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| | tomm34 | Translocase of outer mitochondrial membrane 34. (305 aa) |
| | tomm40 | Translocase of Outer mitochondrial membrane 40 homolog (Yeast). (344 aa) |
| | armc1 | Armadillo repeat-containing protein 1. (275 aa) |
| | acsl4a | Acyl-CoA synthetase long chain family member 4a. (706 aa) |
| | vdac2 | Voltage-dependent anion channel 2. (283 aa) |
| | pink1 | PTEN-induced kinase 1. (574 aa) |
| | acsl4b | Acyl-CoA synthetase long chain family member 4b. (671 aa) |
| | mtch2 | Mitochondrial carrier homolog 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa) |
| | mul1a | Mitochondrial ubiquitin ligase activator of nfkb 1-A; E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. (341 aa) |
| | baxa | BCL2-associated X, apoptosis regulator a. (192 aa) |
| | kmo | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (474 aa) |
| | dnajc11a | DnaJ (Hsp40) homolog, subfamily C, member 11a. (563 aa) |
| | miga1 | Mitoguardin 1; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of pld6/MitoPLD dimers. May act by regulating phospholipid metabolism via pld6/MitoPLD. (595 aa) |
| | bcl2l1 | Bcl-XL-like protein 1. (238 aa) |
| | myoc | Myocilin. (474 aa) |
| | mgst1.1 | Microsomal glutathione S-transferase 1.1. (154 aa) |
| | msto1 | Protein misato homolog 1; Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation; Belongs to the misato family. (591 aa) |
| | UBB | Si:ch211-202a12.4. (459 aa) |
| | bnip4 | BCL2-interacting protein 4. (177 aa) |
| | mao | Amine oxidase [flavin-containing]; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Oxidizes both 5-hydroxytryptamine (5-HT) and beta- phenylethylamine (PEA); Belongs to the flavin monoamine oxidase family. (522 aa) |
| | atad1a | ATPase family AAA domain-containing protein 1-A; ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Required for NMDA-stimulated AMPAR internalization in an ATPase-dependent manner (By similarity). (380 aa) |
| | bnip3la | BCL2/adenovirus E1B interacting protein 3-like, 2. (233 aa) |
| | sfxn2 | Sidoreflexin. (321 aa) |
| | march5l | E3 ubiquitin-protein ligase MARCHF5; Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. (289 aa) |
| | zgc:73226 | Zgc:73226. (187 aa) |
| | bnip3lb | BCL2-interacting protein 3-like b. (213 aa) |
| | acsl1a | Acyl-CoA synthetase long chain family member 1a. (697 aa) |
| | rtn4ip1 | Reticulon-4-interacting protein 1 homolog, mitochondrial; Plays a role in the regulation of retinal ganglion cell (RGC) maturation, neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury (By similarity). Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (387 aa) |
| | baxb | BCL2-associated X, apoptosis regulator b. (207 aa) |
| | mtx2 | Mtx2 protein. (274 aa) |
| | march5 | E3 ubiquitin-protein ligase MARCH5. (281 aa) |
| | letmd1 | LETM1 domain-containing 1. (362 aa) |
| | rnf185 | E3 ubiquitin-protein ligase RNF185; E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination. Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and [...] (194 aa) |
| | slc25a46 | Solute carrier family 25 member 46; May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission. (405 aa) |
| | dao.3 | D-amino-acid oxidase, tandem duplicate 3. (353 aa) |
| | dao.2 | D-amino-acid oxidase, tandem duplicate 2. (348 aa) |
| | pgam5 | Serine/threonine-protein phosphatase PGAM5, mitochondrial; Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics (By similarity). May be a central mediator for programmed necrosis (By similarity); Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (289 aa) |
| | mtx1b | Metaxin. (317 aa) |
| | mff | Mitochondrial fission factor homolog B; Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity); Belongs to the Tango11 family. (230 aa) |
| | fundc1 | FUN14 domain-containing protein 1; Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control; Belongs to the FUN14 family. (152 aa) |
| | rhot2 | Mitochondrial Rho GTPase 2; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity). (617 aa) |
| | qtrt1 | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (400 aa) |
| | vdac1 | Voltage-dependent anion channel 1. (283 aa) |
| | tomm22 | Translocase of Outer mitochondrial membrane 22 homolog (Yeast). (134 aa) |
| | tigarb | Fructose-2,6-bisphosphatase TIGAR B; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death. May p [...] (257 aa) |
| | fam210b | Family with sequence similarity 210 member B. (223 aa) |
