STRINGSTRING
atoh1a atoh1a gdf5 gdf5 lbx1b lbx1b foxg1b foxg1b ptch1 ptch1 atoh1c atoh1c gdf6a gdf6a gata2a gata2a nkx6.3 nkx6.3 foxg1a foxg1a foxg1d foxg1d tbx2b tbx2b foxg1c foxg1c gata2b gata2b ENSDARP00000125042 ENSDARP00000125042 atoh1b atoh1b thrb thrb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
atoh1aAtonal bHLH transcription factor 1a. (292 aa)
gdf5Growth differentiation factor 5. (474 aa)
lbx1bLadybird homeobox 1b. (265 aa)
foxg1bForkhead box G1b. (341 aa)
ptch1Protein patched homolog 1. (1475 aa)
atoh1cAtonal bHLH transcription factor 1c. (204 aa)
gdf6aGrowth/differentiation factor 6-A; Growth factor that controls proliferation and cellular differentiation in the retina. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Functions maternally in dorsal/ventral patterning to induce the expression of the zygotic bmp2b and bmp4 genes and ventralize embryos. Zygotic expression does not appear to regulate axis specification, but instead functions to establish the integrity of the axial vessels during embryon [...] (404 aa)
gata2aGATA-binding protein 2a. (456 aa)
nkx6.3NK6 homeobox 3. (272 aa)
foxg1aForkhead box G1a. (420 aa)
foxg1dForkhead box G1d. (316 aa)
tbx2bT-box transcription factor TBX2b; Involved in the transcriptional regulation of genes required for mesoderm differentiation. Plays a role in the specification of late notochordal precursor cells and formation of the differentiated notochord. Required for cardiac atrioventricular canal formation. (687 aa)
foxg1cForkhead box G1c. (379 aa)
gata2bGATA-binding protein 2b. (428 aa)
ENSDARP00000125042Patched 1. (120 aa)
atoh1bAtonal bHLH transcription factor 1b. (206 aa)
thrbThyroid hormone receptor beta; Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for the thyroid gland hormone triiodothyronine (T3). Transactivating activity is ligand-dependent, and is repressed in the absence of T3. (508 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]