STRINGSTRING
wnt11f2 wnt11f2 prickle2a prickle2a dvl2 dvl2 daam1a daam1a daam1b daam1b vangl1 vangl1 vangl2 vangl2 tbx1 tbx1 celsr1a celsr1a prickle1a prickle1a celsr2 celsr2 fzd3a fzd3a dvl3a dvl3a ptk7a ptk7a wnt11 wnt11 ankrd6b ankrd6b prickle1b prickle1b prickle2b prickle2b fzd6 fzd6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
wnt11f2Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. (353 aa)
prickle2aPrickle homolog 2a. (869 aa)
dvl2Dishevelled segment polarity protein 2. (747 aa)
daam1aDishevelled-associated activator of morphogenesis 1a. (1084 aa)
daam1bDishevelled-associated activator of morphogenesis 1b. (1079 aa)
vangl1Vang-like protein. (527 aa)
vangl2Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...] (526 aa)
tbx1T-box transcription factor TBX1; May act as a transcriptional factor. Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily. (460 aa)
celsr1aCadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family. (3044 aa)
prickle1aPrickle homolog 1a. (793 aa)
celsr2Cadherin, EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2940 aa)
fzd3aTransmembrane receptor frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (685 aa)
dvl3aDishevelled segment polarity protein 3a. (676 aa)
ptk7aProtein tyrosine kinase 7a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1061 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ankrd6bAnkyrin repeat domain 6b. (728 aa)
prickle1bPrickle homolog 1b. (863 aa)
prickle2bPrickle homolog 2b. (840 aa)
fzd6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (617 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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