STRINGSTRING
sec23b sec23b pef1 pef1 sec24d sec24d sar1ab sar1ab kdelr3 kdelr3 mia3 mia3 sec24b sec24b serpinh1a serpinh1a sec31a sec31a si:dkey-9k7.3 si:dkey-9k7.3 A2BGJ8_DANRE A2BGJ8_DANRE F1R2Z4_DANRE F1R2Z4_DANRE sec31b sec31b sec24a sec24a klhl12 klhl12 sec24c sec24c sec16b sec16b sar1b sar1b sec23a sec23a preb preb ctage5 ctage5 KLHL12 KLHL12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sec23bProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (766 aa)
pef1Peflin; Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. Acts as a negative regulator of ER-Golgi transport (By similarity). (270 aa)
sec24dSEC24 homolog D, COPII coat complex component. (1030 aa)
sar1abSecretion-associated, Ras-related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
kdelr3ER lumen protein-retaining receptor 3; Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. (215 aa)
mia3MIA SH3 domain ER export factor 3. (1874 aa)
sec24bSEC24 homolog B, COPII coat complex component. (1184 aa)
serpinh1aSerpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (403 aa)
sec31aProtein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1250 aa)
si:dkey-9k7.3Si:dkey-9k7.3. (648 aa)
A2BGJ8_DANRESi:dkey-13n15.2. (128 aa)
F1R2Z4_DANRESi:dkey-13n15.2. (326 aa)
sec31bSEC31 homolog B, COPII coat complex component. (1171 aa)
sec24aSEC24 homolog A, COPII coat complex component. (1096 aa)
klhl12Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division (By similarity). Negatively regulates the Wnt signaling pathway, possibly via the targeted ubiquitination and subsequent proteolysis of dvl2 and dvl3. Regulates convergent-extension movements during early [...] (314 aa)
sec24cSEC24 homolog C, COPII coat complex component. (1248 aa)
sec16bSEC16 homolog B, endoplasmic reticulum export factor. (935 aa)
sar1bSecretion-associated, Ras-related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
sec23aProtein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
prebProlactin regulatory element-binding. (425 aa)
ctage5MIA SH3 domain ER export factor 2. (691 aa)
KLHL12Kelch like family member 12. (255 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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