STRINGSTRING
W5LYX0_LEPOC W5LYX0_LEPOC W5LZ67_LEPOC W5LZ67_LEPOC W5LZ94_LEPOC W5LZ94_LEPOC W5LZH3_LEPOC W5LZH3_LEPOC acvr2a acvr2a inhbb inhbb W5M1U6_LEPOC W5M1U6_LEPOC mapk1 mapk1 mycl mycl tgfbr2 tgfbr2 crebbp crebbp W5M4A0_LEPOC W5M4A0_LEPOC W5M4B1_LEPOC W5M4B1_LEPOC LOC102692092 LOC102692092 gdf6 gdf6 LOC102685535 LOC102685535 LOC102690765 LOC102690765 dcc dcc bmp7 bmp7 rps6kb1 rps6kb1 pknox1 pknox1 zfyve9 zfyve9 id1 id1 W5M9A4_LEPOC W5M9A4_LEPOC W5MA79_LEPOC W5MA79_LEPOC smurf1 smurf1 nodal nodal W5MCR5_LEPOC W5MCR5_LEPOC W5MCT1_LEPOC W5MCT1_LEPOC W5MCY8_LEPOC W5MCY8_LEPOC usf2 usf2 pknox2 pknox2 LOC102686414 LOC102686414 W5MDY0_LEPOC W5MDY0_LEPOC AMHR2 AMHR2 W5MEM1_LEPOC W5MEM1_LEPOC ACVR1C ACVR1C W5MFA6_LEPOC W5MFA6_LEPOC ACVR1 ACVR1 INHBC INHBC e2f4 e2f4 rgmb rgmb ints8 ints8 W5MHF8_LEPOC W5MHF8_LEPOC LOC102687451 LOC102687451 snapin snapin W5MIF3_LEPOC W5MIF3_LEPOC fst fst W5MJN0_LEPOC W5MJN0_LEPOC bambi bambi rbl1 rbl1 NBL1 NBL1 matn4 matn4 acvr1b acvr1b gdf5 gdf5 fbn2 fbn2 smad9 smad9 ism2 ism2 chrd chrd smad1 smad1 LOC102696984 LOC102696984 W5MRH0_LEPOC W5MRH0_LEPOC pitx3 pitx3 id4 id4 MATN2 MATN2 tfdp1 tfdp1 acvr2b acvr2b pitx1 pitx1 bmpr2 bmpr2 PPP2CA PPP2CA skp1 skp1 rhoc rhoc tgfb3 tgfb3 tgfbr1 tgfbr1 LTBP2 LTBP2 ppp2cb ppp2cb myc myc LOC102682912 LOC102682912 W5N0P4_LEPOC W5N0P4_LEPOC PITX2 PITX2 W5N1U1_LEPOC W5N1U1_LEPOC inhba inhba fmod fmod bmp4 bmp4 LOC102691729 LOC102691729 ANKFN1 ANKFN1 SMAD2 SMAD2 bmpr1a bmpr1a W5N420_LEPOC W5N420_LEPOC CDKN2B CDKN2B grem1 grem1 W5N5D9_LEPOC W5N5D9_LEPOC bmpr1b bmpr1b FBN1 FBN1 bmp6 bmp6 cul1 cul1 cdkn2b cdkn2b W5N7W2_LEPOC W5N7W2_LEPOC smad6 smad6 smad3 smad3 W5N9Y4_LEPOC W5N9Y4_LEPOC LOC102685645 LOC102685645 LOC102682211 LOC102682211 rgma rgma W5NAW2_LEPOC W5NAW2_LEPOC W5NB90_LEPOC W5NB90_LEPOC W5NB98_LEPOC W5NB98_LEPOC THSD4 THSD4 LOC102688763 LOC102688763 neo1 neo1 LOC102686592 LOC102686592 tgfb2 tgfb2 LOC102686722 LOC102686722 LOC102688552 LOC102688552 ENSLOCP00000019799 ENSLOCP00000019799 LOC102688952 LOC102688952 LOC102691411 LOC102691411 LOC102683252 LOC102683252 bmp2 bmp2 W5NJ08_LEPOC W5NJ08_LEPOC id2 id2 bmp5 bmp5 W5NKU0_LEPOC W5NKU0_LEPOC gdf7 gdf7 W5NKV6_LEPOC W5NKV6_LEPOC grem2 grem2 nog nog rhob rhob LOC102696589 LOC102696589
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5LYX0_LEPOCTransforming growth factor beta; Belongs to the TGF-beta family. (421 aa)
W5LZ67_LEPOCHomeobox domain-containing protein. (290 aa)
W5LZ94_LEPOCBone morphogenetic protein 8a. (436 aa)
W5LZH3_LEPOCProtein phosphatase 2, regulatory subunit A, beta b. (600 aa)
acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
inhbbInhibin subunit beta B. (398 aa)
W5M1U6_LEPOCRho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
myclMYCL proto-oncogene, bHLH transcription factor b. (384 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)
crebbpCREB binding protein b. (2500 aa)
W5M4A0_LEPOCUncharacterized protein. (270 aa)
W5M4B1_LEPOCEGF-like domain-containing protein. (267 aa)
LOC102692092TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa)
gdf6Growth differentiation factor 6a. (410 aa)
LOC102685535TGFB-induced factor homeobox 1. (268 aa)
LOC102690765Anti-dorsalizing morphogenic protein. (395 aa)
dccDCC netrin 1 receptor. (1447 aa)
bmp7Bone morphogenetic protein 7b. (427 aa)
rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (508 aa)
pknox1Pbx/knotted 1 homeobox 1.2. (442 aa)
zfyve9Zinc finger FYVE domain-containing protein. (1263 aa)
id1Inhibitor of DNA binding 1, HLH protein. (149 aa)
W5M9A4_LEPOCTGF_BETA_2 domain-containing protein. (394 aa)
W5MA79_LEPOCFibrillin 2b. (2775 aa)
smurf1E3 ubiquitin-protein ligase. (787 aa)
nodalNodal-related 2. (371 aa)
W5MCR5_LEPOCMatrilin 1. (645 aa)
W5MCT1_LEPOCFollistatin-like 3 (secreted glycoprotein). (251 aa)
W5MCY8_LEPOCZinc finger FYVE domain-containing protein. (1519 aa)
usf2Upstream transcription factor 2, c-fos interacting. (329 aa)
pknox2Pbx/knotted 1 homeobox 2. (479 aa)
LOC102686414Inhibitor of DNA binding 3. (122 aa)
W5MDY0_LEPOCRGM domain family, member D. (442 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (461 aa)
W5MEM1_LEPOCSp1 transcription factor. (691 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
W5MFA6_LEPOCTGF_BETA_2 domain-containing protein. (507 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
