STRINGSTRING
AEH22140.1 AEH22140.1 AEH22225.1 AEH22225.1 eno eno mdh mdh AEH22497.1 AEH22497.1 AEH22499.1 AEH22499.1 AEH22502.1 AEH22502.1 AEH22599.1 AEH22599.1 AEH22600.1 AEH22600.1 AEH22738.1 AEH22738.1 fbp fbp glyA glyA apgM apgM AEH22989.1 AEH22989.1 pfkA pfkA AEH23528.1 AEH23528.1 AEH23529.1 AEH23529.1 AEH23568.1 AEH23568.1 AEH23660.1 AEH23660.1 AEH23676.1 AEH23676.1 AEH23677.1 AEH23677.1 AEH23678.1 AEH23678.1 AEH23679.1 AEH23679.1 AEH23691.1 AEH23691.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
AEH22140.1TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: sat:SYN_00123 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT. (526 aa)
AEH22225.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (811 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa)
AEH22497.1PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Putative Fe-S cluster; Dihydropteroate synthase, DHPS; KEGG: dak:DaAHT2_0824 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel. (796 aa)
AEH22499.1PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; KEGG: dak:DaAHT2_0826 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel. (402 aa)
AEH22502.1KEGG: adg:Adeg_0335 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane. (735 aa)
AEH22599.1Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1013 aa)
AEH22600.1PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tye:THEYE_A0893 nitrate-inducible formate dehydrogenase, beta subunit. (238 aa)
AEH22738.1Acetate--CoA ligase; KEGG: reh:H16_A1616 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase. (691 aa)
fbpProtein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (368 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
apgMPhosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (407 aa)
AEH22989.1PFAM: Formylmethanofuran dehydrogenase, subunit E region; KEGG: sun:SUN_1417 hypothetical protein. (242 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (448 aa)
AEH23528.1TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1013 aa)
AEH23529.1PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tye:THEYE_A0893 nitrate-inducible formate dehydrogenase, beta subunit. (238 aa)
AEH23568.1PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tye:THEYE_A1281 iron-sulfur protein. (339 aa)
AEH23660.1PFAM: Phosphoenolpyruvate carboxylase_subgroup; TIGRFAM: Phosphoenolpyruvate carboxylase_subgroup; HAMAP: Phosphoenolpyruvate carboxylase_subgroup; KEGG: dau:Daud_0773 phosphoenolpyruvate carboxylase. (493 aa)
AEH23676.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; KEGG: dbr:Deba_3204 pyruvate/ketoisovalerate oxidoreductase, subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase. (185 aa)
AEH23677.1KEGG: sfu:Sfum_2793 pyruvate ferredoxin/flavodoxin oxidoreductase subunit delta; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup. (97 aa)
AEH23678.1KEGG: dbr:Deba_3202 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (389 aa)
AEH23679.1Pyruvate synthase; KEGG: sfu:Sfum_2795 thiamine pyrophosphate binding domain-containing protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (317 aa)
AEH23691.1TIGRFAM: Homoserine kinase, putative; Cofactor-independent phosphoglycerate mutase, archaeal; KEGG: tye:THEYE_A1682 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme. (435 aa)
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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