STRINGSTRING
tnfsf10 tnfsf10 W5NNT0_LEPOC W5NNT0_LEPOC LOC102689161 LOC102689161 ngf ngf jun jun map3k5 map3k5 W5NIN1_LEPOC W5NIN1_LEPOC LOC102692054 LOC102692054 W5NGW5_LEPOC W5NGW5_LEPOC parp1 parp1 LOC102686287 LOC102686287 LOC102683469 LOC102683469 LOC102686084 LOC102686084 W5NF49_LEPOC W5NF49_LEPOC W5NF13_LEPOC W5NF13_LEPOC LOC102683981 LOC102683981 CAPN9 CAPN9 W5NE85_LEPOC W5NE85_LEPOC LOC107077915 LOC107077915 aifm1 aifm1 kras kras W5NDZ4_LEPOC W5NDZ4_LEPOC apaf1 apaf1 htra4 htra4 LOC102693931 LOC102693931 akt2 akt2 W5NBL4_LEPOC W5NBL4_LEPOC W5NBK9_LEPOC W5NBK9_LEPOC W5NBB2_LEPOC W5NBB2_LEPOC tuba3e tuba3e ctsh ctsh LOC102682818 LOC102682818 eif2s1 eif2s1 map2k1 map2k1 tp53 tp53 cenpu cenpu W5N8J1_LEPOC W5N8J1_LEPOC ERN1 ERN1 W5N7Y0_LEPOC W5N7Y0_LEPOC capn3 capn3 LOC102692872 LOC102692872 W5N5X9_LEPOC W5N5X9_LEPOC LOC102688505 LOC102688505 ACTG1 ACTG1 birc5 birc5 akt1 akt1 BAK1 BAK1 bcl2 bcl2 itpr3 itpr3 casp6 casp6 W5N374_LEPOC W5N374_LEPOC casp7 casp7 nfkb1 nfkb1 ptpn13 ptpn13 mapk10 mapk10 C7orf31 C7orf31 ctsl ctsl W5MZ31_LEPOC W5MZ31_LEPOC itpr1 itpr1 W5MXX0_LEPOC W5MXX0_LEPOC LOC102697829 LOC102697829 W5MXT6_LEPOC W5MXT6_LEPOC CASP8 CASP8 LOC102695089 LOC102695089 W5MXG3_LEPOC W5MXG3_LEPOC parp3 parp3 LOC102691085 LOC102691085 pik3r1 pik3r1 fos fos faslg faslg nras nras CSDE1 CSDE1 W5MVJ6_LEPOC W5MVJ6_LEPOC gem gem LOC102691138 LOC102691138 EXOG EXOG cflar cflar diablo diablo eif2ak3 eif2ak3 nfkbia nfkbia LMNA LMNA LOC102689612 LOC102689612 lmnb1 lmnb1 LOC102696227 LOC102696227 W5MNW5_LEPOC W5MNW5_LEPOC ctso ctso LOC102693197 LOC102693197 LOC102693673 LOC102693673 LOC102692997 LOC102692997 W5MMR7_LEPOC W5MMR7_LEPOC tradd tradd W5MMP8_LEPOC W5MMP8_LEPOC LOC102694713 LOC102694713 LOC102685895 LOC102685895 W5MM91_LEPOC W5MM91_LEPOC LOC102696960 LOC102696960 W5MJU5_LEPOC W5MJU5_LEPOC W5MJ15_LEPOC W5MJ15_LEPOC LOC102685547 LOC102685547 W5MIV7_LEPOC W5MIV7_LEPOC W5MIL6_LEPOC W5MIL6_LEPOC W5MHT6_LEPOC W5MHT6_LEPOC dffa dffa traf1 traf1 LOC102698655 LOC102698655 W5MGN5_LEPOC W5MGN5_LEPOC ctsz ctsz bcl2l1 bcl2l1 fas fas LOC102694124 LOC102694124 map2k2 map2k2 sptan1 sptan1 dffb dffb W5MFB9_LEPOC W5MFB9_LEPOC pik3r3 pik3r3 birc2 birc2 LOC102687664 LOC102687664 LOC102691800 LOC102691800 W5MDE2_LEPOC W5MDE2_LEPOC fadd fadd bax bax rrad rrad actb actb gadd45a gadd45a chuk chuk pik3cb pik3cb W5MA44_LEPOC W5MA44_LEPOC W5M9T6_LEPOC W5M9T6_LEPOC LOC102697123 LOC102697123 endog endog TUBA1C TUBA1C mapk8 mapk8 W5M8L4_LEPOC W5M8L4_LEPOC dab2ip dab2ip pdpk1 pdpk1 lmnb2 lmnb2 map3k6 map3k6 ctsd ctsd W5M241_LEPOC W5M241_LEPOC mapk1 mapk1 W5M1F3_LEPOC W5M1F3_LEPOC casp9 casp9 LOC102682536 LOC102682536 pik3r2 pik3r2 W5M000_LEPOC W5M000_LEPOC LOC102685634 LOC102685634 LOC102695888 LOC102695888 W5LZK6_LEPOC W5LZK6_LEPOC LOC102684903 LOC102684903 pik3ca pik3ca traf2 traf2 gadd45b gadd45b ctsb ctsb hras hras LOC102696687 LOC102696687 ntrk1 ntrk1 W5LVZ4_LEPOC W5LVZ4_LEPOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tnfsf10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (291 aa)
W5NNT0_LEPOCTubulin_C domain-containing protein. (189 aa)
LOC102689161JunE proto-oncogene, AP-1 transcription factor subunit. (349 aa)
ngfNerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (233 aa)
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (322 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1376 aa)
W5NIN1_LEPOCBH3 interacting domain death agonist. (185 aa)
LOC102692054Si:ch211-202f3.3; Belongs to the peptidase C2 family. (708 aa)
W5NGW5_LEPOCV-rel avian reticuloendotheliosis viral oncogene homolog. (605 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1009 aa)
LOC102686287Calpain 2, (m/II) large subunit, like; Belongs to the peptidase C2 family. (709 aa)
LOC102683469Calpain 8; Belongs to the peptidase C2 family. (700 aa)
LOC102686084Calpain 2, (m/II) large subunit a; Belongs to the peptidase C2 family. (712 aa)
W5NF49_LEPOCCalpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (711 aa)
W5NF13_LEPOCInhibitor of nuclear factor kappa B kinase subunit beta. (744 aa)
LOC102683981Tumor necrosis factor receptor superfamily, member a. (411 aa)
CAPN9Calpain 9; Belongs to the peptidase C2 family. (689 aa)
