STRINGSTRING
W5N7Y0_LEPOC W5N7Y0_LEPOC W5LVK5_LEPOC W5LVK5_LEPOC LOC102695896 LOC102695896 W5LW76_LEPOC W5LW76_LEPOC hras hras pik3ca pik3ca mknk2 mknk2 bud23 bud23 SH2B2 SH2B2 W5M045_LEPOC W5M045_LEPOC pik3r2 pik3r2 prkar1b prkar1b alkbh4 alkbh4 PRKAB2 PRKAB2 mapk1 mapk1 W5M255_LEPOC W5M255_LEPOC ptpn1 ptpn1 W5M3M3_LEPOC W5M3M3_LEPOC W5M558_LEPOC W5M558_LEPOC tsc2 tsc2 pde3b pde3b flot2 flot2 pdpk1 pdpk1 rps6kb1 rps6kb1 mapk8 mapk8 mknk1 mknk1 myo9b myo9b insr insr phkg1 phkg1 W5M9W5_LEPOC W5M9W5_LEPOC rapgef1 rapgef1 pik3cb pik3cb acacb acacb rrad rrad acaca acaca cblb cblb phkb phkb LOC102697582 LOC102697582 prkcz prkcz pik3r3 pik3r3 W5MF15_LEPOC W5MF15_LEPOC W5MF18_LEPOC W5MF18_LEPOC map2k2 map2k2 ppp1r3c ppp1r3c CALML6 CALML6 mtor mtor crkl crkl W5MHT6_LEPOC W5MHT6_LEPOC W5MJ15_LEPOC W5MJ15_LEPOC gsk3b gsk3b W5MJN0_LEPOC W5MJN0_LEPOC pck1 pck1 W5MJT7_LEPOC W5MJT7_LEPOC prkci prkci trip10 trip10 PPP1CC PPP1CC INPP5A INPP5A phka2 phka2 W5ML50_LEPOC W5ML50_LEPOC prkag1 prkag1 shc1 shc1 rhebl1 rhebl1 W5MM02_LEPOC W5MM02_LEPOC G6PC2 G6PC2 prkacb prkacb W5MQL4_LEPOC W5MQL4_LEPOC prkaa2 prkaa2 foxo1 foxo1 CALM1 CALM1 LOC102687955 LOC102687955 HK1 HK1 LOC102697157 LOC102697157 LOC102694874 LOC102694874 LOC102695073 LOC102695073 W5MUU9_LEPOC W5MUU9_LEPOC W5MV05_LEPOC W5MV05_LEPOC crygn crygn rheb rheb LOC102691138 LOC102691138 gem gem CSDE1 CSDE1 nras nras pik3r1 pik3r1 prkag3 prkag3 W5MZ39_LEPOC W5MZ39_LEPOC ttc33 ttc33 grap2 grap2 LOC102682959 LOC102682959 LOC102683163 LOC102683163 W5N0N9_LEPOC W5N0N9_LEPOC ppp1r3g ppp1r3g SHC3 SHC3 sos2 sos2 eif4e1b eif4e1b W5N1W4_LEPOC W5N1W4_LEPOC pygl pygl mapk10 mapk10 W5N2Z1_LEPOC W5N2Z1_LEPOC eif4e eif4e g6pc g6pc W5N3E5_LEPOC W5N3E5_LEPOC fasn fasn ppargc1a ppargc1a prkar1a prkar1a prkag2 prkag2 akt1 akt1 LOC102691822 LOC102691822 exoc7 exoc7 g6pc3 g6pc3 SHC4 SHC4 PTPRD PTPRD grb2 grb2 W5N7F7_LEPOC W5N7F7_LEPOC W5N8R3_LEPOC W5N8R3_LEPOC W5N8T4_LEPOC W5N8T4_LEPOC SLC2A4 SLC2A4 map2k1 map2k1 W5N977_LEPOC W5N977_LEPOC raf1 raf1 LOC102687735 LOC102687735 W5NAS5_LEPOC W5NAS5_LEPOC W5NAT0_LEPOC W5NAT0_LEPOC W5NAU5_LEPOC W5NAU5_LEPOC hdac8 hdac8 W5NBC2_LEPOC W5NBC2_LEPOC akt2 akt2 calm1 calm1 W5NCP1_LEPOC W5NCP1_LEPOC myo9a myo9a W5ND01_LEPOC W5ND01_LEPOC gck gck LOC102682643 LOC102682643 LOC102698058 LOC102698058 kras kras gys2 gys2 W5NE85_LEPOC W5NE85_LEPOC LOC102684581 LOC102684581 W5NF13_LEPOC W5NF13_LEPOC elk3 elk3 socs2 socs2 prkar2b prkar2b BMT2 BMT2 W5NG59_LEPOC W5NG59_LEPOC LOC102689159 LOC102689159 LOC102689970 LOC102689970 braf braf CALM2 CALM2 pygb pygb W5NLK8_LEPOC W5NLK8_LEPOC irs4 irs4 W5NLZ3_LEPOC W5NLZ3_LEPOC W5NM29_LEPOC W5NM29_LEPOC socs4 socs4 socs3 socs3 W5NMP3_LEPOC W5NMP3_LEPOC socs1 socs1 ppp1r3d ppp1r3d
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5N7Y0_LEPOCZgc:158659; Belongs to the PI3/PI4-kinase family. (902 aa)
W5LVK5_LEPOCProtein tyrosine phosphatase receptor type Sa. (1928 aa)
LOC102695896Si:dkey-61p9.11. (2108 aa)
W5LW76_LEPOCSerine/threonine-protein phosphatase. (148 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1087 aa)
mknk2MAPK interacting serine/threonine kinase 2a; Belongs to the protein kinase superfamily. (475 aa)
bud23BUD23 rRNA methyltransferase and ribosome maturation factor. (282 aa)
SH2B2SH2B adaptor protein 2. (650 aa)
W5M045_LEPOCProtein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (259 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (729 aa)
prkar1bProtein kinase, cAMP-dependent, regulatory, type I, beta. (383 aa)
alkbh4AlkB homolog 4, lysine demthylase. (271 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (273 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
W5M255_LEPOCAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (671 aa)
ptpn1Tyrosine-protein phosphatase non-receptor type. (442 aa)
W5M3M3_LEPOCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
W5M558_LEPOCCrystallin, beta B3; Belongs to the beta/gamma-crystallin family. (235 aa)
tsc2TSC complex subunit 2. (1854 aa)
pde3bPhosphodiesterase. (1094 aa)
flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (455 aa)
pdpk13-phosphoinositide dependent protein kinase 1a. (558 aa)
rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (508 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (467 aa)
myo9bMyosin IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2130 aa)
insrTyrosine-protein kinase receptor. (1365 aa)
phkg1Phosphorylase kinase, gamma 1b (muscle); Belongs to the protein kinase superfamily. (393 aa)
W5M9W5_LEPOCProtein tyrosine phosphatase receptor type Fb. (1906 aa)
rapgef1Rap guanine nucleotide exchange factor (GEF) 1a. (1224 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
acacbAcetyl-CoA carboxylase beta. (2385 aa)
rradRas-related associated with diabetes. (310 aa)
acacaAcetyl-CoA carboxylase alpha. (2356 aa)
cblbCbl proto-oncogene B, E3 ubiquitin protein ligase. (989 aa)
phkbPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1114 aa)
LOC102697582TSC complex subunit 1a. (1189 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (739 aa)
W5MF15_LEPOCTubulin-specific chaperone A; Belongs to the TBCA family. (110 aa)
W5MF18_LEPOCSHC (Src homology 2 domain containing) transforming protein 2. (594 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (400 aa)
ppp1r3cProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (320 aa)
CALML6Calmodulin like 6. (156 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (302 aa)
W5MHT6_LEPOCRAS (RAD and GEM)-like GTP-binding 1. (301 aa)
W5MJ15_LEPOCPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1075 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (420 aa)
W5MJN0_LEPOCNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (492 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (623 aa)
W5MJT7_LEPOCV-crk avian sarcoma virus CT10 oncogene homolog. (269 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
trip10Thyroid hormone receptor interactor 10b. (605 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (412 aa)
phka2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1265 aa)
W5ML50_LEPOCCarrier domain-containing protein. (2007 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (330 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
rhebl1Ras homolog, mTORC1 binding like 1. (184 aa)
W5MM02_LEPOCInositol polyphosphate phosphatase-like 1a. (1284 aa)
G6PC2Glucose-6-phosphatase catalytic subunit 2. (219 aa)
prkacbProtein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (396 aa)
W5MQL4_LEPOCSterol regulatory element binding transcription factor 1. (1179 aa)
prkaa2Non-specific serine/threonine protein kinase. (551 aa)
foxo1Forkhead box O1 b. (663 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
LOC102687955Hexokinase domain containing 1. (914 aa)
HK1Hexokinase 1. (985 aa)
LOC102697157Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (216 aa)
LOC102694874Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
LOC102695073Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (133 aa)
W5MUU9_LEPOCUncharacterized protein. (207 aa)
W5MV05_LEPOCUncharacterized protein; Belongs to the protein kinase superfamily. (344 aa)
crygnCrystallin, gamma N1; Belongs to the beta/gamma-crystallin family. (186 aa)
rhebRas homolog, mTORC1 binding. (184 aa)
LOC102691138Mitogen-activated protein kinase. (423 aa)
gemGTP binding protein overexpressed in skeletal muscle. (240 aa)
CSDE1Cold shock domain containing E1. (900 aa)
nrasNRAS proto-oncogene, GTPase. (189 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
prkag3Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (339 aa)
W5MZ39_LEPOC40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (274 aa)
ttc33Non-specific serine/threonine protein kinase. (561 aa)
grap2GRB2 related adaptor protein 2a. (290 aa)
LOC102682959Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family. (340 aa)
LOC102683163Fructose-1,6-bisphosphatase 1b; Belongs to the FBPase class 1 family. (351 aa)
W5N0N9_LEPOCSorbin and SH3 domain containing 1. (1282 aa)
ppp1r3gSi:ch211-152c8.5. (236 aa)
