STRINGSTRING
myc myc W5LW76_LEPOC W5LW76_LEPOC W5LWA2_LEPOC W5LWA2_LEPOC LOC102694913 LOC102694913 LOC102699190 LOC102699190 hras hras W5LXF4_LEPOC W5LXF4_LEPOC W5LXI5_LEPOC W5LXI5_LEPOC gadd45b gadd45b W5LXP7_LEPOC W5LXP7_LEPOC gata4 gata4 chek1 chek1 W5LYD5_LEPOC W5LYD5_LEPOC pik3ca pik3ca W5LYX0_LEPOC W5LYX0_LEPOC W5LZG9_LEPOC W5LZG9_LEPOC W5LZK6_LEPOC W5LZK6_LEPOC LOC102685634 LOC102685634 pik3r2 pik3r2 gata6 gata6 mras mras MAP2K3 MAP2K3 mapk1 mapk1 rbbp4 rbbp4 tgfbr2 tgfbr2 nfatc2 nfatc2 W5M3M3_LEPOC W5M3M3_LEPOC ets1 ets1 LOC102695098 LOC102695098 LOC102692092 LOC102692092 W5M558_LEPOC W5M558_LEPOC ccna2 ccna2 tsc2 tsc2 rras2 rras2 chek2 chek2 cdk4 cdk4 lin37 lin37 CDK2 CDK2 trpv4 trpv4 hipk3 hipk3 pik3cb pik3cb gadd45a gadd45a vdac2 vdac2 W5MBV7_LEPOC W5MBV7_LEPOC rrad rrad ccnd1 ccnd1 tprg1 tprg1 tprg1l tprg1l E2F2 E2F2 ccne1 ccne1 LOC102697582 LOC102697582 pik3r3 pik3r3 W5MFH6_LEPOC W5MFH6_LEPOC map2k2 map2k2 CALML6 CALML6 pten pten e2f4 e2f4 mtor mtor ccne2 ccne2 W5MHT6_LEPOC W5MHT6_LEPOC cdk1 cdk1 W5MJ15_LEPOC W5MJ15_LEPOC rbl2 rbl2 W5MK52_LEPOC W5MK52_LEPOC rad9b rad9b PPP1CC PPP1CC rbl1 rbl1 rbbp7 rbbp7 mre11 mre11 rhebl1 rhebl1 nfatc1 nfatc1 atr atr ppid ppid nfatc3 nfatc3 LOC102692997 LOC102692997 LOC102693673 LOC102693673 LOC102693197 LOC102693197 W5MNX2_LEPOC W5MNX2_LEPOC W5MPI1_LEPOC W5MPI1_LEPOC mcu mcu W5MQ86_LEPOC W5MQ86_LEPOC LOC102693076 LOC102693076 foxo1 foxo1 rb1 rb1 e2f3 e2f3 CALM1 CALM1 W5MTY5_LEPOC W5MTY5_LEPOC W5MTZ4_LEPOC W5MTZ4_LEPOC crygn crygn rheb rheb gem gem vdac1 vdac1 W5MW35_LEPOC W5MW35_LEPOC rad50 rad50 CSDE1 CSDE1 nras nras ccnb1 ccnb1 pik3r1 pik3r1 W5MWY2_LEPOC W5MWY2_LEPOC W5MX33_LEPOC W5MX33_LEPOC tgfb3 tgfb3 lin54 lin54 tgfbr1 tgfbr1 cdk6 cdk6 lin52 lin52 itpr1 itpr1 LOC102695970 LOC102695970 LOC102698741 LOC102698741 sirt1 sirt1 PPP3CA PPP3CA sqstm1 sqstm1 PPP3CB PPP3CB BTRC BTRC rad1 rad1 nfkb1 nfkb1 RASSF5 RASSF5 mapkapk2 mapkapk2 MCUB MCUB SMAD2 SMAD2 itpr3 itpr3 cdkn1a cdkn1a W5N4D7_LEPOC W5N4D7_LEPOC CDKN2B CDKN2B akt1 akt1 LOC102691822 LOC102691822 trpm7 trpm7 map2k6 map2k6 igfbp3 igfbp3 HUS1 HUS1 W5N700_LEPOC W5N700_LEPOC LOC102684715 LOC102684715 CXCL8 CXCL8 CXCL8-2 CXCL8-2 cdkn2b cdkn2b capn3 capn3 W5N7Y0_LEPOC W5N7Y0_LEPOC LOC102685390 LOC102685390 W5N875_LEPOC W5N875_LEPOC slc25a4 slc25a4 LOC102690243 LOC102690243 tp53 tp53 map2k1 map2k1 smad3 smad3 W5N977_LEPOC W5N977_LEPOC zfp36l1 zfp36l1 serpine1 serpine1 W5N9Y4_LEPOC W5N9Y4_LEPOC ccnb3 ccnb3 LOC102698937 LOC102698937 LOC102695056 LOC102695056 W5NBL4_LEPOC W5NBL4_LEPOC W5NBP5_LEPOC W5NBP5_LEPOC akt2 akt2 HIPK4 HIPK4 calm1 calm1 W5NDN2_LEPOC W5NDN2_LEPOC W5NDZ4_LEPOC W5NDZ4_LEPOC kras kras W5NE85_LEPOC W5NE85_LEPOC ppp3cc ppp3cc CAPN9 CAPN9 W5NEL3_LEPOC W5NEL3_LEPOC W5NF16_LEPOC W5NF16_LEPOC W5NF49_LEPOC W5NF49_LEPOC LOC102686084 LOC102686084 LOC102683469 LOC102683469 LOC102686287 LOC102686287 lin9 lin9 tgfb2 tgfb2 ppp3r1 ppp3r1 LOC102689159 LOC102689159 W5NGW5_LEPOC W5NGW5_LEPOC W5NH41_LEPOC W5NH41_LEPOC CALM2 CALM2 LOC102692054 LOC102692054 zfp36l2 zfp36l2 foxm1 foxm1 FOXO3 FOXO3 ccnd2 ccnd2 hipk2 hipk2 traf3ip2 traf3ip2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (404 aa)
W5LW76_LEPOCSerine/threonine-protein phosphatase. (148 aa)
W5LWA2_LEPOCIg-like domain-containing protein; Belongs to the MHC class I family. (345 aa)