W5NE85_LEPOCNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (469 aa)
LOC107077915TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (298 aa)
aifm1Apoptosis inducing factor mitochondrion associated 1. (738 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
W5NDZ4_LEPOCInositol 1,4,5-trisphosphate receptor, type 2. (2696 aa)
apaf1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1261 aa)
htra4HtrA serine peptidase 4. (480 aa)
LOC102693931Uncharacterized protein; Belongs to the peptidase C14A family. (264 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
W5NBL4_LEPOCCalpain 12; Belongs to the peptidase C2 family. (709 aa)
W5NBK9_LEPOCUncharacterized protein; Belongs to the peptidase C14A family. (328 aa)
W5NBB2_LEPOCX-linked inhibitor of apoptosis. (267 aa)
tuba3eTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (331 aa)
LOC102682818Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (653 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha a. (316 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
cenpuUncharacterized protein. (465 aa)
W5N8J1_LEPOCCaspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (263 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
W5N7Y0_LEPOCZgc:158659; Belongs to the PI3/PI4-kinase family. (902 aa)
capn3Calpain 3a, (p94); Belongs to the peptidase C2 family. (819 aa)
LOC102692872Uncharacterized protein. (584 aa)
W5N5X9_LEPOCReceptor (TNFRSF)-interacting serine-threonine kinase 1, like. (635 aa)
LOC102688505Lamin L3; Belongs to the intermediate filament family. (593 aa)
ACTG1Uncharacterized protein. (434 aa)
birc5Baculoviral IAP repeat containing 5a. (152 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
BAK1BCL2 antagonist/killer 1. (216 aa)
bcl2BCL2 apoptosis regulator b. (231 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2667 aa)
casp6Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (301 aa)
W5N374_LEPOCMitogen-activated protein kinase kinase kinase 14a. (784 aa)
casp7Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (318 aa)
nfkb1Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (987 aa)
ptpn13Protein tyrosine phosphatase non-receptor type 13. (2573 aa)
mapk10Mitogen-activated protein kinase. (469 aa)
C7orf31Chromosome 7 open reading frame 31. (486 aa)
ctslSi:dkey-26g8.5; Belongs to the peptidase C1 family. (341 aa)
W5MZ31_LEPOCActivating transcription factor 4b. (411 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1b. (2772 aa)
W5MXX0_LEPOCPoly [ADP-ribose] polymerase. (1701 aa)
LOC102697829Uncharacterized protein; Belongs to the peptidase C14A family. (474 aa)
W5MXT6_LEPOCCaspase 8; Belongs to the peptidase C14A family. (552 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (543 aa)
LOC102695089Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
W5MXG3_LEPOCTubulin, alpha 8 like 3; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (573 aa)
parp3Poly [ADP-ribose] polymerase. (516 aa)
LOC102691085V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (383 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
fosV-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (383 aa)
faslgFas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (252 aa)
nrasNRAS proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain containing E1. (900 aa)
W5MVJ6_LEPOCTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
gemGTP binding protein overexpressed in skeletal muscle. (240 aa)
LOC102691138Mitogen-activated protein kinase. (423 aa)
EXOGExo/endonuclease G. (361 aa)
cflarCASP8 and FADD-like apoptosis regulator a; Belongs to the peptidase C14A family. (471 aa)
diabloDiablo, IAP-binding mitochondrial protein b. (243 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1095 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (316 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (278 aa)
LOC102689612Uncharacterized protein. (519 aa)
lmnb1Lamin B1; Belongs to the intermediate filament family. (590 aa)
LOC102696227Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (455 aa)
W5MNW5_LEPOCHtrA serine peptidase 1b. (492 aa)
ctsoCathepsin O; Belongs to the peptidase C1 family. (355 aa)
LOC102693197Growth arrest and DNA-damage-inducible, gamma a. (172 aa)
