node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSDARP00000155118 | dhh | ENSDARP00000155118 | ENSDARP00000053870 | Uncharacterized protein. | Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family. | 0.588 |
ENSDARP00000155118 | ihha | ENSDARP00000155118 | ENSDARP00000076101 | Uncharacterized protein. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.588 |
ENSDARP00000155118 | ihhb | ENSDARP00000155118 | ENSDARP00000076199 | Uncharacterized protein. | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. | 0.588 |
ENSDARP00000155118 | shha | ENSDARP00000155118 | ENSDARP00000125090 | Uncharacterized protein. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.588 |
ENSDARP00000155118 | shhb | ENSDARP00000155118 | ENSDARP00000056746 | Uncharacterized protein. | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. | 0.588 |
bbs1 | shha | ENSDARP00000104106 | ENSDARP00000125090 | Bardet-Biedl syndrome 1. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.506 |
bbs1 | shhb | ENSDARP00000104106 | ENSDARP00000056746 | Bardet-Biedl syndrome 1. | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. | 0.434 |
bbs1 | smo | ENSDARP00000104106 | ENSDARP00000013486 | Bardet-Biedl syndrome 1. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.918 |
boc | cdon | ENSDARP00000098383 | ENSDARP00000081773 | BOC cell adhesion-associated, oncogene-regulated. | Cell adhesion molecule-related/down-regulated by oncogenes. | 0.911 |
boc | dhh | ENSDARP00000098383 | ENSDARP00000053870 | BOC cell adhesion-associated, oncogene-regulated. | Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family. | 0.891 |
boc | ihha | ENSDARP00000098383 | ENSDARP00000076101 | BOC cell adhesion-associated, oncogene-regulated. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.910 |
boc | ihhb | ENSDARP00000098383 | ENSDARP00000076199 | BOC cell adhesion-associated, oncogene-regulated. | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. | 0.917 |
boc | shha | ENSDARP00000098383 | ENSDARP00000125090 | BOC cell adhesion-associated, oncogene-regulated. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.966 |
boc | shhb | ENSDARP00000098383 | ENSDARP00000056746 | BOC cell adhesion-associated, oncogene-regulated. | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. | 0.912 |
boc | smo | ENSDARP00000098383 | ENSDARP00000013486 | BOC cell adhesion-associated, oncogene-regulated. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.762 |
cdon | boc | ENSDARP00000081773 | ENSDARP00000098383 | Cell adhesion molecule-related/down-regulated by oncogenes. | BOC cell adhesion-associated, oncogene-regulated. | 0.911 |
cdon | dhh | ENSDARP00000081773 | ENSDARP00000053870 | Cell adhesion molecule-related/down-regulated by oncogenes. | Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family. | 0.917 |
cdon | ihha | ENSDARP00000081773 | ENSDARP00000076101 | Cell adhesion molecule-related/down-regulated by oncogenes. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.890 |
cdon | ihhb | ENSDARP00000081773 | ENSDARP00000076199 | Cell adhesion molecule-related/down-regulated by oncogenes. | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. | 0.914 |
cdon | shha | ENSDARP00000081773 | ENSDARP00000125090 | Cell adhesion molecule-related/down-regulated by oncogenes. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.983 |