(14 nodes) Preribosome, large subunit precursor, and Ribosomal protein L1-like network (Danio rerio)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	mrto4	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (242 aa)
	wdr12	Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (422 aa)
	pes	Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (583 aa)
	ddx18	RNA helicase. (653 aa)
	nifk	MKI67 FHA domain-interacting nucleolar phosphoprotein; Plays an essential role in early embryonic development. (269 aa)
	rsl1d1	Ribosomal L1 domain-containing 1. (373 aa)
	nip7	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. (180 aa)
	wdr74	WD repeat domain 74. (375 aa)
	mak16	Protein MAK16 homolog; Plays an essential role in early embryonic development. (305 aa)
	rpf1	Ribosome production factor 1; May be required for ribosome biogenesis. (352 aa)
	bop1	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (785 aa)
	bxdc2	Brix domain-containing 2. (383 aa)
	rrp1	Ribosomal RNA-processing 1. (673 aa)
	ebna1bp2	EBNA1-binding protein 2. (308 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
bop1	bxdc2	ENSDARP00000120969	ENSDARP00000130248	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing 2.	0.990
bop1	ddx18	ENSDARP00000120969	ENSDARP00000048752	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.987
bop1	ebna1bp2	ENSDARP00000120969	ENSDARP00000151663	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	EBNA1-binding protein 2.	0.987
bop1	mak16	ENSDARP00000120969	ENSDARP00000098580	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16 homolog; Plays an essential role in early embryonic development.	0.968
bop1	mrto4	ENSDARP00000120969	ENSDARP00000002982	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.990
bop1	nifk	ENSDARP00000120969	ENSDARP00000059548	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	MKI67 FHA domain-interacting nucleolar phosphoprotein; Plays an essential role in early embryonic development.	0.979
bop1	nip7	ENSDARP00000120969	ENSDARP00000076524	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.	0.981
bop1	pes	ENSDARP00000120969	ENSDARP00000026992	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
bop1	rpf1	ENSDARP00000120969	ENSDARP00000117162	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome production factor 1; May be required for ribosome biogenesis.	0.978
bop1	rrp1	ENSDARP00000120969	ENSDARP00000139145	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal RNA-processing 1.	0.993
bop1	rsl1d1	ENSDARP00000120969	ENSDARP00000072728	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal L1 domain-containing 1.	0.991
bop1	wdr12	ENSDARP00000120969	ENSDARP00000004327	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
bop1	wdr74	ENSDARP00000120969	ENSDARP00000083528	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD repeat domain 74.	0.993
bxdc2	bop1	ENSDARP00000130248	ENSDARP00000120969	Brix domain-containing 2.	Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.990
bxdc2	ddx18	ENSDARP00000130248	ENSDARP00000048752	Brix domain-containing 2.	RNA helicase.	0.991
bxdc2	ebna1bp2	ENSDARP00000130248	ENSDARP00000151663	Brix domain-containing 2.	EBNA1-binding protein 2.	0.999
bxdc2	mak16	ENSDARP00000130248	ENSDARP00000098580	Brix domain-containing 2.	Protein MAK16 homolog; Plays an essential role in early embryonic development.	0.984
bxdc2	mrto4	ENSDARP00000130248	ENSDARP00000002982	Brix domain-containing 2.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.990
bxdc2	nifk	ENSDARP00000130248	ENSDARP00000059548	Brix domain-containing 2.	MKI67 FHA domain-interacting nucleolar phosphoprotein; Plays an essential role in early embryonic development.	0.998
bxdc2	nip7	ENSDARP00000130248	ENSDARP00000076524	Brix domain-containing 2.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.	0.995

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