node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC103910107 | hsp90aa1.1 | ENSDARP00000133511 | ENSDARP00000022302 | NACHT domain-containing protein. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.904 |
LOC103910107 | hsp90aa1.2 | ENSDARP00000133511 | ENSDARP00000026065 | NACHT domain-containing protein. | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | 0.904 |
LOC103910107 | hsp90ab1 | ENSDARP00000133511 | ENSDARP00000014978 | NACHT domain-containing protein. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.904 |
LOC103910107 | sugt1 | ENSDARP00000133511 | ENSDARP00000135565 | NACHT domain-containing protein. | SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. | 0.905 |
ahsa1a | cdc37 | ENSDARP00000115845 | ENSDARP00000131796 | AHA1, activator of heat shock protein ATPase homolog 1a. | Cell division cycle 37 homolog (S. cerevisiae). | 0.647 |
ahsa1a | fkbp4 | ENSDARP00000115845 | ENSDARP00000124772 | AHA1, activator of heat shock protein ATPase homolog 1a. | Peptidylprolyl isomerase. | 0.514 |
ahsa1a | fkbp5 | ENSDARP00000115845 | ENSDARP00000038578 | AHA1, activator of heat shock protein ATPase homolog 1a. | Peptidylprolyl isomerase. | 0.635 |
ahsa1a | hsp70.1 | ENSDARP00000115845 | ENSDARP00000109199 | AHA1, activator of heat shock protein ATPase homolog 1a. | Heat shock cognate 70-kd protein, tandem duplicate 1; Belongs to the heat shock protein 70 family. | 0.529 |
ahsa1a | hsp90aa1.1 | ENSDARP00000115845 | ENSDARP00000022302 | AHA1, activator of heat shock protein ATPase homolog 1a. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.879 |
ahsa1a | hsp90aa1.2 | ENSDARP00000115845 | ENSDARP00000026065 | AHA1, activator of heat shock protein ATPase homolog 1a. | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | 0.848 |
ahsa1a | hsp90ab1 | ENSDARP00000115845 | ENSDARP00000014978 | AHA1, activator of heat shock protein ATPase homolog 1a. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.782 |
ahsa1a | ppid | ENSDARP00000115845 | ENSDARP00000107677 | AHA1, activator of heat shock protein ATPase homolog 1a. | Peptidylprolyl isomerase D (Cyclophilin D). | 0.840 |
ahsa1a | ptges3a | ENSDARP00000115845 | ENSDARP00000054236 | AHA1, activator of heat shock protein ATPase homolog 1a. | Prostaglandin E synthase 3a (cytosolic). | 0.866 |
ahsa1a | stip1 | ENSDARP00000115845 | ENSDARP00000100503 | AHA1, activator of heat shock protein ATPase homolog 1a. | Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein). | 0.928 |
ahsa1a | sugt1 | ENSDARP00000115845 | ENSDARP00000135565 | AHA1, activator of heat shock protein ATPase homolog 1a. | SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. | 0.505 |
ar | fkbp4 | ENSDARP00000088795 | ENSDARP00000124772 | Androgen receptor. | Peptidylprolyl isomerase. | 0.900 |
ar | fkbp5 | ENSDARP00000088795 | ENSDARP00000038578 | Androgen receptor. | Peptidylprolyl isomerase. | 0.512 |
ar | hsp70.1 | ENSDARP00000088795 | ENSDARP00000109199 | Androgen receptor. | Heat shock cognate 70-kd protein, tandem duplicate 1; Belongs to the heat shock protein 70 family. | 0.485 |
ar | hsp90aa1.1 | ENSDARP00000088795 | ENSDARP00000022302 | Androgen receptor. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.782 |
ar | hsp90aa1.2 | ENSDARP00000088795 | ENSDARP00000026065 | Androgen receptor. | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | 0.801 |