STRINGSTRING
mc1r mc1r mitfb mitfb slc24a5 slc24a5 slc45a2 slc45a2 gpr143 gpr143 tyrp1a tyrp1a tyrp1b tyrp1b asip1 asip1 pmela pmela dct dct tyr tyr frmd7 frmd7 oca2 oca2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mc1rMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (323 aa)
mitfbMicrophthalmia-associated transcription factor b. (500 aa)
slc24a5Sodium/potassium/calcium exchanger 5; Cation exchanger which plays a central role in pigmentation, possibly by participating in ion transport in melanosomes. Probably transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. (513 aa)
slc45a2Solute carrier family 45 member 2. (554 aa)
gpr143G protein-coupled receptor 143. (412 aa)
tyrp1aTyrosinase-related protein 1a. (524 aa)
tyrp1bTyrosinase-related protein 1b. (526 aa)
asip1Agouti-signaling protein 1. (125 aa)
pmelaPremelanosome protein a. (825 aa)
dctDopachrome tautomerase. (513 aa)
tyrTyrosinase. (535 aa)
frmd7FERM domain-containing 7. (636 aa)
oca2Oculocutaneous albinism II. (809 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.