| | cisd2 | CDGSH iron-sulfur domain-containing protein 2; Regulator of autophagy that contributes to antagonize becn1- mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity); Belongs to the CISD protein family. CISD2 subfamily. (135 aa) |
| | pgrmc1 | Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (179 aa) |
| | badb | BCL2-associated agonist of cell death b. (147 aa) |
| | vat1 | Synaptic vesicle membrane protein VAT-1 homolog. (484 aa) |
| | atad1b | ATPase family AAA domain-containing protein 1-B; ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Required for NMDA-stimulated AMPAR internalization in an ATPase-dependent manner (By similarity). (362 aa) |
| | usp30 | Ubiquitin carboxyl-terminal hydrolase 30; Deubiquitinating enzyme that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN). (491 aa) |
| | mul1b | Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa) |
| | cpt1b | Carnitine palmitoyltransferase 1B (muscle). (770 aa) |
| | cpt1aa | Carnitine palmitoyltransferase 1Aa (liver); Belongs to the carnitine/choline acetyltransferase family. (774 aa) |
| | pld6 | Mitochondrial cardiolipin hydrolase; Regulates mitochondrial shape through facilitating mitochondrial fusion. During spermatogenesis, plays a critical role in PIWI-interacting RNA (piRNA) biogenesis (By similarity). piRNAs provide essential protection against the activity of mobile genetic elements. piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation. Has been shown to be a backbone-non-specific, single strand-specific nuclease, cleavin [...] (227 aa) |
| | LOC100333227 | Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (789 aa) |
| | mief1 | Mitochondrial dynamics protein MID51; Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization (By similarity). (468 aa) |
| | abcb6a | ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (851 aa) |
| | tomm5 | Translocase of outer mitochondrial membrane 5 homolog (yeast). (51 aa) |
| | ppp1r15a | Protein phosphatase 1, regulatory subunit 15A. (319 aa) |
| | marc1 | Mitochondrial amidoxime-reducing component 1; Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transf [...] (325 aa) |
| | samm50 | Sorting and assembly machinery component 50 homolog A; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. (469 aa) |
| | tigara | Probable fructose-2,6-bisphosphatase TIGAR A; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell dea [...] (256 aa) |
| | mcl1a | MCL1 apoptosis regulator, BCL2 family member a. (255 aa) |
| | mtx1a | Metaxin. (319 aa) |
| | exd2 | Exonuclease 3'-5' domain-containing 2. (617 aa) |
| | cisd1 | CDGSH iron sulfur domain 1. (107 aa) |
| | zgc:110843 | Zgc:110843. (121 aa) |
| | vps13a | Vacuolar protein sorting 13 homolog A. (3217 aa) |
| | spata18 | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] (490 aa) |
| | mtor | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa) |
| | LOC100534669 | Uncharacterized protein. (166 aa) |
| | zmp:0000000991 | Zmp:0000000991. (1515 aa) |
| | bcl2l10 | BCL2-like 10 (Apoptosis facilitator). (176 aa) |
| | E7F1V5_DANRE | Uncharacterized protein. (344 aa) |
| | miga2 | Mitoguardin 2; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of pld6/MitoPLD dimers. May act by regulating phospholipid metabolism via pld6/MitoPLD. (596 aa) |
| | MFN1 | Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (438 aa) |
| | acsl1b | Acyl-CoA synthetase long chain family member 1b. (697 aa) |
| | bada | BCL2-associated agonist of cell death a. (145 aa) |
| | mtx3 | Metaxin-3; Could function in transport of proteins into the mitochondrion. (317 aa) |
| | dao.1 | D-amino-acid oxidase, tandem duplicate 1. (348 aa) |
| | acsl3b | Acyl-CoA synthetase long chain family member 3b. (711 aa) |
| | gdap1 | Ganglioside-induced differentiation-associated protein 1. (372 aa) |
| | qtrt2 | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (416 aa) |
| | mief2 | Mitochondrial elongation factor 2. (272 aa) |
| | akap1b | A kinase (PRKA) anchor protein 1b. (837 aa) |
| | tomm40l | Translocase of outer mitochondrial membrane 40 homolog,-like. (338 aa) |
| | mgst1.2 | Microsomal glutathione S-transferase 1.2. (152 aa) |
| | armc1l | Armadillo repeat-containing 1,-like. (273 aa) |
| | tomm70a | Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (579 aa) |
| | cfap70 | Cilia and flagella-associated protein 70. (1050 aa) |
| | F6P2T1_DANRE | Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (671 aa) |
| | gpat2 | Glycerol-3-phosphate acyltransferase 2, mitochondrial. (796 aa) |
| | podn | Podocan. (530 aa) |
| | zgc:110130 | Mitochondrial fission factor homolog A; Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity); Belongs to the Tango11 family. (286 aa) |
