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| | thoc3 | THO complex 3. (322 aa) |
| | nutf2 | Novel protein similar to vertebrate nuclear transport factor 2 (NUTF2). (127 aa) |
| | cdk5 | Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | chtopa | Chromatin target of PRMT1a. (231 aa) |
| | akirin2 | Akirin 2. (180 aa) |
| | sarnp | SAP domain-containing ribonucleoprotein. (204 aa) |
| | nol6 | Nucleolar protein 6. (1153 aa) |
| | ctdspl2b | CTD small phosphatase-like protein 2-B; Probable phosphatase. (460 aa) |
| | ipo13 | Importin 13. (953 aa) |
| | ctdspl2a | CTD small phosphatase-like protein 2-A; Probable phosphatase. (469 aa) |
| | atxn1a | Ataxin 1a. (781 aa) |
| | rangap1a | RAN GTPase-activating protein 1a. (570 aa) |
| | alkbh5 | RNA demethylase ALKBH5; Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro) (By similarity). Requires molecular oxygen, alpha-ketoglutarate and iron. (352 aa) |
| | ppp3r1b | Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (170 aa) |
| | kpna5 | Importin subunit alpha-6; Functions in nuclear protein import; Belongs to the importin alpha family. (539 aa) |
| | eny2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (95 aa) |
| | thoc2 | THO complex 2. (1560 aa) |
| | lzts2b | Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (608 aa) |
| | polr2d | Polymerase (RNA) II (DNA directed) polypeptide D. (141 aa) |
| | malt1 | MALT paracaspase 1. (768 aa) |
| | appl2 | Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper-containing 2. (662 aa) |
| | nup214 | Nucleoporin 214. (1218 aa) |
| | cited1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (152 aa) |
| | xpo1a | Exportin 1 (CRM1 homolog, yeast) a. (1071 aa) |
| | ipo7 | Importin 7. (1039 aa) |
| | nop9 | Uncharacterized protein. (604 aa) |
| | zgc:85936 | Zgc:85936. (927 aa) |
| | dzip1 | Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. (897 aa) |
| | zc3h11a | Zinc finger CCCH-type-containing 11A. (794 aa) |
| | thoc1 | THO complex 1. (655 aa) |
| | ctdspl3 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 3. (360 aa) |
| | pom121 | POM121 transmembrane nucleoporin. (1201 aa) |
| | nup205 | Nucleoporin 205. (2001 aa) |
| | ran | GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] (215 aa) |
| | rpain | RPA-interacting protein. (225 aa) |
| | zgc:153681 | Zgc:153681. (610 aa) |
| | nfkbiaa | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa) |
| | nup98 | Nucleoporin 98. (1814 aa) |
| | ipo8 | Importin 8. (1024 aa) |
| | gle1 | Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity). (694 aa) |
| | chp1 | Calcineurin-like EF-hand protein 1. (194 aa) |
| | rrs1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (346 aa) |
| | iws1 | TFIIS N-terminal domain-containing protein. (778 aa) |
| | xpo4 | Exportin-4; Mediates the nuclear export of proteins (cargos) with broad substrate specificity; Belongs to the exportin family. (1150 aa) |
| | eif4enif1 | Eukaryotic translation initiation factor 4E nuclear import factor 1. (944 aa) |
| | nup62l | Nucleoporin 62-like. (507 aa) |
| | xpo6 | Exportin-6; Mediates the nuclear export of actin and profilin-actin complexes in somatic cells; Belongs to the exportin family. (1097 aa) |
| | strada | STE20-related adaptor alpha. (378 aa) |
| | ppp3r1a | Protein phosphatase 3, regulatory subunit B, alpha a. (170 aa) |
| | rsrc1 | Arginine/serine-rich coiled-coil 1. (308 aa) |
| | sqstm1 | Sequestosome 1. (452 aa) |
| | F6NWN8_DANRE | Si:dkey-29b11.3. (173 aa) |
| | npm1a | Nucleophosmin 1a. (279 aa) |
| | malt3 | MALT paracaspase 3. (627 aa) |
| | chtopb | Chromatin target of PRMT1b. (263 aa) |
| | tsc1b | TSC complex subunit 1b. (1228 aa) |
| | A5WV18_DANRE | Si:dkeyp-20g2.3. (174 aa) |
| | nf1b | Neurofibromin 1b. (2759 aa) |
| | adgrd1 | Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (359 aa) |
| | srsf3b | Serine and arginine-rich-splicing factor 3b. (164 aa) |
| | Q1LX65_DANRE | Si:ch211-216l23.2. (474 aa) |
| | elavl1a | ELAV-like protein; Belongs to the RRM elav family. (340 aa) |
| | kpna1 | Karyopherin alpha 1 (importin alpha 5). (589 aa) |
| | ipo11 | Importin 11. (961 aa) |
| | tgfb1b | Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa) |
| | F1QVK9_DANRE | Si:dkeyp-20g2.3. (188 aa) |
| | zgc:193690 | Zgc:193690. (492 aa) |
| | lzts2a | Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (741 aa) |
| | s100a1 | Protein S100; Belongs to the S-100 family. (96 aa) |
| | atxn1b | Ataxin 1b. (827 aa) |