INHBCInhibin subunit beta C. (383 aa)
e2f4E2F transcription factor 4. (409 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (444 aa)
ints8Integrator complex subunit 8. (1000 aa)
W5MHF8_LEPOCADAM_spacer1 domain-containing protein. (617 aa)
LOC102687451Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
snapinSNAP associated protein. (199 aa)
W5MIF3_LEPOCMothers against decapentaplegic homolog. (556 aa)
fstFollistatin a. (349 aa)
W5MJN0_LEPOCNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (492 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
rbl1Retinoblastoma-like 1 (p107). (1071 aa)
NBL1NBL1, DAN family BMP antagonist. (172 aa)
matn4Matrilin 4. (775 aa)
acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
gdf5Growth differentiation factor 5. (531 aa)
fbn2Fibrillin 2a. (2880 aa)
smad9Mothers against decapentaplegic homolog. (467 aa)
ism2Isthmin 2a. (454 aa)
chrdChordin; Belongs to the chordin family. (967 aa)
smad1Mothers against decapentaplegic homolog. (468 aa)
LOC102696984Uncharacterized protein. (867 aa)
W5MRH0_LEPOCSi:dkey-235d18.5. (804 aa)
pitx3Homeobox protein. (292 aa)
id4Inhibitor of DNA binding 4. (134 aa)
MATN2Matrilin 2. (852 aa)
tfdp1Transcription factor. (407 aa)
acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
pitx1Homeobox protein. (317 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1075 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
rhocRas homolog family member Cb. (202 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1657 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (404 aa)
LOC102682912Mothers against decapentaplegic homolog. (464 aa)
W5N0P4_LEPOCE1A binding protein p300 a. (2068 aa)
PITX2Homeobox protein. (316 aa)
W5N1U1_LEPOCFibronectin type-III domain-containing protein. (131 aa)
inhbaInhibin subunit beta Ab. (395 aa)
fmodFibromodulin b. (353 aa)
bmp4Bone morphogenetic protein 4. (401 aa)
LOC102691729Zgc:113307. (366 aa)
ANKFN1Ankyrin repeat and fibronectin type III domain containing 1. (1292 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
W5N420_LEPOCThrombospondin 1b. (1174 aa)
CDKN2BANK_REP_REGION domain-containing protein. (125 aa)
grem1Gremlin 1a, DAN family BMP antagonist. (186 aa)
W5N5D9_LEPOCMothers against decapentaplegic homolog. (547 aa)
bmpr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
FBN1Fibrillin 1. (2869 aa)
bmp6Bone morphogenetic protein 6. (431 aa)
cul1Cullin 1a; Belongs to the cullin family. (777 aa)
cdkn2bCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (128 aa)
W5N7W2_LEPOCE3 ubiquitin-protein ligase. (769 aa)
smad6Mothers against decapentaplegic homolog. (487 aa)
smad3Mothers against decapentaplegic homolog. (427 aa)
W5N9Y4_LEPOCTransforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
LOC102685645CTCK domain-containing protein. (265 aa)
LOC102682211Ras homolog gene family, member Ab. (193 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (447 aa)
W5NAW2_LEPOCRas homolog gene family, member Ab. (202 aa)
W5NB90_LEPOCUncharacterized protein. (148 aa)
W5NB98_LEPOCUncharacterized protein. (1544 aa)
THSD4Thrombospondin type 1 domain containing 4. (984 aa)
LOC102688763Bone morphogenetic protein 16. (398 aa)
neo1Neogenin 1b. (1457 aa)
LOC102686592Homeobox protein. (237 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC102686722Left-right determination factor. (364 aa)
LOC102688552TGF_BETA_2 domain-containing protein. (375 aa)
ENSLOCP00000019799annotation not available (174 aa)
LOC102688952Southpaw. (411 aa)
LOC102691411Uncharacterized protein. (187 aa)
LOC102683252Decorin; May affect the rate of fibrils formation. (359 aa)
bmp2Bone morphogenetic protein 2a. (399 aa)
W5NJ08_LEPOCLatent transforming growth factor beta binding protein 1. (1410 aa)
id2Inhibitor of DNA binding 2b. (135 aa)
bmp5Bone morphogenetic protein 5. (457 aa)
W5NKU0_LEPOCMatrilin 3b. (400 aa)
gdf7Growth differentiation factor 7. (417 aa)
W5NKV6_LEPOCLipid droplet associated hydrolase. (342 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (166 aa)
nogNoggin; Belongs to the noggin family. (224 aa)
rhobUncharacterized protein. (196 aa)
LOC102696589Noggin; Belongs to the noggin family. (210 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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