STRINGSTRING
ythdf1 ythdf1 btg2 btg2 tnr tnr fosl1a fosl1a dkk1a dkk1a uts1 uts1 ctns ctns tsc1a tsc1a F1QSV1_DANRE F1QSV1_DANRE nptnb nptnb vdac1 vdac1 dkk1b dkk1b htt htt srfa srfa ube3a ube3a npas4a npas4a cdk5 cdk5 atxn1a atxn1a shank3a shank3a LOC110437736 LOC110437736 hmgcra hmgcra ppp1r1b ppp1r1b neto1l neto1l rapgef3 rapgef3 adcy3a adcy3a atxn1l atxn1l mecp2 mecp2 cica cica en1b en1b npas4b npas4b cicb cicb shank3b shank3b taco1 taco1 shank2b shank2b tsc1b tsc1b nf1b nf1b fosl1b fosl1b adcy3b adcy3b epm2a epm2a atxn1b atxn1b cln8 cln8 shank1 shank1 nf1a nf1a X1WGX6_DANRE X1WGX6_DANRE aaas aaas appa appa tanc1b tanc1b hmgcrb hmgcrb srfb srfb EIF2AK4 EIF2AK4 nptna nptna ENSDARP00000137923 ENSDARP00000137923 LOC100534805 LOC100534805 zzef1 zzef1 prkn prkn slc7a11 slc7a11 ENSDARP00000142835 ENSDARP00000142835 shank2a shank2a nptx2a nptx2a Reln Reln lgmn lgmn cntn2 cntn2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ythdf1YTH N(6)-methyladenosine RNA-binding protein 1. (614 aa)
btg2Anti-proliferative cofactor. (165 aa)
tnrTenascin R (Restrictin, janusin). (1350 aa)
fosl1aFOS-like 1, AP-1 transcription factor subunit a. (346 aa)
dkk1aDickkopf WNT-signaling pathway inhibitor 1a. (256 aa)
uts1Urotensin 1. (138 aa)
ctnsCystinosin, lysosomal cystine transporter. (384 aa)
tsc1aTSC complex subunit 1a. (1128 aa)
F1QSV1_DANRESi:ch73-352p4.8. (492 aa)
nptnbNeuroplastin b. (403 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
dkk1bDickkopf WNT-signaling pathway inhibitor 1b. (241 aa)
httHuntingtin. (3121 aa)
srfaSerum response factor a. (539 aa)
ube3aUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (857 aa)
npas4aNeuronal PAS domain-containing protein 4A; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late- response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal act [...] (933 aa)
cdk5Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
atxn1aAtaxin 1a. (781 aa)
shank3aSH3 and multiple ankyrin repeat domains 3a. (1509 aa)
LOC110437736Neuropilin (NRP) and tolloid (TLL)-like 1. (523 aa)
hmgcra3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
ppp1r1bProtein phosphatase 1, regulatory (inhibitor) subunit 1B. (189 aa)
neto1lNeuropilin (NRP) and tolloid (TLL)-like 1, like. (539 aa)
rapgef3Rap guanine nucleotide exchange factor (GEF) 3. (867 aa)
adcy3aAdenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
atxn1lAtaxin 1-like. (765 aa)
mecp2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (524 aa)
cicaCapicua transcriptional repressor a. (2492 aa)
en1bHomeobox protein engrailed-like. (274 aa)
npas4bNeuronal PAS domain-containing protein 4B; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late- response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal act [...] (538 aa)
cicbCapicua transcriptional repressor b. (2623 aa)
shank3bSH3 and multiple ankyrin repeat domains 3b. (1631 aa)
taco1Translational activator of mitochondrially encoded cytochrome c oxidase I. (308 aa)
shank2bSH3 and multiple ankyrin repeat domains 2b. (1800 aa)
tsc1bTSC complex subunit 1b. (1228 aa)
nf1bNeurofibromin 1b. (2759 aa)
fosl1bFOS-like 1, AP-1 transcription factor subunit b. (200 aa)
adcy3bAdenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1071 aa)
epm2aEPM2A glucan phosphatase, laforin. (310 aa)
atxn1bAtaxin 1b. (827 aa)
cln8CLN8 transmembrane ER and ERGIC protein. (289 aa)
shank1SH3 and multiple ankyrin repeat domains 1. (852 aa)
nf1aNeurofibromin 1a. (2759 aa)
X1WGX6_DANRESi:ch73-330k17.3. (221 aa)
aaasAchalasia, adrenocortical insufficiency, alacrimia. (499 aa)
appaAmyloid beta (A4) precursor protein a. (194 aa)
tanc1bTetratricopeptide repeat, ankyrin repeat and coiled-coil-containing 1b. (1766 aa)
hmgcrb3-hydroxy-3-methylglutaryl coenzyme A reductase. (844 aa)
srfbSerum response factor b. (260 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1355 aa)
nptnaZgc:162565 protein. (277 aa)
ENSDARP00000137923Si:ch1073-303k11.2. (266 aa)
LOC100534805Translational activator of mitochondrially encoded cytochrome c oxidase I. (308 aa)
zzef1Zinc finger, ZZ-type with EF hand domain 1. (3038 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (458 aa)
slc7a11Solute carrier family 7 member 11. (498 aa)
ENSDARP00000142835Si:dkey-23i12.7. (158 aa)
shank2aSH3 and multiple ankyrin repeat domains 2a. (1306 aa)
nptx2aNeuronal pentraxin 2a. (433 aa)
RelnReelin domain-containing protein. (259 aa)
lgmnLegumain. (438 aa)
cntn2Contactin 2. (1040 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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