STRINGSTRING
sart1 sart1 sf3a2 sf3a2 ddx23 ddx23 snrpc snrpc snrpd3 snrpd3 snrpb snrpb snrpd1 snrpd1 snrpa snrpa eftud2 eftud2 snrnp40 snrnp40 snrpe snrpe snrnp70 snrnp70 snrpb2 snrpb2 snrpd2 snrpd2 prpf4 prpf4 snrnp200 snrnp200 snrpd3l snrpd3l prpf3 prpf3 snrpa1 snrpa1 prpf31 prpf31 txnl4a txnl4a prpf8 prpf8 snrpg snrpg snrpf snrpf ddx46 ddx46 sf3a3 sf3a3 prpf6 prpf6 sf3a1 sf3a1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sart1Spliceosome-associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (777 aa)
sf3a2Splicing factor 3a, subunit 2. (278 aa)
ddx23DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (807 aa)
snrpcU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
snrpd3Small nuclear ribonucleoprotein Sm D3. (127 aa)
snrpbSmall nuclear ribonucleoprotein-associated protein. (239 aa)
snrpd1Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
snrpaSmall nuclear ribonucleoprotein polypeptide A. (281 aa)
eftud2Elongation factor Tu GTP-binding domain-containing 2. (973 aa)
snrnp40Small nuclear ribonucleoprotein 40 (U5). (347 aa)
snrpeSmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa)
snrnp70Small nuclear ribonucleoprotein 70 (U1). (495 aa)
snrpb2Small nuclear ribonucleoprotein polypeptide B2. (220 aa)
snrpd2Small nuclear ribonucleoprotein Sm D2. (118 aa)
prpf4PRP4 pre-mRNA-processing factor 4 homolog (yeast). (507 aa)
snrnp200Small nuclear ribonucleoprotein 200 (U5). (2134 aa)
snrpd3lSmall nuclear ribonucleoprotein Sm D3. (128 aa)
prpf3PRP3 pre-mRNA-processing factor 3 homolog (yeast). (699 aa)
snrpa1Small nuclear ribonucleoprotein polypeptide A. (277 aa)
prpf31U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. (508 aa)
txnl4aThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
prpf8Pre-mRNA-processing factor 8. (2342 aa)
snrpgSmall nuclear ribonucleoprotein G. (76 aa)
snrpfSmall nuclear ribonucleoprotein polypeptide F. (88 aa)
ddx46Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation; Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1018 aa)
sf3a3Splicing factor 3a, subunit 3. (501 aa)
prpf6PRP6 pre-mRNA-processing factor 6 homolog (S. cerevisiae). (974 aa)
sf3a1Novel protein similar to human splicing factor 3a, subunit 1, 120kD (SF3A1). (780 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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