STRINGSTRING
W5NJQ6_LEPOC W5NJQ6_LEPOC gtf2h5 gtf2h5 W5NF63_LEPOC W5NF63_LEPOC pcna pcna cul4b cul4b pold2 pold2 znf609 znf609 cdk20 cdk20 wdr76 wdr76 W5NAQ1_LEPOC W5NAQ1_LEPOC fbxw12 fbxw12 W5N8N6_LEPOC W5N8N6_LEPOC W5N634_LEPOC W5N634_LEPOC rfc1 rfc1 stn1 stn1 pole2 pole2 rpa3 rpa3 LOC102695873 LOC102695873 LOC102688897 LOC102688897 mnat1 mnat1 W5MVA4_LEPOC W5MVA4_LEPOC RAD23B RAD23B cul4a cul4a xpa xpa ZNF608 ZNF608 bivm bivm rfc3 rfc3 rad23a rad23a chrac1 chrac1 W5MM08_LEPOC W5MM08_LEPOC ercc4 ercc4 LOC107075828 LOC107075828 rpa1 rpa1 ercc1 ercc1 cdk7 cdk7 gtf2h3 gtf2h3 W5LV61_LEPOC W5LV61_LEPOC ddb2 ddb2 meiob meiob LOC102695765 LOC102695765 LOC102689318 LOC102689318 pole pole LOC102693973 LOC102693973 pole4 pole4 rfc5 rfc5 W5M5R0_LEPOC W5M5R0_LEPOC rpa2 rpa2 LOC102698940 LOC102698940 pole3 pole3 prkrip1 prkrip1 pold3 pold3 ccnh ccnh W5M103_LEPOC W5M103_LEPOC rfc2 rfc2 rfc4 rfc4 W5LXJ3_LEPOC W5LXJ3_LEPOC CLSPN CLSPN W5LWZ8_LEPOC W5LWZ8_LEPOC sass6 sass6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5NJQ6_LEPOCDEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (898 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
W5NF63_LEPOCF-box DNA helicase 1. (1007 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
cul4bCullin 4B; Belongs to the cullin family. (864 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
znf609Zinc finger protein 609a. (1415 aa)
cdk20Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (344 aa)
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (518 aa)
W5NAQ1_LEPOCExcision repair cross-complementation group 2. (760 aa)
fbxw12Si:ch73-142c19.1. (482 aa)
W5N8N6_LEPOCATPase family AAA domain containing 5a. (1812 aa)
W5N634_LEPOCXeroderma pigmentosum, complementation group C. (927 aa)
rfc1Replication factor C subunit 1. (1204 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (377 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
rpa3Replication protein A3. (121 aa)
LOC102695873Excision repair cross-complementation group 3. (813 aa)
LOC102688897Uncharacterized protein. (654 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (310 aa)
W5MVA4_LEPOCExcision repair cross-complementation group 5. (1082 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (382 aa)
cul4aCullin 4A; Belongs to the cullin family. (755 aa)
xpaXeroderma pigmentosum, complementation group A. (280 aa)
ZNF608Zinc finger protein 608. (1469 aa)
bivmBasic, immunoglobulin-like variable motif containing. (512 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (357 aa)
chrac1Chromatin accessibility complex subunit 1. (116 aa)
W5MM08_LEPOCExcision repair cross-complementation group 8. (393 aa)
ercc4Excision repair cross-complementation group 4. (637 aa)
LOC107075828BSD domain-containing protein. (170 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
ercc1Excision repair cross-complementation group 1. (418 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (348 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (301 aa)
W5LV61_LEPOCDamage-specific DNA binding protein 1. (1044 aa)
ddb2Damage-specific DNA binding protein 2. (506 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
LOC102695765General transcription factor IIH subunit. (392 aa)
LOC102689318Excision repair cross-complementation group 6. (1446 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2298 aa)
LOC102693973RAD23 homolog A, nucleotide excision repair protein b. (404 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (135 aa)
rfc5Replication factor C (activator 1) 5. (367 aa)
W5M5R0_LEPOCPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (168 aa)
rpa2Replication protein A2. (277 aa)
LOC102698940Centrin 4. (171 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
prkrip1PRKR interacting protein 1. (188 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
ccnhCyclin H; Belongs to the cyclin family. (322 aa)
W5M103_LEPOCDNA ligase. (1030 aa)
rfc2Replication factor C (activator 1) 2. (358 aa)
rfc4Replication factor C (activator 1) 4. (359 aa)
W5LXJ3_LEPOCDNA_pol_B domain-containing protein. (97 aa)
CLSPNClaspin. (1303 aa)
W5LWZ8_LEPOCDEAD_2 domain-containing protein. (153 aa)
sass6SAS-6 centriolar assembly protein. (654 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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