STRINGSTRING
serpinf2a serpinf2a ENSDARP00000156326 ENSDARP00000156326 timp4.3 timp4.3 cst14b.2 cst14b.2 LOC101886910 LOC101886910 timp4.1 timp4.1 LOC110437957 LOC110437957 flot1a flot1a adgrg1-2 adgrg1-2 amfrb amfrb prkn prkn fadd fadd f3a f3a ecm1a ecm1a trip4 trip4 nfrkb nfrkb ecm1b ecm1b ripk2 ripk2 timp4.2 timp4.2 twnk twnk polg polg bcl2b bcl2b pdzd3a pdzd3a serpinf2b serpinf2b tysnd1 tysnd1 tnfaip3 tnfaip3 cflarb cflarb casp8ap2 casp8ap2 bcl2a bcl2a cltcb cltcb malt3 malt3 march6 march6 cd28 cd28 fn1a fn1a cltcl1 cltcl1 bcl2l10 bcl2l10 amfra amfra fbxo45 fbxo45 malt1 malt1 brca2 brca2 itga3b itga3b flot1b flot1b fn1b fn1b timp2b timp2b flot2b flot2b sftpbb sftpbb timp2a timp2a selenos selenos serpine1 serpine1 cflara cflara pdzd3b pdzd3b si:dkey-63b1.1 si:dkey-63b1.1 cltca cltca riok3 riok3 serpinc1 serpinc1 zgc:123321 zgc:123321 psap psap chmp3 chmp3 itga3a itga3a rnf139 rnf139 derl1 derl1 malt2 malt2 pink1 pink1 hdr hdr flot2a flot2a tnfb tnfb yipf5 yipf5 f3b f3b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
serpinf2aAlpha-2-antiplasmin; Belongs to the serpin family. (457 aa)
ENSDARP00000156326Uncharacterized protein. (94 aa)
timp4.3TIMP metallopeptidase inhibitor 4, tandem duplicate 3. (198 aa)
cst14b.2Cystatin 14b, tandem duplicate 2. (103 aa)
LOC101886910Cystatin domain-containing protein. (126 aa)
timp4.1TIMP metallopeptidase inhibitor 4, tandem duplicate 1. (229 aa)
LOC110437957CARD domain-containing protein. (201 aa)
flot1aFlotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (438 aa)
adgrg1-2Adhesion G protein-coupled receptor G1. (513 aa)
amfrbAutocrine motility factor receptor b. (459 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (458 aa)
faddFas (tnfrsf6)-associated via death domain. (192 aa)
f3aCoagulation factor IIIa. (294 aa)
ecm1aExtracellular matrix protein 1a. (173 aa)
trip4Thyroid hormone receptor interactor 4. (564 aa)
nfrkbNuclear factor-related to kappaB-binding protein. (1290 aa)
ecm1bExtracellular matrix protein 1b. (499 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (457 aa)
timp4.2TIMP metallopeptidase inhibitor 4, tandem duplicate 2. (201 aa)
twnkTwinkle mtDNA helicase. (728 aa)
polgPolymerase (DNA directed), gamma. (1206 aa)
bcl2bBCL2 apoptosis regulator b. (209 aa)
pdzd3aPDZ domain-containing 3a. (501 aa)
serpinf2bAlpha-2-antiplasmin; Belongs to the serpin family. (480 aa)
tysnd1Trypsin domain-containing 1. (521 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (756 aa)
cflarbCASP8 and FADD-like apoptosis regulator b. (178 aa)
casp8ap2Caspase 8-associated protein 2. (1995 aa)
bcl2aB-cell leukemia/lymphoma 2. (228 aa)
cltcbClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
malt3MALT paracaspase 3. (627 aa)
march6Membrane-associated ring finger (C3HC4) 6. (911 aa)
cd28CD28 molecule. (176 aa)
fn1aFibronectin 1a. (2480 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1638 aa)
bcl2l10BCL2-like 10 (Apoptosis facilitator). (176 aa)
amfraAutocrine motility factor receptor a. (620 aa)
fbxo45F-box/SPRY domain-containing protein 1; Belongs to the FBXO45/Fsn family. (291 aa)
malt1MALT paracaspase 1. (768 aa)
brca2BRCA2 DNA repair-associated. (2874 aa)
itga3bIntegrin, alpha 3b; Belongs to the integrin alpha chain family. (1041 aa)
flot1bFlotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (425 aa)
fn1bFibronectin 1b. (2500 aa)
timp2bTIMP metallopeptidase inhibitor 2b. (265 aa)
flot2bFlotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
sftpbbSurfactant protein Bb. (317 aa)
timp2aTissue inhibitor of metalloproteinase 2. (220 aa)
selenosSelenoprotein S; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner (By similarity). (190 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (392 aa)
cflaraCASP8 and FADD-like apoptosis regulator a; Belongs to the peptidase C14A family. (461 aa)
pdzd3bPDZ domain-containing 3b. (524 aa)
si:dkey-63b1.1Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
cltcaClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1680 aa)
riok3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (507 aa)
serpinc1Serine (Or cysteine) proteinase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family. (450 aa)
zgc:123321Zgc:123321. (247 aa)
psapProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (520 aa)
chmp3Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Involved in late stages of cytokinesis. Plays a role in en [...] (221 aa)
itga3aIntegrin, alpha 3a; Belongs to the integrin alpha chain family. (1053 aa)
rnf139Ring finger protein 139. (664 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (261 aa)
malt2MALT paracaspase 2. (806 aa)
pink1PTEN-induced kinase 1. (574 aa)
hdrHematopoietic death receptor. (418 aa)
flot2aFlotillin-2a; May play a role in axon growth and regeneration. May be involved in epidermal cell adhesion and epidermal structure and function (By similarity). (428 aa)
tnfbTumor necrosis factor b (TNF superfamily, member 2). (242 aa)
yipf5Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. (257 aa)
f3bCoagulation factor IIIb. (288 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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