| | gckr | Glucokinase (hexokinase 4) regulator. (281 aa) |
| | ftr52p | FinTRIM family, member 52, pseudogene. (664 aa) |
| | pkd1b | Polycystic kidney disease 1b. (3827 aa) |
| | X1WB88_DANRE | Si:ch73-182a11.2. (945 aa) |
| | srsf3a-2 | Serine and arginine rich splicing factor 3a. (174 aa) |
| | nf1a | Neurofibromin 1a. (2759 aa) |
| | traf3ip2l | TRAF3-interacting protein 2-like. (436 aa) |
| | abraa | Actin-binding Rho-activating protein a. (347 aa) |
| | aaas | Achalasia, adrenocortical insufficiency, alacrimia. (499 aa) |
| | nup54 | Nucleoporin 54. (353 aa) |
| | nup85 | Nuclear pore complex protein Nup85; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Involved in nephrogenesis (By similarity). (412 aa) |
| | hikeshi | Protein Hikeshi; Acts as a specific nuclear import carrier for hsp70 proteins following heat-shock stress: acts by mediating the nucleoporin- dependent translocation of ATP-bound hsp70 proteins into the nucleus. hsp70 proteins import is required to protect cells from heat shock damages (By similarity); Belongs to the OPI10 family. (197 aa) |
| | tsc2 | TSC complex subunit 2. (1674 aa) |
| | LOC108182745 | NFACT-R_1 domain-containing protein. (211 aa) |
| | poldip3 | Polymerase (DNA-directed), delta-interacting protein 3. (490 aa) |
| | lsg1 | Large subunit GTPase 1 homolog; GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity). (640 aa) |
| | ENSDARP00000135145 | Si:dkeyp-20g2.1. (762 aa) |
| | kpnb1 | Karyopherin (importin) beta 1. (876 aa) |
| | XPO5 | Si:ch211-233m11.2. (906 aa) |
| | ipo9 | Importin 9. (1043 aa) |
| | rangrf | Ran guanine nucleotide release factor; May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP. Plays a role in the regulation of the levels of GTP-bound RAN in the nucleus (By similarity). Required for normal expression of the ion channel hcn4 and for normal expression of the cardiac transcription factors nkx2.5, gata4 and hand2 during embryonic development. Required for normal embryonic heart development and normal heart rate. (183 aa) |
| | xpot | Exportin-T; Mediates the nuclear export of aminoacylated tRNAs. Belongs to the exportin family. (971 aa) |
| | gpn2 | GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (311 aa) |
| | alyref | Aly/REF export factor. (291 aa) |
| | xpo7 | Exportin 7. (1091 aa) |
| | tpra | Translocated promoter region a, nuclear basket protein. (2363 aa) |
| | nup153 | Nucleoporin 153. (1436 aa) |
| | sdad1 | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (682 aa) |
| | nxt2 | Nuclear transport factor 2-like export factor 2. (137 aa) |
| | LOC101886260 | Uncharacterized protein. (179 aa) |
| | nup160 | Nucleoporin 160. (1171 aa) |
| | Traf3ip2b | SEFIR domain-containing protein. (107 aa) |
| | ENSDARP00000147646 | Importin N-terminal domain-containing protein. (123 aa) |
| | xpo1b | Exportin 1 (CRM1 homolog, yeast) b. (1081 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (238 aa) |
| | wu:fj77h11 | Protein kinase domain-containing protein. (424 aa) |
| | nup37 | Nucleoporin 37. (326 aa) |
| | ENSDARP00000151541 | Uncharacterized protein. (232 aa) |
| | ENSDARP00000151732 | Nup54 domain-containing protein. (125 aa) |
| | RANBP2 | Si:ch1073-55a19.2. (2953 aa) |
| | ENSDARP00000153406 | DUF3384 domain-containing protein. (162 aa) |
| | appl1 | HESX homeobox 1. (718 aa) |
| | npm2b | Nucleophosmin/nucleoplasmin, 2b. (193 aa) |
| | ipo4 | Importin 4. (1110 aa) |
| | elavl1b | ELAV-like protein; Belongs to the RRM elav family. (360 aa) |
| | rangap1b | Ran GTPase-activating protein 1b. (576 aa) |
| | ankrd54 | Ankyrin repeat domain-containing protein 54; Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. (315 aa) |
| | nxf1 | Nuclear RNA export factor 1. (642 aa) |
| | sec13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa) |
| | fbxo22 | Novel protein with F-box domain. (385 aa) |
| | kpna3 | Importin subunit alpha; Belongs to the importin alpha family. (520 aa) |
| | ythdc1 | YTH domain-containing 1. (679 aa) |
| | spg11 | SPG11 vesicle-trafficking-associated, spatacsin. (1612 aa) |
| | tnpo3 | Transportin 3. (923 aa) |
| | FAM53C | LOC100002393 protein. (374 aa) |
| | kpna6 | Importin subunit alpha; Belongs to the importin alpha family. (537 aa) |
| | gpn3 | GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (285 aa) |
| | phax | Phosphorylated adaptor for RNA export. (379 aa) |
| | nup43 | Nucleoporin 43. (372 aa) |
| | TNPO2 | Transportin 2. (470 aa) |
