STRINGSTRING
F1R4C2_DANRE F1R4C2_DANRE napsa napsa m6pr m6pr rab4b rab4b ctsl.1 ctsl.1 ctss2.2 ctss2.2 ctss1 ctss1 cln3 cln3 psap psap ppt1 ppt1 ctsh ctsh igf2r igf2r cts12 cts12 ctsz ctsz pglyrp5 pglyrp5 nsmaf nsmaf ctso ctso ctsba ctsba serpinb1 serpinb1 E7F3A5_DANRE E7F3A5_DANRE F1QQY3_DANRE F1QQY3_DANRE ctsd ctsd colec12 colec12 eea1 eea1 zgc:163030 zgc:163030 zgc:158254 zgc:158254 LOC108191752 LOC108191752 grnb grnb si:dkey-26g8.5 si:dkey-26g8.5 org org cln5 cln5 zgc:174855 zgc:174855 ctss2.1 ctss2.1 brinp1 brinp1 sorcs3b sorcs3b zgc:174154 zgc:174154 lamp2 lamp2 ggh ggh LOC100005175 LOC100005175 gm2a gm2a ctsla ctsla E7F8Y7_DANRE E7F8Y7_DANRE grna grna ctsll ctsll sort1b sort1b ctslb ctslb lamp1b lamp1b E9QBE2_DANRE E9QBE2_DANRE cln8 cln8 tpp1 tpp1 E9QE79_DANRE E9QE79_DANRE zgc:174153 zgc:174153 gga3a gga3a sort1a sort1a pxdn pxdn ctsf ctsf LOC553228 LOC553228 ADAMTS7 ADAMTS7 tmprss2 tmprss2 ctsc ctsc gga3b gga3b tpmt.2 tpmt.2 zgc:171566 zgc:171566 LOC100333521 LOC100333521 mfsd8 mfsd8 ctsbb ctsbb cln6a cln6a LOC108179180 LOC108179180 GM2A GM2A LOC569153 LOC569153 ENSDARP00000146241 ENSDARP00000146241 LOC100005129 LOC100005129 MGC174155 MGC174155 lgmn lgmn gga1 gga1 slc19a1 slc19a1 cst14b.2 cst14b.2 LOC100005356 LOC100005356 cln6b cln6b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F1R4C2_DANRESi:busm1-57f23.1. (144 aa)
napsaNapsin A aspartic peptidase; Belongs to the peptidase A1 family. (412 aa)
m6prMannose-6-phosphate receptor (cation-dependent). (265 aa)
rab4bRas-related protein Rab-4B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (213 aa)
ctsl.1Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
ctss2.2Cathepsin S, ortholog 2, tandem duplicate 2; Belongs to the peptidase C1 family. (330 aa)
ctss1Cathepsin S, ortholog 1; Belongs to the peptidase C1 family. (328 aa)
cln3Battenin. (446 aa)
psapProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (520 aa)
ppt1Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (330 aa)
igf2rCation-independent mannose 6-phosphate receptor. (2459 aa)
cts12Cathepsin 12; Belongs to the peptidase C1 family. (349 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (301 aa)
pglyrp5Peptidoglycan recognition protein 5. (238 aa)
nsmafNeutral sphingomyelinase (N-SMase) activation-associated factor. (911 aa)
ctsoCathepsin O; Belongs to the peptidase C1 family. (334 aa)
ctsbaCathepsin B, a; Belongs to the peptidase C1 family. (330 aa)
serpinb1Serpin peptidase inhibitor, clade B (Ovalbumin), member 1; Belongs to the serpin family. (380 aa)
E7F3A5_DANRESi:ch211-212k18.7. (300 aa)
F1QQY3_DANRESortilin. (423 aa)
ctsdCtsd protein; Belongs to the peptidase A1 family. (398 aa)
colec12Collectin-12; Scavenger receptor that displays several functions associated with host defense. Binds to carbohydrates (By similarity). (720 aa)
eea1Early endosome antigen 1. (1398 aa)
zgc:163030Zgc:163030; Belongs to the cystatin family. (128 aa)
zgc:158254Zgc:158254. (478 aa)
LOC108191752Uncharacterized protein. (263 aa)
grnbGranulin b. (729 aa)
si:dkey-26g8.5MGC174857 protein; Belongs to the peptidase C1 family. (335 aa)
