STRINGSTRING
neflb neflb mdkb mdkb mycn mycn mdka mdka ltk ltk hmga2 hmga2 igf2bp1 igf2bp1 zeb2b zeb2b her4.3 her4.3 alkal1 alkal1 dusp12 dusp12 lin28b lin28b col28a1a col28a1a alkal2a alkal2a ddx4 ddx4 lmo7b lmo7b elavl4 elavl4 ros1 ros1 ptpn3 ptpn3 alk alk hace1 hace1 ptprz1a ptprz1a prph prph alkal2b alkal2b col28a1b col28a1b phox2bb phox2bb ptn ptn ptprz1b ptprz1b EML4 EML4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
neflbNeurofilament, light polypeptide b; Belongs to the intermediate filament family. (579 aa)
mdkbMidkine-related growth factor Mdk2. (147 aa)
mycnN-myc protein; May function as a transcription factor. (503 aa)
mdkaMidkine-related growth factor Mdk1. (146 aa)
ltkTyrosine-protein kinase receptor. (1530 aa)
hmga2High mobility group AT-hook 2. (110 aa)
igf2bp1Insulin-like growth factor 2 mRNA-binding protein 1; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons (By similarity). Regulates localized beta- actin/AC [...] (598 aa)
zeb2bZinc finger E-box-binding homeobox 2b. (1219 aa)
her4.3Hairy-related 4, tandem duplicate 3. (152 aa)
alkal1ALK and LTK ligand 1. (170 aa)
dusp12Dual-specificity phosphatase 12. (305 aa)
lin28bLin-28 homolog B (C. elegans). (210 aa)
col28a1aCollagen, type XXVIII, alpha 1a. (1170 aa)
alkal2aALK and LTK ligand 2a. (169 aa)
ddx4DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family. (716 aa)
lmo7bLIM domain 7b. (1384 aa)
elavl4ELAV-like protein 4; RNA-binding protein that is involved in the post- transcriptional regulation of mRNAs (By similarity). Plays a role in the regulation of mRNA stability, alternative splicing and translation (By similarity). Binds to AU-rich element (ARE) sequences in the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Mainly plays a role in neuron-specific RNA processing (By similarity). Required for the maturation of motor neuron axonal branches and dendrites. (408 aa)
ros1Tyrosine-protein kinase receptor. (1289 aa)
ptpn3Protein tyrosine phosphatase non-receptor type 3. (839 aa)
alkTyrosine-protein kinase receptor. (1181 aa)
hace1E3 ubiquitin-protein ligase HACE1; E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. (905 aa)
ptprz1aProtein tyrosine phosphatase receptor type Z1a. (1837 aa)
prphPrph protein; Belongs to the intermediate filament family. (442 aa)
alkal2bALK and LTK ligand 2b. (195 aa)
col28a1bCollagen, type XXVIII, alpha 1b. (1109 aa)
phox2bbPaired-like homeobox 2Bb. (284 aa)
ptnPleiotrophin. (158 aa)
ptprz1bProtein tyrosine phosphatase receptor type Z1b. (1303 aa)
EML4EMAP like 4. (956 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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