node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSDARP00000137311 | cdh5 | ENSDARP00000137311 | ENSDARP00000104309 | Si:dkey-237i9.8. | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | 0.705 |
ENSDARP00000137311 | pecam1 | ENSDARP00000137311 | ENSDARP00000079164 | Si:dkey-237i9.8. | Platelet/endothelial cell adhesion molecule 1. | 0.909 |
ENSDARP00000137311 | ptpn6 | ENSDARP00000137311 | ENSDARP00000148161 | Si:dkey-237i9.8. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.950 |
adamts3 | ccbe1 | ENSDARP00000078846 | ENSDARP00000106577 | ADAM metallopeptidase with thrombospondin type 1 motif, 3. | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | 0.952 |
adamts3 | flt4 | ENSDARP00000078846 | ENSDARP00000133227 | ADAM metallopeptidase with thrombospondin type 1 motif, 3. | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | 0.667 |
adamts3 | prox1a | ENSDARP00000078846 | ENSDARP00000071943 | ADAM metallopeptidase with thrombospondin type 1 motif, 3. | Prospero homeobox 1a. | 0.445 |
adamts3 | sox18 | ENSDARP00000078846 | ENSDARP00000113837 | ADAM metallopeptidase with thrombospondin type 1 motif, 3. | SRY-box transcription factor 18. | 0.580 |
adamts3 | vegfd | ENSDARP00000078846 | ENSDARP00000121602 | ADAM metallopeptidase with thrombospondin type 1 motif, 3. | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. | 0.745 |
ccbe1 | adamts3 | ENSDARP00000106577 | ENSDARP00000078846 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | ADAM metallopeptidase with thrombospondin type 1 motif, 3. | 0.952 |
ccbe1 | flt4 | ENSDARP00000106577 | ENSDARP00000133227 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | 0.868 |
ccbe1 | lyve1b | ENSDARP00000106577 | ENSDARP00000155383 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | Lymphatic vessel endothelial hyaluronic receptor 1b. | 0.833 |
ccbe1 | mrc1a | ENSDARP00000106577 | ENSDARP00000137226 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | Mannose receptor, C type 1a. | 0.478 |
ccbe1 | nr2f2 | ENSDARP00000106577 | ENSDARP00000107285 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | Drosophila seven-up homolog/mammalian ARP-1 homolog. | 0.589 |
ccbe1 | prox1a | ENSDARP00000106577 | ENSDARP00000071943 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | Prospero homeobox 1a. | 0.745 |
ccbe1 | sox18 | ENSDARP00000106577 | ENSDARP00000113837 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | SRY-box transcription factor 18. | 0.837 |
ccbe1 | vegfd | ENSDARP00000106577 | ENSDARP00000121602 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. | 0.851 |
cdh5 | ENSDARP00000137311 | ENSDARP00000104309 | ENSDARP00000137311 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Si:dkey-237i9.8. | 0.705 |
cdh5 | flt4 | ENSDARP00000104309 | ENSDARP00000133227 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. | 0.893 |
cdh5 | lyve1b | ENSDARP00000104309 | ENSDARP00000155383 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Lymphatic vessel endothelial hyaluronic receptor 1b. | 0.618 |
cdh5 | nr2f2 | ENSDARP00000104309 | ENSDARP00000107285 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Drosophila seven-up homolog/mammalian ARP-1 homolog. | 0.462 |