SHC3SHC adaptor protein 3. (634 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1341 aa)
eif4e1bEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (222 aa)
W5N1W4_LEPOCSterol regulatory element binding transcription factor 2. (1120 aa)
pyglAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (863 aa)
mapk10Mitogen-activated protein kinase. (469 aa)
W5N2Z1_LEPOCGlucose-6-phosphatase a, catalytic subunit, tandem duplicate 1. (358 aa)
eif4eEukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family. (241 aa)
g6pcGlucose-6-phosphatase a, catalytic subunit, tandem duplicate 2. (358 aa)
W5N3E5_LEPOCUncharacterized protein. (1200 aa)
fasnCoiled-coil domain containing 57. (2531 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (833 aa)
prkar1aProtein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b. (380 aa)
prkag2Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (557 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
LOC102691822Uncharacterized protein. (133 aa)
exoc7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (735 aa)
g6pc3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (350 aa)
SHC4SHC adaptor protein 4. (610 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1939 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
W5N7F7_LEPOCRegulatory associated protein of MTOR, complex 1. (1375 aa)
W5N8R3_LEPOCUncharacterized protein. (116 aa)
W5N8T4_LEPOCSorbin and SH3 domain containing 2a. (1413 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (499 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
W5N977_LEPOCCalmodulin-like 4b. (161 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase b. (686 aa)
LOC102687735A-Raf proto-oncogene, serine/threonine kinase. (627 aa)
W5NAS5_LEPOCSolute carrier family 25 member 20; Belongs to the mitochondrial carrier (TC 2.A.29) family. (305 aa)
W5NAT0_LEPOCProtein kinase, cAMP-dependent, regulatory, type II, alpha, B. (381 aa)
W5NAU5_LEPOCCBM21 domain-containing protein. (295 aa)
hdac8Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1381 aa)
W5NBC2_LEPOCETS transcription factor ELK1. (449 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
calm1Uncharacterized protein; Belongs to the calmodulin family. (197 aa)
W5NCP1_LEPOCSorbin and SH3 domain containing 3. (629 aa)
myo9aMyosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2677 aa)
W5ND01_LEPOCInositol polyphosphate-5-phosphatase L. (397 aa)
gckPhosphotransferase. (478 aa)
LOC102682643Inositol polyphosphate phosphatase-like 1b. (1226 aa)
LOC102698058Hexokinase 2. (923 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
gys2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (705 aa)
W5NE85_LEPOCNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (469 aa)
LOC102684581Si:dkey-150i13.2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
W5NF13_LEPOCInhibitor of nuclear factor kappa B kinase subunit beta. (744 aa)
elk3ETS transcription factor ELK3. (422 aa)
socs2Suppressor of cytokine signaling 2. (195 aa)
prkar2bProtein kinase cAMP-dependent type II regulatory subunit beta. (412 aa)
BMT2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (408 aa)
W5NG59_LEPOCCBM21 domain-containing protein. (1012 aa)
LOC102689159Uncharacterized protein. (118 aa)
LOC102689970Zgc:77112. (313 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (820 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (153 aa)
pygbAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (844 aa)
W5NLK8_LEPOCInsulin receptor substrate 1. (1079 aa)
irs4Insulin receptor substrate 4a. (1038 aa)
W5NLZ3_LEPOCProtein phosphatase 1 regulatory subunit. (305 aa)
W5NM29_LEPOCCBM21 domain-containing protein. (301 aa)
socs4Suppressor of cytokine signaling 4. (384 aa)
socs3Suppressor of cytokine signaling 3b. (208 aa)
W5NMP3_LEPOCInsulin receptor substrate 2b. (1069 aa)
socs1Suppressor of cytokine signaling 1a. (202 aa)
ppp1r3dProtein phosphatase 1, regulatory subunit 3Db. (268 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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