orgOogenesis-related protein. (215 aa)
cln5Uncharacterized protein. (329 aa)
zgc:174855Im:6910535 protein; Belongs to the peptidase C1 family. (335 aa)
ctss2.1Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (330 aa)
brinp1Bone morphogenetic protein/retinoic acid-inducible neural-specific 1. (759 aa)
sorcs3bSortilin-related VPS10 domain-containing receptor 3b. (1196 aa)
zgc:174154Im:6910535; Belongs to the peptidase C1 family. (335 aa)
lamp2Lysosomal-associated membrane protein 2. (355 aa)
gghFolate gamma-glutamyl hydrolase. (312 aa)
LOC100005175Legumain-like. (263 aa)
gm2aGM2 ganglioside activator. (200 aa)
ctslaCathepsin La; Belongs to the peptidase C1 family. (337 aa)
E7F8Y7_DANRESi:dkey-239j18.3; Belongs to the peptidase C1 family. (336 aa)
grnaGranulin a. (1049 aa)
ctsllCathepsin L,-like; Belongs to the peptidase C1 family. (337 aa)
sort1bSortilin. (828 aa)
ctslbCathepsin Lb; Belongs to the peptidase C1 family. (352 aa)
lamp1bLysosomal-associated membrane protein 1b. (253 aa)
E9QBE2_DANRESi:dkey-239j18.2; Belongs to the peptidase C1 family. (335 aa)
cln8CLN8 transmembrane ER and ERGIC protein. (289 aa)
tpp1Tripeptidyl-peptidase 1; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases (By similarity). Requires substrates with an unsubstituted N-terminus (By similarity). (582 aa)
E9QE79_DANRESi:dkey-269i1.4; Belongs to the peptidase C1 family. (336 aa)
zgc:174153Zgc:174153; Belongs to the peptidase C1 family. (336 aa)
gga3aGolgi-associated, gamma adaptin ear-containing, ARF-binding protein 3a. (702 aa)
sort1aSortilin; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Belongs to the VPS10-related sortilin family. SORT1 subfamily. (815 aa)
pxdnPeroxidasin. (1460 aa)
ctsfCathepsin F; Belongs to the peptidase C1 family. (473 aa)
LOC553228Folate gamma-glutamyl hydrolase. (317 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1660 aa)
tmprss2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (487 aa)
ctscCathepsin C; Belongs to the peptidase C1 family. (455 aa)
gga3bGolgi-associated, gamma adaptin ear-containing, ARF-binding protein 3b. (709 aa)
tpmt.2Thiopurine S-methyltransferase, tandem duplicate 2. (232 aa)
zgc:171566Folate gamma-glutamyl hydrolase. (314 aa)
LOC100333521Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
mfsd8Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily. (504 aa)
ctsbbCathepsin Bb; Belongs to the peptidase C1 family. (327 aa)
cln6aCLN6 transmembrane ER protein a. (298 aa)
LOC108179180Uncharacterized protein. (818 aa)
GM2AML domain-containing protein. (213 aa)
LOC569153Uncharacterized protein. (263 aa)
ENSDARP00000146241PKD domain-containing protein. (457 aa)
LOC100005129Uncharacterized protein. (263 aa)
MGC174155Cathepsin Lb; Belongs to the peptidase C1 family. (336 aa)
lgmnLegumain. (438 aa)
gga1Golgi-associated, gamma adaptin ear-containing, ARF-binding protein 1. (635 aa)
slc19a1Solute carrier family 19 member 1. (528 aa)
cst14b.2Cystatin 14b, tandem duplicate 2. (103 aa)
LOC100005356Uncharacterized protein. (263 aa)
cln6bCLN6 transmembrane ER protein b. (310 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.