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| | fzr1a | Fizzy/cell division cycle 20 related 1 (Drosophila). (495 aa) |
| | cks1b | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | cdc25b | Cell division cycle 25B. (563 aa) |
| | mad2l1 | MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa) |
| | ccng2 | Cyclin G2; Belongs to the cyclin family. (330 aa) |
| | kif11 | Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1062 aa) |
| | bicral | BRD4-interacting chromatin-remodeling complex-associated protein-like. (824 aa) |
| | cdkn1ca | Cyclin-dependent kinase inhibitor 1C (P57, Kip2). (212 aa) |
| | cdc14aa | Cell division cycle 14Aa. (592 aa) |
| | zgc:56231 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (810 aa) |
| | ndc80 | Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores t [...] (632 aa) |
| | kif4 | Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1248 aa) |
| | pbk | Lymphokine-activated killer T-cell-originated protein kinase homolog. (339 aa) |
| | nusap1 | Nucleolar and spindle-associated protein 1; Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them (By similarity). (446 aa) |
| | nek2 | NIMA (Never in mitosis gene a)-related kinase 2. (440 aa) |
| | zw10 | Zw10 kinetochore protein. (771 aa) |
| | racgap1 | Rac GTPase-activating protein 1. (654 aa) |
| | ccna1 | Cyclin A1; Belongs to the cyclin family. (391 aa) |
| | rb1 | Retinoblastoma 1. (903 aa) |
| | kif18a | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (895 aa) |
| | zgc:153311 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | plk2b | Serine/threonine-protein kinase PLK. (657 aa) |
| | kif23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (867 aa) |
| | nsl1 | NSL1 component of MIS12 kinetochore complex. (238 aa) |
| | mis12 | MIS12 kinetochore complex component. (215 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | ccnd3 | Cyclin D3; Belongs to the cyclin family. (277 aa) |
| | pane1 | Centromere protein M; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. (186 aa) |
| | nuf2 | Kinetochore protein Nuf2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (454 aa) |
| | ncaph2 | Condensin-2 complex subunit H2; Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. (592 aa) |
| | ube2s | Ubiquitin-conjugating enzyme E2 S; Catalyzes the covalent attachment of ubiquitin to other proteins. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme ube2c/ubch10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. (221 aa) |
| | melk | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Also plays a role in primitive hematopoiesis, possibly by affecting the expression of genes critical for hematopoiesis; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. (676 aa) |
| | ncapd3 | Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1419 aa) |
| | cdk21 | Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (305 aa) |
| | mis18a | MIS18 kinetochore protein A. (192 aa) |
| | ENSDARP00000052802 | Si:dkey-30c15.10. (966 aa) |
| | aurkb | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] (320 aa) |
| | cenpl | Centromere protein L; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation; Belongs to the CENP-L/IML3 family. (351 aa) |
| | e2f5 | E2F transcription factor 5. (363 aa) |
| | cdkn3 | Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (208 aa) |
| | ska1 | Spindle and kinetochore-associated protein 1; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a [...] (258 aa) |
| | anapc4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (797 aa) |
| | spc24 | Kinetochore protein Spc24; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. (202 aa) |
| | ccnb1 | Cyclin B1; Belongs to the cyclin family. (397 aa) |
| | cenpn | Centromere protein N. (345 aa) |
| | cenpp | Centromere protein P; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation; Belongs to the CENP-P/CTF19 family. (282 aa) |
| | cdc23 | CDC23 (Cell division cycle 23, yeast, homolog). (579 aa) |
| | kif20a | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (921 aa) |
| | tpst1l | Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (349 aa) |
| | dlgap5 | Discs, large (Drosophila) homolog-associated protein 5. (909 aa) |
| | ccnd2a | Cyclin D2, a; Belongs to the cyclin family. (298 aa) |
| | rbl2 | Retinoblastoma-like 2 (p130). (1079 aa) |
| | rbl1 | Retinoblastoma-like 1 (p107). (1058 aa) |
| | cenpi | Centromere protein I. (732 aa) |
| | pttg1 | PTTG1 regulator of sister chromatid separation, securin. (182 aa) |
| | cdkn1bb | Cyclin-dependent kinase inhibitor 1b (P27, kip1). (179 aa) |
| | cntd2 | Cyclin N-terminal domain-containing 2; Belongs to the cyclin family. (398 aa) |
| | tfdp1a | Transcription factor. (409 aa) |
| | cdc16 | Cell division cycle 16 homolog (S. cerevisiae). (616 aa) |
