STRINGSTRING
pold3 pold3 PTGDR2 PTGDR2 babam2 babam2 slc4a1ap slc4a1ap W5NKI1_LEPOC W5NKI1_LEPOC W5NK64_LEPOC W5NK64_LEPOC W5NK63_LEPOC W5NK63_LEPOC clg8h12orf66 clg8h12orf66 W5NJN4_LEPOC W5NJN4_LEPOC mcfd2 mcfd2 unc93a unc93a W5NFG6_LEPOC W5NFG6_LEPOC W5NEB6_LEPOC W5NEB6_LEPOC pold2 pold2 blm blm rad51b rad51b W5N963_LEPOC W5N963_LEPOC W5N933_LEPOC W5N933_LEPOC brcc3 brcc3 atrx atrx LOC102693478 LOC102693478 N4BP2 N4BP2 rad51 rad51 knl1 knl1 cnp cnp XRCC2 XRCC2 W5N3D9_LEPOC W5N3D9_LEPOC W5N2Q8_LEPOC W5N2Q8_LEPOC helq helq topbp1 topbp1 stn1 stn1 dmc1 dmc1 LOC102683235 LOC102683235 recql5 recql5 W5N048_LEPOC W5N048_LEPOC rpa3 rpa3 eme1 eme1 sem1 sem1 rad50 rad50 W5MW35_LEPOC W5MW35_LEPOC LOC102688897 LOC102688897 fsbp fsbp W5MUV7_LEPOC W5MUV7_LEPOC pwwp2a pwwp2a W5MNP4_LEPOC W5MNP4_LEPOC n4bp2l2 n4bp2l2 W5MNK3_LEPOC W5MNK3_LEPOC abraxas2 abraxas2 W5LVJ9_LEPOC W5LVJ9_LEPOC W5LVL5_LEPOC W5LVL5_LEPOC W5LVS5_LEPOC W5LVS5_LEPOC W5LW14_LEPOC W5LW14_LEPOC W5LWD2_LEPOC W5LWD2_LEPOC W5LWH6_LEPOC W5LWH6_LEPOC sass6 sass6 W5LWP3_LEPOC W5LWP3_LEPOC W5LWT0_LEPOC W5LWT0_LEPOC W5LWU1_LEPOC W5LWU1_LEPOC W5LX14_LEPOC W5LX14_LEPOC W5LXJ3_LEPOC W5LXJ3_LEPOC mus81 mus81 W5LYE0_LEPOC W5LYE0_LEPOC W5LZC5_LEPOC W5LZC5_LEPOC W5LZK6_LEPOC W5LZK6_LEPOC W5M0D4_LEPOC W5M0D4_LEPOC RTEL1 RTEL1 RBBP8 RBBP8 rad51d rad51d W5M1X9_LEPOC W5M1X9_LEPOC EME2 EME2 prkrip1 prkrip1 W5M3C4_LEPOC W5M3C4_LEPOC babam1 babam1 rpa2 rpa2 W5M5Q6_LEPOC W5M5Q6_LEPOC W5M5R0_LEPOC W5M5R0_LEPOC W5M5U5_LEPOC W5M5U5_LEPOC W5M6C2_LEPOC W5M6C2_LEPOC rad54l rad54l pif1 pif1 bard1 bard1 ficd ficd top3a top3a W5MCG4_LEPOC W5MCG4_LEPOC meiob meiob SUGP1 SUGP1 sap130 sap130 W5MEE1_LEPOC W5MEE1_LEPOC W5MEG4_LEPOC W5MEG4_LEPOC MPHOSPH9 MPHOSPH9 W5MEQ9_LEPOC W5MEQ9_LEPOC W5MFK0_LEPOC W5MFK0_LEPOC rpa1 rpa1 recql4 recql4 mre11 mre11 W5MMJ0_LEPOC W5MMJ0_LEPOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
PTGDR2Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
babam2BRISC and BRCA1 A complex member 2. (386 aa)
slc4a1apSolute carrier family 4 member 1 adaptor protein. (765 aa)
W5NKI1_LEPOCSingle-stranded DNA binding protein 1. (76 aa)
W5NK64_LEPOCUncharacterized protein. (133 aa)
W5NK63_LEPOCUncharacterized protein. (163 aa)
clg8h12orf66Si:ch211-125a15.1. (448 aa)
W5NJN4_LEPOCMicrocephalin 1. (839 aa)
mcfd2Multiple coagulation factor deficiency 2. (158 aa)
unc93aUnc-93 homolog A. (465 aa)
W5NFG6_LEPOCUncharacterized protein. (176 aa)
W5NEB6_LEPOCReverse transcriptase domain-containing protein. (596 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
blmBLM RecQ like helicase. (1481 aa)
rad51bRAD51 paralog B. (384 aa)
W5N963_LEPOCUncharacterized protein. (205 aa)
W5N933_LEPOCReverse transcriptase domain-containing protein. (704 aa)
brcc3BRCA1/BRCA2-containing complex, subunit 3. (262 aa)
atrxATRX chromatin remodeler, like. (2427 aa)
LOC102693478G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (330 aa)
N4BP2NEDD4 binding protein 2. (1724 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (341 aa)
knl1Knl1_RWD_C domain-containing protein. (2485 aa)
cnp2',3'-cyclic nucleotide 3' phosphodiesterase. (448 aa)
XRCC2X-ray repair cross complementing 2. (285 aa)
W5N3D9_LEPOCUncharacterized protein. (465 aa)
W5N2Q8_LEPOCAbraxas 1, BRCA1 A complex subunit. (411 aa)
helqHelicase, POLQ like. (1066 aa)
topbp1DNA topoisomerase II binding protein 1. (1514 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (377 aa)
dmc1Uncharacterized protein. (94 aa)
LOC102683235Synaptonemal complex protein 3. (183 aa)