LOC102693673Ribosomal_L7Ae domain-containing protein. (161 aa)
LOC102692997Growth arrest and DNA damage inducible gamma. (200 aa)
W5MMR7_LEPOCCathepsin K; Belongs to the peptidase C1 family. (341 aa)
traddTnfrsf1a-associated via death domain. (304 aa)
W5MMP8_LEPOCUncharacterized protein; Belongs to the peptidase C1 family. (336 aa)
LOC102694713Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (343 aa)
LOC102685895MCL1 apoptosis regulator, BCL2 family member b. (293 aa)
W5MM91_LEPOCProtein kinase domain-containing protein. (231 aa)
LOC102696960Uncharacterized protein. (159 aa)
W5MJU5_LEPOCCathepsin C; Belongs to the peptidase C1 family. (467 aa)
W5MJ15_LEPOCPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1075 aa)
LOC102685547Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
W5MIV7_LEPOCDeath domain-containing protein. (337 aa)
W5MIL6_LEPOCHermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1013 aa)
W5MHT6_LEPOCRAS (RAD and GEM)-like GTP-binding 1. (301 aa)
dffaDNA fragmentation factor, alpha polypeptide. (319 aa)
traf1TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (560 aa)
LOC102698655Granzyme 3, tandem duplicate 4; Belongs to the peptidase S1 family. (278 aa)
W5MGN5_LEPOCUncharacterized protein. (596 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (312 aa)
bcl2l1BCL2 like 1. (222 aa)
fasUncharacterized protein. (306 aa)
LOC102694124Uncharacterized protein. (579 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (400 aa)
sptan1Spectrin alpha, non-erythrocytic 1. (2503 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (336 aa)
W5MFB9_LEPOCDNA-damage-inducible transcript 3. (262 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (739 aa)
birc2Baculoviral IAP repeat containing 2. (644 aa)
LOC102687664Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (259 aa)
LOC102691800Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
W5MDE2_LEPOCCathepsin L.1; Belongs to the peptidase C1 family. (330 aa)
faddFas associated via death domain. (194 aa)
baxZgc:153993. (206 aa)
rradRas-related associated with diabetes. (310 aa)
actbActin, beta 1. (377 aa)
gadd45aGrowth arrest and DNA-damage-inducible, alpha, a. (159 aa)
chukComponent of inhibitor of nuclear factor kappa B kinase complex. (763 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
W5MA44_LEPOCSeptin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (319 aa)
W5M9T6_LEPOCUncharacterized protein. (441 aa)
LOC102697123Uncharacterized protein; Belongs to the peptidase C1 family. (344 aa)
endogEndonuclease. (311 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
W5M8L4_LEPOCUncharacterized protein. (2423 aa)
dab2ipDAB2 interacting protein a. (1249 aa)
pdpk13-phosphoinositide dependent protein kinase 1a. (558 aa)
lmnb2Lamin B2; Belongs to the intermediate filament family. (609 aa)
map3k6Si:ch211-1i11.3. (1328 aa)
ctsdCathepsin D; Belongs to the peptidase A1 family. (398 aa)
W5M241_LEPOCSi:dkey-33c12.12. (625 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
W5M1F3_LEPOCCathepsin F; Belongs to the peptidase C1 family. (418 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (445 aa)
LOC102682536Zgc:63587; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (381 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (729 aa)
W5M000_LEPOCCathepsin 12; Belongs to the peptidase C1 family. (367 aa)
LOC102685634Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (308 aa)
LOC102695888TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (571 aa)
W5LZK6_LEPOCNon-specific serine/threonine protein kinase. (3061 aa)
LOC102684903Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (471 aa)
pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1087 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (513 aa)
gadd45bGrowth arrest and DNA-damage-inducible, beta a. (174 aa)
ctsbCathepsin Ba; Belongs to the peptidase C1 family. (331 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC102696687Uncharacterized protein. (121 aa)
ntrk1Tyrosine-protein kinase receptor. (791 aa)
W5LVZ4_LEPOCPoly [ADP-ribose] polymerase. (480 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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