STRINGSTRING
n4bp2l2 n4bp2l2 PTGDR2 PTGDR2 rmi1 rmi1 W5NK42_LEPOC W5NK42_LEPOC W5NJJ6_LEPOC W5NJJ6_LEPOC fancl fancl W5NFE6_LEPOC W5NFE6_LEPOC fanci fanci blm blm LOC102695381 LOC102695381 W5N8T9_LEPOC W5N8T9_LEPOC W5N8A0_LEPOC W5N8A0_LEPOC LOC102696624 LOC102696624 LOC102693478 LOC102693478 N4BP2 N4BP2 faap100 faap100 rad51 rad51 cnp cnp W5N4H5_LEPOC W5N4H5_LEPOC W5N104_LEPOC W5N104_LEPOC W5N048_LEPOC W5N048_LEPOC FANCM FANCM rpa3 rpa3 eme1 eme1 fancd2 fancd2 LOC102688897 LOC102688897 fancb fancb wdr48 wdr48 ube2t ube2t W5MSG4_LEPOC W5MSG4_LEPOC W5MPN7_LEPOC W5MPN7_LEPOC LOC102691293 LOC102691293 W5MNP4_LEPOC W5MNP4_LEPOC W5MNK3_LEPOC W5MNK3_LEPOC atr atr ercc4 ercc4 hes4 hes4 nutf2 nutf2 W5MHY9_LEPOC W5MHY9_LEPOC CENPS CENPS usp1 usp1 rpa1 rpa1 ercc1 ercc1 tent2 tent2 W5MET7_LEPOC W5MET7_LEPOC W5MEG4_LEPOC W5MEG4_LEPOC W5MEE1_LEPOC W5MEE1_LEPOC W5MDZ8_LEPOC W5MDZ8_LEPOC hes2 hes2 W5MCG4_LEPOC W5MCG4_LEPOC HES1 HES1 top3a top3a mlh1 mlh1 LOC102694699 LOC102694699 rmi2 rmi2 W5M950_LEPOC W5M950_LEPOC W5M924_LEPOC W5M924_LEPOC poli poli W5M613_LEPOC W5M613_LEPOC rpa2 rpa2 FANCA FANCA W5M4D7_LEPOC W5M4D7_LEPOC EME2 EME2 W5M2K0_LEPOC W5M2K0_LEPOC W5M1X9_LEPOC W5M1X9_LEPOC W5M0X5_LEPOC W5M0X5_LEPOC RTEL1 RTEL1 W5LZL8_LEPOC W5LZL8_LEPOC W5LZC5_LEPOC W5LZC5_LEPOC W5LYE0_LEPOC W5LYE0_LEPOC mus81 mus81 W5LWU1_LEPOC W5LWU1_LEPOC sass6 sass6 W5LWD2_LEPOC W5LWD2_LEPOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
n4bp2l2Uncharacterized protein. (254 aa)
PTGDR2Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (627 aa)
W5NK42_LEPOCREV3 like, DNA directed polymerase zeta catalytic subunit. (3084 aa)
W5NJJ6_LEPOCMicrotubule associated monooxygenase, calponin and LIM domain containing 3a. (2273 aa)
fanclFA complementation group L. (373 aa)
W5NFE6_LEPOCPolymerase (DNA directed), eta. (645 aa)
fanciFA complementation group I. (1329 aa)
blmBLM RecQ like helicase. (1481 aa)
LOC102695381Hairy-related 8a. (226 aa)
W5N8T9_LEPOCATR interacting protein. (763 aa)
W5N8A0_LEPOCFanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1018 aa)
LOC102696624Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (264 aa)
LOC102693478G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (330 aa)
N4BP2NEDD4 binding protein 2. (1724 aa)
faap100Si:dkey-57h18.1. (902 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (341 aa)
cnp2',3'-cyclic nucleotide 3' phosphodiesterase. (448 aa)
W5N4H5_LEPOCUncharacterized protein. (49 aa)
W5N104_LEPOCMicrotubule associated monooxygenase, calponin and LIM domain containing 1. (1219 aa)
W5N048_LEPOCUncharacterized protein. (1423 aa)
FANCMFA complementation group M. (2093 aa)
rpa3Replication protein A3. (121 aa)
eme1Essential meiotic structure-specific endonuclease 1. (590 aa)
fancd2FA complementation group D2. (1461 aa)
LOC102688897Uncharacterized protein. (654 aa)
fancbFA complementation group B. (834 aa)
wdr48WD repeat domain 48b. (679 aa)
ube2tUbiquitin-conjugating enzyme E2T (putative); Belongs to the ubiquitin-conjugating enzyme family. (197 aa)
W5MSG4_LEPOCFA complementation group C. (563 aa)
W5MPN7_LEPOCPMS1 homolog 2, mismatch repair system component. (786 aa)
LOC102691293Nuclear transport factor 2, like. (129 aa)
W5MNP4_LEPOCUncharacterized protein. (179 aa)
W5MNK3_LEPOCTower domain-containing protein. (871 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2649 aa)
ercc4Excision repair cross-complementation group 4. (637 aa)
hes4Hairy-related 9. (280 aa)
nutf2Nuclear transport factor 2. (130 aa)
W5MHY9_LEPOCFA complementation group G. (621 aa)
CENPSCentromere protein S. (140 aa)
usp1Ubiquitin carboxyl-terminal hydrolase. (808 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
ercc1Excision repair cross-complementation group 1. (418 aa)
tent2Terminal nucleotidyltransferase 2. (506 aa)
W5MET7_LEPOCPolymerase (DNA directed), theta. (2592 aa)
W5MEG4_LEPOCUncharacterized protein. (536 aa)
W5MEE1_LEPOCPALB2_WD40 domain-containing protein. (122 aa)
W5MDZ8_LEPOCPolymerase (DNA directed) kappa. (839 aa)
hes2Hes family bHLH transcription factor 2, tandem duplicate 2. (200 aa)
W5MCG4_LEPOCBRCA1 interacting protein C-terminal helicase 1. (1083 aa)
HES1Hairy-related 6. (273 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (803 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (760 aa)
LOC102694699Hairy-related 8.2. (216 aa)
rmi2RecQ mediated genome instability 2. (154 aa)
W5M950_LEPOCMicrotubule associated monooxygenase, calponin and LIM domain containing 2a. (1095 aa)
W5M924_LEPOCBMERB domain-containing protein. (179 aa)
poliPolymerase (DNA directed) iota. (737 aa)
W5M613_LEPOCTEL2, telomere maintenance 2, homolog (S. cerevisiae). (842 aa)
rpa2Replication protein A2. (277 aa)
FANCAFA complementation group A. (1407 aa)
W5M4D7_LEPOCSLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1669 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (472 aa)
W5M2K0_LEPOCPolymerase (DNA directed) nu. (728 aa)
W5M1X9_LEPOCDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (863 aa)
W5M0X5_LEPOCFA core complex associated protein 24. (222 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1117 aa)
W5LZL8_LEPOCDNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1199 aa)
W5LZC5_LEPOCRAD51 paralog C. (374 aa)
W5LYE0_LEPOCPITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1. (93 aa)
mus81MUS81 structure-specific endonuclease subunit. (616 aa)
W5LWU1_LEPOCHELICc2 domain-containing protein. (158 aa)
sass6SAS-6 centriolar assembly protein. (654 aa)
W5LWD2_LEPOCHELICc2 domain-containing protein. (80 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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