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arhgdia arhgdia cd2ap cd2ap trpc6a trpc6a nphs2 nphs2 kank2 kank2 arhgap24 arhgap24 nphs1 nphs1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
arhgdiaRho GDP dissociation inhibitor (GDI) alpha. (203 aa)
cd2apCD2-associated protein. (657 aa)
trpc6aTransient receptor potential cation channel, subfamily C, member 6a; Belongs to the transient receptor (TC 1.A.4) family. (874 aa)
nphs2NPHS2 stomatin family member, podocin. (406 aa)
kank2KN motif and ankyrin repeat domain-containing protein 2; May be involved in different biological processes including transcription and apoptosis by sequestering specific proteins outside of the nucleus (By similarity). Involved in actin stress fibers formation probably through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (By similarity). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney. (1085 aa)
arhgap24Rho GTPase-activating protein 24. (752 aa)
nphs1NPHS1 adhesion molecule, nephrin. (1287 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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