d2hgdh	D-2-hydroxyglutarate dehydrogenase. (533 aa)
	LOC107075828	BSD domain-containing protein. (170 aa)
	W5MJF7_LEPOC	Inhibitor of growth protein. (253 aa)
	gtf2a1	General transcription factor IIA, 1. (378 aa)
	STON2	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (873 aa)
	ing1	Inhibitor of growth protein. (258 aa)
	taf2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1217 aa)
	taf11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (206 aa)
	LOC102687787	General transcription factor IIA, 1-like. (1146 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	tbpl1	TBP-like 1. (186 aa)
	ing3	Inhibitor of growth protein. (418 aa)
	W5NF96_LEPOC	PHD-type domain-containing protein. (223 aa)
	tbp	TATA box binding protein. (313 aa)
	LOC107076314	Uncharacterized protein. (123 aa)
	W5LWZ8_LEPOC	DEAD_2 domain-containing protein. (153 aa)
	CLSPN	Claspin. (1303 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (322 aa)
	LOC102692312	Si:dkey-219c3.2. (1106 aa)
	W5M2A3_LEPOC	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (197 aa)
	taf5l	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (493 aa)
	W5M2F8_LEPOC	GTF2I repeat domain containing 1. (977 aa)
	W5M3F8_LEPOC	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
	taf13	TATA-box binding protein associated factor 13. (124 aa)
	taf12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (216 aa)
	taf7l	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (371 aa)
	taf1	Transcription initiation factor TFIID subunit. (1966 aa)
	W5NC59_LEPOC	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	W5NC57_LEPOC	BCL2 interacting protein 2. (440 aa)
	cdk20	Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (344 aa)
	W5NAQ1_LEPOC	Excision repair cross-complementation group 2. (760 aa)
	fbxw12	Si:ch73-142c19.1. (482 aa)
	taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (668 aa)
	taf9b	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (259 aa)
	gtf2e2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (293 aa)
	taf8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (312 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLSPN	W5LWZ8_LEPOC	ENSLOCP00000000701	ENSLOCP00000000655	Claspin.	DEAD_2 domain-containing protein.	0.558
CLSPN	W5NAQ1_LEPOC	ENSLOCP00000000701	ENSLOCP00000017710	Claspin.	Excision repair cross-complementation group 2.	0.558
LOC102687787	LOC102692312	ENSLOCP00000020092	ENSLOCP00000002308	General transcription factor IIA, 1-like.	Si:dkey-219c3.2.	0.856
LOC102687787	LOC102695765	ENSLOCP00000020092	ENSLOCP00000005192	General transcription factor IIA, 1-like.	General transcription factor IIH subunit.	0.974
LOC102687787	LOC102695873	ENSLOCP00000020092	ENSLOCP00000013382	General transcription factor IIA, 1-like.	Excision repair cross-complementation group 3.	0.967
LOC102687787	LOC107075828	ENSLOCP00000020092	ENSLOCP00000008240	General transcription factor IIA, 1-like.	BSD domain-containing protein.	0.962
LOC102687787	LOC107076314	ENSLOCP00000020092	ENSLOCP00000000503	General transcription factor IIA, 1-like.	Uncharacterized protein.	0.791
LOC102687787	STON2	ENSLOCP00000020092	ENSLOCP00000010906	General transcription factor IIA, 1-like.	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.	0.520
LOC102687787	TAF4B	ENSLOCP00000020092	ENSLOCP00000007652	General transcription factor IIA, 1-like.	TATA-box binding protein associated factor 4b.	0.856
LOC102687787	W5LWZ8_LEPOC	ENSLOCP00000020092	ENSLOCP00000000655	General transcription factor IIA, 1-like.	DEAD_2 domain-containing protein.	0.913
LOC102687787	W5M2A3_LEPOC	ENSLOCP00000020092	ENSLOCP00000002511	General transcription factor IIA, 1-like.	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor.	0.819
LOC102687787	W5M3F8_LEPOC	ENSLOCP00000020092	ENSLOCP00000002916	General transcription factor IIA, 1-like.	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.866
LOC102687787	W5MGZ7_LEPOC	ENSLOCP00000020092	ENSLOCP00000007656	General transcription factor IIA, 1-like.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.973
LOC102687787	W5MYI6_LEPOC	ENSLOCP00000020092	ENSLOCP00000013445	General transcription factor IIA, 1-like.	Uncharacterized protein.	0.714
LOC102687787	W5N1K4_LEPOC	ENSLOCP00000020092	ENSLOCP00000014513	General transcription factor IIA, 1-like.	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.714
LOC102687787	W5NAQ1_LEPOC	ENSLOCP00000020092	ENSLOCP00000017710	General transcription factor IIA, 1-like.	Excision repair cross-complementation group 2.	0.913
LOC102687787	W5NC59_LEPOC	ENSLOCP00000020092	ENSLOCP00000018218	General transcription factor IIA, 1-like.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.996
LOC102687787	W5NF96_LEPOC	ENSLOCP00000020092	ENSLOCP00000019305	General transcription factor IIA, 1-like.	PHD-type domain-containing protein.	0.828
LOC102687787	ccnh	ENSLOCP00000020092	ENSLOCP00000002213	General transcription factor IIA, 1-like.	Cyclin H; Belongs to the cyclin family.	0.872
LOC102687787	cdk20	ENSLOCP00000020092	ENSLOCP00000018168	General transcription factor IIA, 1-like.	Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily.	0.715