| | taz | Tafazzin family protein; Belongs to the taffazin family. (262 aa) |
| | bcl2a | B-cell leukemia/lymphoma 2. (228 aa) |
| | vdac3 | Voltage-dependent anion channel 3. (318 aa) |
| | akap1a | A kinase (PRKA) anchor protein 1a. (596 aa) |
| | abcb6b | ATP-binding cassette, sub-family B (MDR/TAP), member 6b. (627 aa) |
| | mfn2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | bokb | Bcl-2-related ovarian killer protein homolog B; May play a role in apoptosis. Does not appear to show pro- apoptotic activity when expressed ectopically in early embryos. Belongs to the Bcl-2 family. (214 aa) |
| | boka | Bcl-2-related ovarian killer protein homolog A; May play a role in apoptosis. Does not appear to show pro- apoptotic activity when expressed ectopically in early embryos. Belongs to the Bcl-2 family. (224 aa) |
| | acsl5 | Acyl-CoA synthetase long chain family member 5. (681 aa) |
| | mcl1b | MCL1 apoptosis regulator, BCL2 family member b. (228 aa) |
| | bcl2b | BCL2 apoptosis regulator b. (209 aa) |
| | cpt1cb | Carnitine palmitoyltransferase 1Cb; Belongs to the carnitine/choline acetyltransferase family. (780 aa) |
| | GK3P | Zgc:172295; Belongs to the FGGY kinase family. (534 aa) |
| | LOC100004321 | BCL2-associated X, apoptosis regulator a. (197 aa) |
| | cpt1ab | Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family. (774 aa) |
| | nlrx1 | NLR family member X1. (1005 aa) |
| | acsl3a | Acyl-CoA synthetase long chain family member 3a. (713 aa) |
| | gpam | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (826 aa) |
| | tomm6 | Translocase of outer mitochondrial membrane 6 homolog (yeast). (63 aa) |
| | pvrl2l | PVR cell adhesion molecule-related 2-like. (328 aa) |
| | tomm20b | Mitochondrial import receptor subunit TOM20 homolog B; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore (By similarity). (146 aa) |
| | ENSDARP00000132681 | Amine oxidase. (523 aa) |
| | myo19 | Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (573 aa) |
| | zgc:109986 | Zgc:109986. (306 aa) |
| | STMP1 | Short transmembrane mitochondrial protein 1; Belongs to the STMP1 family. (46 aa) |
| | LOC570939 | Uncharacterized protein. (606 aa) |
| | dnajc11 | DnaJ (Hsp40) homolog, subfamily C, member 11b. (560 aa) |
| | ENSDARP00000135461 | AMP-binding domain-containing protein. (426 aa) |
| | tomm7 | Translocase of outer mitochondrial membrane 7 homolog (yeast). (78 aa) |
| | znfx1 | Zinc finger, NFX1-type-containing 1. (1374 aa) |
| | fundc2 | Fun14 domain-containing 2. (147 aa) |
| | snn | Stannin. (87 aa) |
| | rab11fip5a | RAB11 family-interacting protein 5a (class I). (699 aa) |
| | zgc:153993 | Zgc:153993 protein. (204 aa) |
| | ubc | Ubiquitin C. (533 aa) |
| | bnip3 | BCL2-interacting protein 3. (183 aa) |
| | rhot1b | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (660 aa) |
| | mfn1b | Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (745 aa) |
| | ubb | Ubiquitin B. (610 aa) |
| | rhot1a | Mitochondrial Rho GTPase 1-A; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity). (619 aa) |
| | prkn | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (458 aa) |
| | dnm1l | Dynamin-1-like protein; Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. The specific recruitment at scission sites is mediated by membrane receptors like MFF, MIEF1 and MIEF2 for mitochondrial membranes. While the recruitment by the membrane receptors is GTP- dependent, the following hydrolysis of GTP induces the dissociation from the receptors and allows DNM1 [...] (715 aa) |
| | vps13c | Vacuolar protein sorting 13 homolog C. (3690 aa) |
| | ENSDARP00000145175 | USP domain-containing protein; Belongs to the peptidase C19 family. (338 aa) |
| | LOC100000713 | Uncharacterized protein. (265 aa) |
| | Acsl6 | AMP-binding domain-containing protein. (198 aa) |
| | ENSDARP00000148882 | Uncharacterized protein. (99 aa) |
| | zgc:56235 | Zgc:56235. (281 aa) |
| | hadhb | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (456 aa) |
| | bcl2l16 | BCL2-like 16. (199 aa) |
| | tomm20a | Translocase of outer mitochondrial membrane 20. (146 aa) |
| | aifm2 | Apoptosis-inducing factor mitochondria-associated 2. (373 aa) |
| | hax1 | HCLS1-associated protein X-1. (286 aa) |
| | acsl2 | Acyl-CoA synthetase long chain family member 2. (685 aa) |
| | samm50l | Sorting and assembly machinery component 50 homolog B; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. (469 aa) |
| | pi4kb | Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). (835 aa) |