| | tgfb1a | Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa) |
| | kpnb3 | Karyopherin (importin) beta 3. (1093 aa) |
| | pttg1ipb | Pituitary tumor-transforming 1 interacting protein. (172 aa) |
| | thoc5 | THO complex subunit 5 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity); Belongs to t [...] (684 aa) |
| | tnpo2 | Transportin 2 (Importin 3, Karyopherin beta 2b). (889 aa) |
| | kpna2 | Importin subunit alpha; Belongs to the importin alpha family. (525 aa) |
| | thoc6 | THO complex subunit 6 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity); Belongs to t [...] (323 aa) |
| | npm1b | Nucleophosmin 1b. (329 aa) |
| | txnipa | Thioredoxin-interacting protein a. (400 aa) |
| | heatr3 | HEAT repeat-containing 3. (682 aa) |
| | ddx39b | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B. (435 aa) |
| | tnpo1 | Transportin 1. (891 aa) |
| | nup42 | Nucleoporin NUP42; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. (414 aa) |
| | desi1a | PPPDE peptidase domain containing 2a. (169 aa) |
| | abrab | Actin-binding Rho-activating protein b. (359 aa) |
| | nup188 | Nucleoporin 188. (1732 aa) |
| | ssb | Small RNA-binding exonuclease protection factor La. (401 aa) |
| | nup107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (919 aa) |
| | pkd1a | Polycystic kidney disease 1a. (4346 aa) |
| | kpna4 | Importin subunit alpha; Belongs to the importin alpha family. (521 aa) |
| | kpna7 | Importin subunit alpha; Belongs to the importin alpha family. (520 aa) |
| | htatip2 | HIV-1 Tat interactive protein 2. (236 aa) |
| | srsf3a | Serine and arginine-rich-splicing factor 3a. (174 aa) |
| | tsc1a | TSC complex subunit 1a. (1128 aa) |
| | nup35 | Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity); Belongs to the Nup35 family. (308 aa) |
| | sem1 | SEM1 26S proteasome complex subunit. (92 aa) |
| | styx | Serine/threonine/tyrosine-interacting protein. (224 aa) |
| | nup88 | Nucleoporin 88; Component of the nuclear pore complex. (720 aa) |
| | nup133 | Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport (By similarity). Involved in nephrogenesis. (1136 aa) |
| | nup58 | Nucleoporin 58. (567 aa) |
| | cse1l | Exportin-2; Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity). Negatively regulates fluid secretion and plays a role in fluid homeostasis by downregulating cftr activity. (971 aa) |
| | anp32a | Acidic leucine-rich nuclear phosphoprotein 32 family member A; Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. (254 aa) |
| | thoc7 | THO complex subunit 7 homolog; Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre- mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm v [...] (202 aa) |
| | ncbp2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (155 aa) |
| | fam53b | Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (ctnnb1) nuclear localization. Required for appendage regeneration by regulating cell proliferation. (379 aa) |
| | malt2 | MALT paracaspase 2. (806 aa) |
| | tprb | Translocated promoter region b, nuclear basket protein. (2352 aa) |
| | mcm3ap | Minichromosome maintenance complex component 3-associated protein. (2118 aa) |
| | tmco6 | Transmembrane and coiled-coil domains 6. (504 aa) |
| | ltv1 | Protein LTV1 homolog; Belongs to the LTV1 family. (473 aa) |
| | nup50 | Nucleoporin 50. (422 aa) |
| | snupn | Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family. (365 aa) |
| | eif6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa) |
| | nfkbiab | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (312 aa) |
| | rae1 | mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Belongs to the WD repeat rae1 family. (368 aa) |
| | nup93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. (820 aa) |
| | smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) |
| | nmd3 | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (505 aa) |
| | abce1 | ATP-binding cassette, sub-family E (OABP), member 1. (599 aa) |
| | ddx39ab | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab. (427 aa) |
| | pcid2 | PCI domain-containing protein 2; Belongs to the CSN12 family. (399 aa) |
| | ddx39aa | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa. (427 aa) |
| | nup155 | Nucleoporin 155. (1391 aa) |
| | hspa9 | Heat shock protein 9; Belongs to the heat shock protein 70 family. (682 aa) |
| | ddx19 | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast). (487 aa) |
| | pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa) |