recql5RecQ helicase-like 5. (1025 aa)
W5N048_LEPOCUncharacterized protein. (1423 aa)
rpa3Replication protein A3. (121 aa)
eme1Essential meiotic structure-specific endonuclease 1. (590 aa)
sem1SEM1 26S proteasome complex subunit. (70 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
W5MW35_LEPOCNibrin. (846 aa)
LOC102688897Uncharacterized protein. (654 aa)
fsbpRAD54 homolog B. (940 aa)
W5MUV7_LEPOCDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (348 aa)
pwwp2aPWWP domain containing 2A. (672 aa)
W5MNP4_LEPOCUncharacterized protein. (179 aa)
n4bp2l2Uncharacterized protein. (254 aa)
W5MNK3_LEPOCTower domain-containing protein. (871 aa)
abraxas2Abraxas 2, BRISC complex subunit. (444 aa)
W5LVJ9_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (461 aa)
W5LVL5_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (858 aa)
W5LVS5_LEPOCUncharacterized protein. (134 aa)
W5LW14_LEPOCHelitron_like_N domain-containing protein. (390 aa)
W5LWD2_LEPOCHELICc2 domain-containing protein. (80 aa)
W5LWH6_LEPOCReverse transcriptase domain-containing protein. (823 aa)
sass6SAS-6 centriolar assembly protein. (654 aa)
W5LWP3_LEPOCUncharacterized protein. (178 aa)
W5LWT0_LEPOCReverse transcriptase domain-containing protein. (604 aa)
W5LWU1_LEPOCHELICc2 domain-containing protein. (158 aa)
W5LX14_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (792 aa)
W5LXJ3_LEPOCDNA_pol_B domain-containing protein. (97 aa)
mus81MUS81 structure-specific endonuclease subunit. (616 aa)
W5LYE0_LEPOCPITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1. (93 aa)
W5LZC5_LEPOCRAD51 paralog C. (374 aa)
W5LZK6_LEPOCNon-specific serine/threonine protein kinase. (3061 aa)
W5M0D4_LEPOCSMC5-SMC6 complex localization factor 1. (858 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1117 aa)
RBBP8Uncharacterized protein. (865 aa)
rad51dDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (336 aa)
W5M1X9_LEPOCDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (863 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (472 aa)
prkrip1PRKR interacting protein 1. (188 aa)
W5M3C4_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (333 aa)
babam1BRISC and BRCA1 A complex member 1. (347 aa)
rpa2Replication protein A2. (277 aa)
W5M5Q6_LEPOCUncharacterized protein. (209 aa)
W5M5R0_LEPOCPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (168 aa)
W5M5U5_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. (263 aa)
W5M6C2_LEPOCUncharacterized protein. (318 aa)
rad54lRAD54 like. (758 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (659 aa)
bard1BRCA1 associated RING domain 1. (825 aa)
ficdFIC domain containing. (452 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (803 aa)
W5MCG4_LEPOCBRCA1 interacting protein C-terminal helicase 1. (1083 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
SUGP1SURP and G-patch domain containing 1. (573 aa)
sap130Sin3A-associated protein a. (1060 aa)
W5MEE1_LEPOCPALB2_WD40 domain-containing protein. (122 aa)
W5MEG4_LEPOCUncharacterized protein. (536 aa)
MPHOSPH9M-phase phosphoprotein 9. (1223 aa)
W5MEQ9_LEPOCLeucine rich adaptor protein 1. (301 aa)
W5MFK0_LEPOCDEAD (Asp-Glu-Ala-Asp) box polypeptide 52. (527 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
recql4RecQ helicase-like 4. (1459 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (725 aa)
W5MMJ0_LEPOCUnc-93 homolog B1, TLR signaling regulator. (305 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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