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cgas | Cyclic GMP-AMP synthase. (592 aa) | ||||
traf3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa) | ||||
ikbke | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (721 aa) | ||||
irf3 | Interferon regulatory factor 3. (426 aa) | ||||
tbkbp1 | TBK1-binding protein 1. (632 aa) | ||||
tbk1 | TANK-binding kinase 1. (727 aa) | ||||
tank | TRAF family member-associated NFKB activator. (348 aa) | ||||
irf5 | Interferon regulatory factor 5. (516 aa) | ||||
sting1 | Stimulator of interferon genes protein; Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Acts by binding cyclic dinucleotides: recognizes and binds cyclic di- GMP (c-di-GMP), a second messenger produced by bacteria, and cyclic GMP-AMP (cGAMP), a messenger produced by CGAS in response to DNA virus in the cytosol (By similarity). [...] (398 aa) | ||||
tlr9 | Toll-like receptor 9; Belongs to the Toll-like receptor family. (1069 aa) |