STRINGSTRING
actn3b actn3b kcnk1b kcnk1b mybpc1 mybpc1 kcnk13a kcnk13a myhb myhb clic2 clic2 abcc9 abcc9 mylz3 mylz3 tmod2 tmod2 kcnj2a kcnj2a casq2 casq2 fkbp1b fkbp1b tnni2b.1 tnni2b.1 atp1a2a atp1a2a kcnk6 kcnk6 tnni2a.3 tnni2a.3 tcap tcap ryr1b ryr1b itpr1b itpr1b camk2a camk2a myl7 myl7 myh11a myh11a atp2a1 atp2a1 camk2d2 camk2d2 mylka mylka tnnc1b tnnc1b cacnb1 cacnb1 nppb nppb atp1b3b atp1b3b kcnk3a kcnk3a kcnk1a kcnk1a cacng6b cacng6b kcnj11 kcnj11 mylpfa mylpfa kcnk2a kcnk2a atp2b1a atp2b1a ahcyl1 ahcyl1 gucy1b2 gucy1b2 kcnk7 kcnk7 itgb5 itgb5 zgc:86709 zgc:86709 atp1a1a.1 atp1a1a.1 sri sri desma desma pxnb pxnb trpc1 trpc1 atp1b2b atp1b2b viml viml kcnj4 kcnj4 nppc nppc myh7 myh7 slc8a3 slc8a3 gucy1a1 gucy1a1 camk2g1 camk2g1 cacng4b cacng4b KCNK12 KCNK12 tmod1 tmod1 myl9b myl9b lmod1b lmod1b gucy1b1 gucy1b1 vcla vcla myhz1.1 myhz1.1 myhc4 myhc4 KCNIP4 KCNIP4 myhz2 myhz2 nppa nppa slc8a1b slc8a1b myhz1.3 myhz1.3 E7FEN3_DANRE E7FEN3_DANRE tmod4 tmod4 sorbs3 sorbs3 itga1 itga1 myhz1.2 myhz1.2 atp1b1b atp1b1b myha myha cacna1c cacna1c E9QFE7_DANRE E9QFE7_DANRE npr1a npr1a neb neb tnni2b.2 tnni2b.2 myl12.2 myl12.2 cacng8a cacng8a camk2b1 camk2b1 kcnk15 kcnk15 stk38l stk38l kcnk10a kcnk10a kcnd1 kcnd1 ces3 ces3 tnnt3b tnnt3b GUCY1A2 GUCY1A2 cacng7a cacng7a kcnip2 kcnip2 tnni1b tnni1b tnni2a.2 tnni2a.2 tnnt2a tnnt2a X1WCD0_DANRE X1WCD0_DANRE X1WCE4_DANRE X1WCE4_DANRE itpr2 itpr2 Fxyd7 Fxyd7 atp2b2 atp2b2 corin corin tnni2a.1 tnni2a.1 ryr3 ryr3 npr2 npr2 kcnj12a kcnj12a kcnk4a kcnk4a mybpc2a mybpc2a tln1 tln1 pak1 pak1 slc8a2b slc8a2b cacnb2a cacnb2a fxyd6 fxyd6 itpr3 itpr3 myl2a myl2a casq1a casq1a myl10 myl10 Fxyd2 Fxyd2 prkacaa prkacaa nos1 nos1 sorbs1 sorbs1 pak2a pak2a myl12.1 myl12.1 LOC100329748 LOC100329748 camk2g2 camk2g2 kcnk9 kcnk9 atp1a3b atp1a3b kcnk17 kcnk17 kcnj14 kcnj14 mybpc3 mybpc3 acta2 acta2 aldh2.2 aldh2.2 tnnt1 tnnt1 fxyd1 fxyd1 unm_hu7910 unm_hu7910 myl4 myl4 atp2a3 atp2a3 kcnd2 kcnd2 tpm1 tpm1 RYR2 RYR2 KCNIP1 KCNIP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
actn3bActinin alpha 3b. (898 aa)
kcnk1bPotassium channel subfamily K member. (337 aa)
mybpc1Myosin-binding protein C1. (1167 aa)
kcnk13aPotassium channel, subfamily K, member 13a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (409 aa)
myhbMyosin, heavy chain b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
clic2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (239 aa)
abcc9ATP-binding cassette, sub-family C (CFTR/MRP), member 9. (1558 aa)
mylz3Fast skeletal muscle myosin light polypeptide 3. (151 aa)
tmod2Tropomodulin 2. (344 aa)
kcnj2aPotassium inwardly rectifying channel subfamily J member 2a. (427 aa)
casq2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (409 aa)
fkbp1bPeptidylprolyl isomerase. (108 aa)
tnni2b.1Troponin I type 2b (skeletal, fast), tandem duplicate 1. (176 aa)
atp1a2aSodium/potassium-transporting ATPase subunit alpha. (1017 aa)
kcnk6Potassium channel, subfamily K, member 6; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (324 aa)
tnni2a.3Troponin I type 2a (skeletal, fast), tandem duplicate 3. (176 aa)
tcapTitin-cap (telethonin). (179 aa)
ryr1bRyanodine receptor 1b (skeletal). (5078 aa)
itpr1bInositol 1,4,5-trisphosphate receptor, type 1b. (2782 aa)
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
myl7Myosin, light polypeptide 7, regulatory. (172 aa)
myh11aMyosin, heavy polypeptide 11, smooth muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
atp2a1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa)
camk2d2Calcium/calmodulin-dependent protein kinase type II delta 2 chain; CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system. (554 aa)
mylkaMyosin, light chain kinase a. (899 aa)
tnnc1bTroponin C type 1b (slow). (161 aa)
