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mmgt1 mmgt1 emc2 emc2 UBL4A UBL4A sgtb sgtb emc8 emc8 get3 get3 emc7 emc7 sgta sgta get4 get4 emc9 emc9 zgc:86609 zgc:86609 emc6 emc6 emc10 emc10 tmem208 tmem208 emc1 emc1 get1 get1 swi5 swi5 bag6 bag6 emc3 emc3 camlg camlg emc4-2 emc4-2 zgc:195050 zgc:195050 emc4 emc4 bag6l bag6l
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mmgt1Membrane magnesium transporter 1; Mediates Mg(2+) transport. (130 aa)
emc2ER membrane protein complex subunit 2; Belongs to the EMC2 family. (297 aa)
UBL4AUbiquitin-like protein 4A; As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches- containing proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins [...] (157 aa)
sgtbSmall glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. (320 aa)
emc8ER membrane protein complex subunit 8. (202 aa)
get3ATPase asna1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (341 aa)
emc7ER membrane protein complex subunit 7; Belongs to the EMC7 family. (237 aa)
sgtaSmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. (320 aa)
get4Guided entry of tail-anchored proteins factor 4. (322 aa)
emc9ER membrane protein complex subunit 9. (205 aa)
zgc:86609ER membrane protein complex subunit 3; Belongs to the EMC3 family. (253 aa)
emc6ER membrane protein complex subunit 6; Belongs to the EMC6 family. (110 aa)
emc10ER membrane protein complex subunit 10; Belongs to the EMC10 family. (257 aa)
tmem208Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy; Belongs to the TMEM208 family. (175 aa)
emc1ER membrane protein complex subunit 1. (964 aa)
get1Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail-anchored (TA) proteins into the ER membrane. (170 aa)
swi5SWI5 homologous recombination repair protein. (141 aa)
bag6BCL2-associated athanogene 6. (1209 aa)
emc3ER membrane protein complex subunit 3. (261 aa)
camlgCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (253 aa)
emc4-2ER membrane protein complex subunit 4; May mediate anti-apoptotic activity. (66 aa)
zgc:195050Zgc:195050. (187 aa)
emc4ER membrane protein complex subunit 4. (65 aa)
bag6lLarge proline-rich protein BAG6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the bag6/bat3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1216 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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