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gid8a gid8a wdr26a wdr26a GID4 GID4 armc8 armc8 ranbp10 ranbp10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gid8aGlucose-induced degradation protein 8-A homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation (By similarity). Required for normal Wnt signaling and normal dorsoventral patterning during embryogenesis. Belongs to the GID8 family. (228 aa)
wdr26aWD repeat domain 26a. (463 aa)
GID4GID complex subunit 4 homolog. (217 aa)
armc8Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins. (674 aa)
ranbp10Ran-binding protein 10; May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. (609 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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