| | zwilch | Protein zwilch homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mad1-mad2 complexes onto kinetochores (By similarity). (583 aa) |
| | plk1 | Serine/threonine-protein kinase PLK. (595 aa) |
| | ect2 | Epithelial cell-transforming 2. (976 aa) |
| | ccnj | Cyclin J; Belongs to the cyclin family. (351 aa) |
| | ncaph | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (690 aa) |
| | kif14 | Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1506 aa) |
| | anapc7 | Anaphase-promoting complex subunit 7. (566 aa) |
| | cdk4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (297 aa) |
| | ccny | Cyclin Y; Belongs to the cyclin family. (349 aa) |
| | A2CEF0_DANRE | Si:ch211-244o22.2. (807 aa) |
| | kif15 | Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1378 aa) |
| | cdk14 | Cyclin-dependent kinase 14; Belongs to the protein kinase superfamily. (324 aa) |
| | ccnd2b | Cyclin D2, b; Belongs to the cyclin family. (295 aa) |
| | cenps | Similar to apoptosis-inducing, TAF9-like domain 1. (127 aa) |
| | cks2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa) |
| | cdc14ab | Dual specificity protein phosphatase CDC14AB; Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. (510 aa) |
| | cdc25d | Cell division cycle 25 homolog d. (387 aa) |
| | cenpe | Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2690 aa) |
| | E7FFJ8_DANRE | Si:ch211-160f23.5. (438 aa) |
| | cdc26 | Anaphase-promoting complex subunit CDC26; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). May recruit the E2 ubiquitin-conjugating enzymes to the complex; Belongs to the CDC26 [...] (88 aa) |
| | fam89a | Family with sequence similarity 89 member A. (175 aa) |
| | bub1ba | BUB1 mitotic checkpoint serine/threonine kinase Ba. (722 aa) |
| | birc5a | Baculoviral IAP repeat-containing 5a. (190 aa) |
| | ccng1 | Cyclin G1; Belongs to the cyclin family. (299 aa) |
| | si:dkey-6i22.5 | Si:dkey-6i22.5. (219 aa) |
| | ncapd2 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1380 aa) |
| | smc2 | Structural maintenance of chromosomes protein. (1199 aa) |
| | spc25 | SPC25 component of NDC80 kinetochore complex. (234 aa) |
| | dsn1 | DSN1 component of MIS12 kinetochore complex. (330 aa) |
| | wee1 | Wee1-like protein kinase. (612 aa) |
| | ccni | Cyclin I; Belongs to the cyclin family. (355 aa) |
| | E7FCV0_DANRE | Si:dkey-185e18.7. (397 aa) |
| | E7F017_DANRE | Si:ch73-160p18.3. (2151 aa) |
| | E7F0Y9_DANRE | Si:ch211-91p5.3. (1162 aa) |
| | anapc16 | Anaphase-promoting complex subunit 16. (108 aa) |
| | kif17 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (823 aa) |
| | cita | Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2344 aa) |
| | smc4 | Structural maintenance of chromosomes protein. (1289 aa) |
| | cdk1 | Cell division control protein 2; Belongs to the protein kinase superfamily. (302 aa) |
| | cenpx | Centromere protein X. (81 aa) |
| | plk2a | Serine/threonine-protein kinase PLK. (670 aa) |
| | e2f3 | E2F transcription factor 3. (429 aa) |
| | E7FAC3_DANRE | Si:ch211-161h7.4. (1130 aa) |
| | cdc27 | Cell division cycle 27. (833 aa) |
| | cdkn1a | Cyclin-dependent kinase inhibitor 1A. (154 aa) |
| | prc1b | Protein regulator of cytokinesis 1b. (606 aa) |
| | cenpf | Centromere protein F. (2708 aa) |
| | ska3 | Spindle and kinetochore-associated protein 3; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. Affinity for microtubules is synergistically enhanced in the p [...] (495 aa) |
| | bub1 | BUB1 mitotic checkpoint serine/threonine kinase. (1202 aa) |
| | cdkn2c | Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (170 aa) |
| | B0UYN0_DANRE | Si:dkey-57a22.11. (847 aa) |
| | cdk16 | Cyclin-dependent kinase 16. (524 aa) |
| | knl1 | Kinetochore scaffold 1. (1794 aa) |
| | nupr1b | Nuclear protein 1b. (75 aa) |
| | zgc:86764 | Zgc:86764. (580 aa) |
| | zgc:153935 | Zgc:153935. (321 aa) |
| | cenpt | Si:ch211-225g23.1. (914 aa) |
| | ttk | Dual specificity protein kinase Ttk; Phosphorylates proteins on serine, threonine, and tyrosine (By similarity). Involved in mitotic cell cycle checkpoint control. Required for fin and heart regeneration. Required to prevent chromosome segregation errors during meiosis. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (983 aa) |
| | plk3 | Serine/threonine-protein kinase PLK. (660 aa) |
| | bicra | BRD4-interacting chromatin-remodeling complex-associated protein. (1771 aa) |
| | oip5 | Opa-interacting protein 5. (196 aa) |
| | mad1l1 | Mitotic arrest deficient-like protein 1. (717 aa) |
| | ncapg | Non-SMC condensin I complex, subunit G. (1003 aa) |
| | cenph | Centromere protein H. (233 aa) |
| | cenpk | Centromere protein K. (275 aa) |
| | anapc13 | Anaphase-promoting complex subunit 13. (74 aa) |
| | ncapg2 | Condensin-2 complex subunit G2; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis (By similarity). Plays a role in the embryonic development of the head and kidney structures. (1140 aa) |
