STRINGSTRING
W5MHC5_LEPOC W5MHC5_LEPOC lig3 lig3 pole2 pole2 mettl4 mettl4 W5MXX0_LEPOC W5MXX0_LEPOC parp3 parp3 W5MUQ0_LEPOC W5MUQ0_LEPOC W5NNG6_LEPOC W5NNG6_LEPOC GEN1 GEN1 parp1 parp1 pcna pcna polb polb apex1 apex1 pold2 pold2 tdg tdg W5NCJ0_LEPOC W5NCJ0_LEPOC W5NBX2_LEPOC W5NBX2_LEPOC W5NB54_LEPOC W5NB54_LEPOC W5NB45_LEPOC W5NB45_LEPOC apex2 apex2 neil3 neil3 hmgb2 hmgb2 MBD4 MBD4 W5MQ35_LEPOC W5MQ35_LEPOC chrac1 chrac1 hmgb1 hmgb1 W5LVZ4_LEPOC W5LVZ4_LEPOC adat2 adat2 W5LXJ3_LEPOC W5LXJ3_LEPOC GTF3C1 GTF3C1 W5M103_LEPOC W5M103_LEPOC r3hdml r3hdml W5MFH8_LEPOC W5MFH8_LEPOC xrcc1 xrcc1 ung ung W5M9S6_LEPOC W5M9S6_LEPOC crispld2 crispld2 W5MFZ1_LEPOC W5MFZ1_LEPOC mpg mpg MGMT MGMT cachd1 cachd1 poll poll W5N155_LEPOC W5N155_LEPOC pole pole crispld1 crispld1 MBD2 MBD2 pole4 pole4 W5M5R0_LEPOC W5M5R0_LEPOC NTHL1 NTHL1 MUTYH MUTYH pole3 pole3 prkrip1 prkrip1 pold3 pold3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5MHC5_LEPOCSingle-strand-selective monofunctional uracil-DNA glycosylase 1. (268 aa)
lig3DNA ligase. (1001 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
mettl4Methyltransferase like 4; Belongs to the MT-A70-like family. (482 aa)
W5MXX0_LEPOCPoly [ADP-ribose] polymerase. (1701 aa)
parp3Poly [ADP-ribose] polymerase. (516 aa)
W5MUQ0_LEPOCUncharacterized protein. (204 aa)
W5NNG6_LEPOCUncharacterized protein. (333 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (461 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1009 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (317 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
tdgThymine DNA glycosylase, tandem duplicate 2. (247 aa)
W5NCJ0_LEPOCNei-like DNA glycosylase 1. (416 aa)
W5NBX2_LEPOCMethyl CpG binding protein 2. (499 aa)
W5NB54_LEPOC8-oxoguanine DNA glycosylase. (354 aa)
W5NB45_LEPOCHigh mobility group box 3a. (214 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (569 aa)
neil3Nei-like DNA glycosylase 3. (579 aa)
hmgb2High mobility group box 2a. (219 aa)
MBD4MBD domain-containing protein. (497 aa)
W5MQ35_LEPOCNucleolar and coiled-body phosphoprotein 1. (980 aa)
chrac1Chromatin accessibility complex subunit 1. (116 aa)
hmgb1High mobility group box 1a. (212 aa)
W5LVZ4_LEPOCPoly [ADP-ribose] polymerase. (480 aa)
adat2Adenosine deaminase tRNA specific 2. (190 aa)
W5LXJ3_LEPOCDNA_pol_B domain-containing protein. (97 aa)
GTF3C1General transcription factor IIIC subunit 1. (2119 aa)
W5M103_LEPOCDNA ligase. (1030 aa)
r3hdmlR3H domain containing-like. (267 aa)
W5MFH8_LEPOCVon Willebrand factor A domain containing 5B2. (1207 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (648 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (302 aa)
W5M9S6_LEPOCXPGI domain-containing protein. (345 aa)
crispld2Cysteine-rich secretory protein LCCL domain containing 2. (508 aa)
W5MFZ1_LEPOCMethyl-CpG binding domain protein 3a. (307 aa)
mpgN-methylpurine DNA glycosylase. (279 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (242 aa)
cachd1Cache domain containing 1. (1292 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (579 aa)
W5N155_LEPOCSi:ch211-141o9.10. (170 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2298 aa)
crispld1Cysteine-rich secretory protein LCCL domain containing 1b. (510 aa)
MBD2Methyl-CpG binding domain protein 2. (266 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (135 aa)
W5M5R0_LEPOCPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (168 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (340 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (510 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
prkrip1PRKR interacting protein 1. (188 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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