cacnb1Calcium channel, voltage-dependent, beta 1 subunit. (603 aa)
nppbNatriuretic peptide B. (129 aa)
atp1b3bSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (275 aa)
kcnk3aPotassium channel subfamily K member. (390 aa)
kcnk1aPotassium channel subfamily K member. (338 aa)
cacng6bCalcium channel, voltage-dependent, gamma subunit 6b. (264 aa)
kcnj11Potassium inwardly-rectifying channel, subfamily J, member 11. (381 aa)
mylpfaMyosin light chain, phosphorylatable, fast skeletal muscle a. (169 aa)
kcnk2aPotassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
atp2b1aCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1228 aa)
ahcyl1S-adenosylhomocysteine hydrolase-like 1; Belongs to the adenosylhomocysteinase family. (554 aa)
gucy1b2Guanylate cyclase 1, soluble, beta 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (757 aa)
kcnk7Potassium channel, subfamily K, member 7; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (342 aa)
itgb5Integrin beta; Belongs to the integrin beta chain family. (823 aa)
zgc:86709Novel actin protein. (377 aa)
atp1a1a.1Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
sriSorcin. (190 aa)
desmaDesmin a; Belongs to the intermediate filament family. (488 aa)
pxnbPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (525 aa)
trpc1Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (796 aa)
atp1b2bSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (292 aa)
vimlVimentin-like; Belongs to the intermediate filament family. (447 aa)
kcnj4Uncharacterized protein. (498 aa)
nppcNatriuretic peptide C. (131 aa)
myh7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
slc8a3Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (917 aa)
gucy1a1Soluble guanylate cyclase large subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (679 aa)
camk2g1Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1. (560 aa)
cacng4bVoltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (322 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (418 aa)
tmod1Tropomodulin 1. (356 aa)
myl9bMyosin, light polypeptide 9, regulatory. (173 aa)
lmod1bLeiomodin 1b (smooth muscle). (671 aa)
gucy1b1Soluble guanylate cyclase small subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (608 aa)
vclaVinculin a. (1131 aa)
myhz1.1Myosin, heavy polypeptide 1.1, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
myhc4Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (229 aa)
myhz2Myosin, heavy polypeptide 2, fast muscle-specific; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
nppaNatriuretic peptide A. (139 aa)
slc8a1bSolute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (944 aa)
myhz1.3Myosin, heavy polypeptide 1.3, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
E7FEN3_DANREFXYD domain-containing ion transport regulator; Belongs to the FXYD family. (166 aa)
tmod4Tropomodulin 4 (Muscle). (343 aa)
sorbs3Sorbin and SH3 domain-containing 3. (617 aa)
itga1Integrin, alpha 1; Belongs to the integrin alpha chain family. (1187 aa)
myhz1.2Myosin, heavy polypeptide 1.2, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
atp1b1bSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (317 aa)
myhaMyosin, heavy chain a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1933 aa)
cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2196 aa)
E9QFE7_DANRESi:rp71-17i16.4. (161 aa)
npr1aGuanylate cyclase. (1067 aa)
nebNebulin. (6177 aa)
tnni2b.2Troponin I type 2b (skeletal, fast), tandem duplicate 2. (176 aa)
myl12.2Myosin, light chain 12, genome duplicate 2. (172 aa)
cacng8aCalcium channel, voltage-dependent, gamma subunit 8a. (432 aa)
camk2b1Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1. (618 aa)
kcnk15Potassium channel subfamily K member. (357 aa)