| | cdc14b | Cell division cycle 14B. (476 aa) |
| | anapc10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | ttc41 | Tetratricopeptide repeat domain 41. (1112 aa) |
| | cdk6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (324 aa) |
| | bub3 | BUB3 mitotic checkpoint protein. (338 aa) |
| | kif20ba | Kinesin family member 20Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1683 aa) |
| | fzr1b | Fizzy/cell division cycle 20-related 1b. (485 aa) |
| | mis18bp1 | MIS18-binding protein 1. (1124 aa) |
| | espl1 | Extra spindle pole bodies-like 1, separase. (2182 aa) |
| | X1WFU2_DANRE | Si:ch73-147o17.1. (80 aa) |
| | X1WGM0_DANRE | Si:dkey-148h10.5. (152 aa) |
| | cenpo | Centromere protein O. (322 aa) |
| | anapc11 | APC11 anaphase-promoting complex subunit 11 homolog (yeast). (88 aa) |
| | anapc5 | Anaphase-promoting complex subunit 5. (718 aa) |
| | spdl1 | Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. May act as an adapter protein linking the dynein motor complex to various cargos (By similarity); Belongs to the Spindly family. (590 aa) |
| | e2f4 | E2F transcription factor 4. (404 aa) |
| | kntc1 | Kinetochore-associated 1. (2290 aa) |
| | chek1 | CHK1 checkpoint homolog (S. pombe); Belongs to the protein kinase superfamily. (410 aa) |
| | ENSDARP00000133573 | Si:ch73-106k19.2. (284 aa) |
| | klhdc4 | Kelch domain-containing 4. (585 aa) |
| | nudc | NudC nuclear distribution protein. (333 aa) |
| | cep55l | Centrosomal protein of 55 kDa; Plays a role in mitotic exit and cytokinesis. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis. Not required for microtubule nucleation (By similarity). Plays a role in the development of the brain and kidney. (435 aa) |
| | sgo1 | Shugoshin 1. (616 aa) |
| | Cenpw | Si:ch211-195p4.4. (127 aa) |
| | shcbp1 | SHC SH2-domain-binding protein 1. (721 aa) |
| | bod1l1 | Biorientation of chromosomes in cell division 1-like 1. (1651 aa) |
| | e2f1 | E2F transcription factor 1. (429 aa) |
| | kif22 | Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. (634 aa) |
| | CDK18 | Si:dkey-166c18.1; Belongs to the protein kinase superfamily. (465 aa) |
| | ENSDARP00000137794 | Si:dkeyp-115e12.6. (1694 aa) |
| | cenpw | Centromere protein W. (98 aa) |
| | stc2b | Stanniocalcin 2b. (313 aa) |
| | pclaf | PCNA clamp-associated factor. (102 aa) |
| | incenp | Uncharacterized protein. (815 aa) |
| | prc1a | Protein regulator of cytokinesis 1a. (598 aa) |
| | anapc2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (802 aa) |
| | ENSDARP00000140159 | Si:dkey-225f5.4. (378 aa) |
| | ccnd1 | G1/S-specific cyclin-D1; May play a role in transcriptional regulation (By similarity). Essential for the control of the cell cycle at the G1/S (start) transition. (291 aa) |
| | cdc20 | Cell division cycle 20 homolog. (496 aa) |
| | ccne2 | Cyclin E2; Belongs to the cyclin family. (392 aa) |
| | ccne1 | G1/S-specific cyclin-E1; Essential for the control of the cell cycle at the G1/S (start) transition; Belongs to the cyclin family. Cyclin E subfamily. (410 aa) |
| | ENSDARP00000142919 | Si:ch211-212k18.6. (1957 aa) |
| | anln | Anillin, actin-binding protein. (1171 aa) |
| | cdca8 | Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). (276 aa) |
| | zgc:86839 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (75 aa) |
| | bub1bb | BUB1 mitotic checkpoint serine/threonine kinase Bb. (456 aa) |
| | LOC100536316 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (482 aa) |
| | ntmt1 | N-terminal Xaa-Pro-Lys N-methyltransferase 1; Distributive alpha-N-methyltransferase that methylates the N- terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]- Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on target proteins. (243 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (454 aa) |
| | ube2c | Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (171 aa) |
| | ENSDARP00000147336 | Si:dkey-25o16.4. (1606 aa) |
| | anapc15 | Anaphase-promoting complex subunit 15. (173 aa) |
| | bod1 | Biorientation of chromosomes in cell division 1. (157 aa) |
| | anapc1 | Anaphase-promoting complex subunit 1. (1932 aa) |
| | ENSDARP00000150236 | Si:ch1073-416j23.1. (671 aa) |
| | cdkn2d | Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (168 aa) |
| | ENSDARP00000152227 | HORMA domain-containing protein. (61 aa) |
| | cdca3 | Si:ch211-69g19.2. (485 aa) |
| | cenpa | Histone H3-like centromeric protein A; Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required [...] (145 aa) |
| | ska2 | Spindle and kinetochore-associated protein 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a [...] (226 aa) |
| | casp17 | Uncharacterized protein; Belongs to the peptidase C14A family. (276 aa) |
| | tpx2 | TPX2 microtubule nucleation factor. (739 aa) |