LOC102694913Uncharacterized protein. (319 aa)
LOC102699190Ig-like domain-containing protein. (370 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
W5LXF4_LEPOCIg-like domain-containing protein. (269 aa)
W5LXI5_LEPOCIg-like domain-containing protein. (137 aa)
gadd45bGrowth arrest and DNA-damage-inducible, beta a. (174 aa)
W5LXP7_LEPOCIg-like domain-containing protein; Belongs to the MHC class I family. (279 aa)
gata4GATA binding protein 4. (387 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
W5LYD5_LEPOCE2F transcription factor 1. (431 aa)
pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1087 aa)
W5LYX0_LEPOCTransforming growth factor beta; Belongs to the TGF-beta family. (421 aa)
W5LZG9_LEPOCV-myb avian myeloblastosis viral oncogene homolog-like 2b. (659 aa)
W5LZK6_LEPOCNon-specific serine/threonine protein kinase. (3061 aa)
LOC102685634Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (308 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (729 aa)
gata6GATA binding protein 6. (501 aa)
mrasMuscle RAS oncogene homolog. (210 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (340 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
rbbp4Retinoblastoma binding protein 4. (424 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)
nfatc2Nuclear factor of activated T cells 2a. (912 aa)
W5M3M3_LEPOCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
ets1V-ets avian erythroblastosis virus E26 oncogene homolog 1. (433 aa)
LOC102695098Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
LOC102692092TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa)
W5M558_LEPOCCrystallin, beta B3; Belongs to the beta/gamma-crystallin family. (235 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (434 aa)
tsc2TSC complex subunit 2. (1854 aa)
rras2RAS related 2. (202 aa)
chek2Checkpoint kinase 2. (518 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (305 aa)
lin37Lin-37 DREAM MuvB core complex component. (241 aa)
CDK2Cyclin dependent kinase 2. (252 aa)
trpv4Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family. (855 aa)
hipk3Homeodomain interacting protein kinase 3b. (1255 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
gadd45aGrowth arrest and DNA-damage-inducible, alpha, a. (159 aa)
vdac2Voltage-dependent anion channel 2. (292 aa)
W5MBV7_LEPOCEts variant 2. (336 aa)
rradRas-related associated with diabetes. (310 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (296 aa)
tprg1Tumor protein p63 regulated 1. (272 aa)
tprg1lTumor protein p63 regulated 1-like. (290 aa)
E2F2E2F transcription factor 2. (177 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (412 aa)
LOC102697582TSC complex subunit 1a. (1189 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (739 aa)
W5MFH6_LEPOCGATA binding protein 5. (383 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (400 aa)
CALML6Calmodulin like 6. (156 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (417 aa)
e2f4E2F transcription factor 4. (409 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (395 aa)
W5MHT6_LEPOCRAS (RAD and GEM)-like GTP-binding 1. (301 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
W5MJ15_LEPOCPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1075 aa)