stk38lNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (464 aa)
kcnk10aPotassium channel, subfamily K, member 10a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (569 aa)
kcnd1Potassium voltage-gated channel, Shal-related subfamily, member 1; Belongs to the potassium channel family. (632 aa)
ces3Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (549 aa)
tnnt3bTroponin T type 3b (skeletal, fast). (284 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (631 aa)
cacng7aVoltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (341 aa)
kcnip2Kv channel-interacting protein 2. (207 aa)
tnni1bTroponin I type 1b (skeletal, slow). (182 aa)
tnni2a.2Troponin I type 2a (skeletal, fast), tandem duplicate 2. (178 aa)
tnnt2aTroponin T type 2a (cardiac). (282 aa)
X1WCD0_DANRESi:ch211-266g18.10. (2046 aa)
X1WCE4_DANRESi:ch211-270g19.5. (52 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2008 aa)
Fxyd7FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (110 aa)
atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1253 aa)
corinCorin, serine peptidase. (833 aa)
tnni2a.1Troponin I type 2a (skeletal, fast), tandem duplicate 1. (178 aa)
ryr3Ryanodine receptor 3. (4987 aa)
npr2Guanylate cyclase. (1051 aa)
kcnj12aPotassium inwardly rectifying channel subfamily J member 12a. (437 aa)
kcnk4aPotassium channel, subfamily K, member 4a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (542 aa)
mybpc2aMyosin-binding protein Ca. (1131 aa)
tln1Talin 1. (2544 aa)
pak1Non-specific serine/threonine protein kinase. (587 aa)
slc8a2bSodium/calcium exchanger 2 isoform b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (961 aa)
cacnb2aCalcium channel, voltage-dependent, beta 2a. (636 aa)
fxyd6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (99 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2634 aa)
myl2aMyosin, light chain 2a, regulatory, cardiac, slow. (169 aa)
casq1aCalsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (553 aa)
myl10Myosin, light chain 10, regulatory. (167 aa)
Fxyd2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (59 aa)
prkacaaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (352 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1431 aa)
sorbs1Sorbin and SH3 domain-containing 1. (766 aa)
pak2aNon-specific serine/threonine protein kinase. (518 aa)
myl12.1Myosin, light chain 12, genome duplicate 1. (172 aa)
LOC100329748Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1390 aa)
camk2g2Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2. (637 aa)
kcnk9Potassium channel, subfamily K, member 9; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (490 aa)
atp1a3bSodium/potassium-transporting ATPase subunit alpha. (1023 aa)
kcnk17Potassium channel, subfamily K, member 17; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (299 aa)
kcnj14Potassium inwardly rectifying channel subfamily J member 14. (542 aa)
mybpc3Myosin-binding protein C3. (1287 aa)
acta2Actin, alpha 2, smooth muscle, aorta. (377 aa)
aldh2.2Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. (516 aa)
tnnt1Troponin T type 1 (skeletal, slow). (342 aa)
fxyd1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (98 aa)
unm_hu7910Un-named hu7910. (600 aa)
myl4Myosin, light chain 4, alkali; atrial, embryonic. (187 aa)
atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa)
kcnd2Potassium voltage-gated channel, Shal-related subfamily, member 2; Belongs to the potassium channel family. (630 aa)
tpm1Tropomyosin 1 (alpha); Belongs to the tropomyosin family. (284 aa)
RYR2Uncharacterized protein. (4478 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (232 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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