rbl2Retinoblastoma-like 2 (p130). (1102 aa)
W5MK52_LEPOCIg-like domain-containing protein; Belongs to the MHC class I family. (327 aa)
rad9bRAD9 checkpoint clamp component B. (290 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
rbl1Retinoblastoma-like 1 (p107). (1071 aa)
rbbp7Retinoblastoma binding protein 4, like. (429 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (725 aa)
rhebl1Ras homolog, mTORC1 binding like 1. (184 aa)
nfatc1Nuclear factor of activated T cells 1. (940 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2649 aa)
ppidPeptidylprolyl isomerase D. (371 aa)
nfatc3Nuclear factor of activated T cells 3a. (1061 aa)
LOC102692997Growth arrest and DNA damage inducible gamma. (200 aa)
LOC102693673Ribosomal_L7Ae domain-containing protein. (161 aa)
LOC102693197Growth arrest and DNA-damage-inducible, gamma a. (172 aa)
W5MNX2_LEPOCUncharacterized protein. (298 aa)
W5MPI1_LEPOCCyclin A1; Belongs to the cyclin family. (401 aa)
mcuMitochondrial calcium uniporter. (378 aa)
W5MQ86_LEPOCIg-like domain-containing protein; Belongs to the MHC class I family. (326 aa)
LOC102693076Transmembrane phosphatase with tensin homology. (513 aa)
foxo1Forkhead box O1 b. (663 aa)
rb1Retinoblastoma 1. (932 aa)
e2f3E2F transcription factor 3. (425 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
W5MTY5_LEPOCF-box and WD repeat domain containing 11. (168 aa)
W5MTZ4_LEPOCF-box and WD repeat domain containing 11. (304 aa)
crygnCrystallin, gamma N1; Belongs to the beta/gamma-crystallin family. (186 aa)
rhebRas homolog, mTORC1 binding. (184 aa)
gemGTP binding protein overexpressed in skeletal muscle. (240 aa)
vdac1Voltage-dependent anion channel 1. (298 aa)
W5MW35_LEPOCNibrin. (846 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
CSDE1Cold shock domain containing E1. (900 aa)
nrasNRAS proto-oncogene, GTPase. (189 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (398 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
W5MWY2_LEPOCHomeodomain interacting protein kinase 1a. (1183 aa)
W5MX33_LEPOCTRAF3 interacting protein 2-like. (264 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
lin54Lin-54 DREAM MuvB core complex component. (819 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (323 aa)
lin52Lin-52 DREAM MuvB core complex component. (131 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1b. (2772 aa)
LOC102695970Mitogen-activated protein kinase. (368 aa)
LOC102698741Mitogen-activated protein kinase. (361 aa)
sirt1Sirtuin 1. (720 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
sqstm1Sequestosome 1. (440 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (603 aa)
rad1RAD1 homolog (S. pombe). (281 aa)
nfkb1Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (987 aa)
RASSF5Ras association domain family member 5. (475 aa)
mapkapk2MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (393 aa)
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (340 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2667 aa)
cdkn1aCyclin-dependent kinase inhibitor 1A. (156 aa)
W5N4D7_LEPOCSerine/threonine-protein phosphatase. (532 aa)
CDKN2BANK_REP_REGION domain-containing protein. (125 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
LOC102691822Uncharacterized protein. (133 aa)
trpm7Transient receptor potential cation channel, subfamily M, member 7. (1886 aa)
map2k6Mitogen-activated protein kinase kinase 6. (360 aa)
igfbp3Insulin-like growth factor binding protein 3. (281 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
W5N700_LEPOCUncharacterized protein. (2231 aa)
LOC102684715Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (143 aa)
CXCL8-2Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
cdkn2bCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (128 aa)
capn3Calpain 3a, (p94); Belongs to the peptidase C2 family. (819 aa)
W5N7Y0_LEPOCZgc:158659; Belongs to the PI3/PI4-kinase family. (902 aa)
LOC102685390Mitogen-activated protein kinase. (367 aa)
W5N875_LEPOCCyclin B2; Belongs to the cyclin family. (394 aa)
slc25a4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
LOC102690243Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (332 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
smad3Mothers against decapentaplegic homolog. (427 aa)
W5N977_LEPOCCalmodulin-like 4b. (161 aa)
zfp36l1Zinc finger protein 36, C3H type-like 1a. (358 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (391 aa)
W5N9Y4_LEPOCTransforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (419 aa)
LOC102698937Sb:cb81. (394 aa)
LOC102695056Zgc:162730. (370 aa)
W5NBL4_LEPOCCalpain 12; Belongs to the peptidase C2 family. (709 aa)
W5NBP5_LEPOCCyclin N-terminal domain containing 2; Belongs to the cyclin family. (388 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HIPK4Homeodomain interacting protein kinase 4; Belongs to the protein kinase superfamily. (375 aa)
calm1Uncharacterized protein; Belongs to the calmodulin family. (197 aa)
W5NDN2_LEPOCUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (304 aa)
W5NDZ4_LEPOCInositol 1,4,5-trisphosphate receptor, type 2. (2696 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
W5NE85_LEPOCNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (469 aa)
ppp3ccSerine/threonine-protein phosphatase. (514 aa)
CAPN9Calpain 9; Belongs to the peptidase C2 family. (689 aa)
W5NEL3_LEPOCMitogen-activated protein kinase 12b. (285 aa)
W5NF16_LEPOCZgc:56235. (261 aa)
W5NF49_LEPOCCalpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (711 aa)
LOC102686084Calpain 2, (m/II) large subunit a; Belongs to the peptidase C2 family. (712 aa)
LOC102683469Calpain 8; Belongs to the peptidase C2 family. (700 aa)
LOC102686287Calpain 2, (m/II) large subunit, like; Belongs to the peptidase C2 family. (709 aa)
lin9Lin-9 DREAM MuvB core complex component. (560 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
ppp3r1Protein phosphatase 3, regulatory subunit B, alpha a. (169 aa)
LOC102689159Uncharacterized protein. (118 aa)
W5NGW5_LEPOCV-rel avian reticuloendotheliosis viral oncogene homolog. (605 aa)
W5NH41_LEPOCE3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (153 aa)
LOC102692054Si:ch211-202f3.3; Belongs to the peptidase C2 family. (708 aa)
zfp36l2Uncharacterized protein. (432 aa)
foxm1Forkhead box M1. (689 aa)
FOXO3Forkhead box O3. (676 aa)
ccnd2Cyclin D2, b; Belongs to the cyclin family. (296 aa)
hipk2Homeodomain interacting protein kinase 2. (1190 aa)
traf3ip2SEFIR domain-containing protein. (539 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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