STRINGSTRING
phf24 phf24 btg2 btg2 bdkrb1 bdkrb1 tnfrsf1a tnfrsf1a fosl1a fosl1a nfkbiab nfkbiab gclc gclc mdkb mdkb uts1 uts1 mkks mkks jupa jupa pkd2 pkd2 tcap tcap bnip4 bnip4 slc26a5 slc26a5 aqp1a.1 aqp1a.1 zgc:73226 zgc:73226 pkd1a pkd1a serpine2 serpine2 ptk2ab ptk2ab hpn hpn tmc2b tmc2b tmem120a tmem120a mdka mdka fer1l6 fer1l6 bag3 bag3 ptk2bb ptk2bb xpc xpc p2rx7 p2rx7 jun jun tmc2a tmc2a htt htt irf1a irf1a scel scel badb badb LOC795766 LOC795766 fas fas jupb jupb kcnq1.1 kcnq1.1 ptger4b ptger4b f11r.2 f11r.2 TMC1 TMC1 ptger4a ptger4a casp8 casp8 trpa1b trpa1b zgc:171750 zgc:171750 ankrd1a ankrd1a ptger4c ptger4c tbc1d31 tbc1d31 f11r.1 f11r.1 dlx5a dlx5a get1 get1 piezo1 piezo1 map2k4b map2k4b whrna whrna B0S6V5_DANRE B0S6V5_DANRE tlr7 tlr7 pkd1l2b pkd1l2b map2k4a map2k4a tlr8a tlr8a tmem132e tmem132e casp2 casp2 zgc:171474 zgc:171474 nfkbiaa nfkbiaa aqp1a.2 aqp1a.2 bada bada zgc:171977 zgc:171977 lrriq1 lrriq1 cd40 cd40 ptprq ptprq zgc:173856 zgc:173856 zgc:152652 zgc:152652 F1QYL7_DANRE F1QYL7_DANRE otofa otofa p2rx3b p2rx3b E9QHQ1_DANRE E9QHQ1_DANRE pkd2l1 pkd2l1 trpa1a trpa1a whrnb whrnb fosl1b fosl1b tmem150c tmem150c otofb otofb pjvk pjvk map3k14a map3k14a gsdmea gsdmea ptk2ba ptk2ba pkd1b pkd1b pkd1l2b-2 pkd1l2b-2 ptk2aa ptk2aa kcnk4a kcnk4a si:dkey-11f4.7 si:dkey-11f4.7 LOC100332583 LOC100332583 chek1 chek1 june june casp20 casp20 casp22 casp22 map3k1 map3k1 gadd45ab gadd45ab ENSDARP00000137251 ENSDARP00000137251 csrp3 csrp3 slitrk6 slitrk6 zgc:153993 zgc:153993 pdzd7a pdzd7a fadd fadd bnip3 bnip3 ptn ptn bglapl bglapl il1b il1b irf1b irf1b kcnq1.2 kcnq1.2 ENSDARP00000142154 ENSDARP00000142154 ENSDARP00000142279 ENSDARP00000142279 ENSDARP00000142835 ENSDARP00000142835 ENSDARP00000144057 ENSDARP00000144057 eng eng LOC100334952 LOC100334952 tomt tomt pkd1l2a pkd1l2a ENSDARP00000149019 ENSDARP00000149019 casp10 casp10 strc1 strc1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phf24PHD finger protein 24. (409 aa)
btg2Anti-proliferative cofactor. (165 aa)
bdkrb1Bradykinin receptor B1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (389 aa)
fosl1aFOS-like 1, AP-1 transcription factor subunit a. (346 aa)
nfkbiabNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (312 aa)
gclcGlutamate-cysteine ligase, catalytic subunit. (631 aa)
mdkbMidkine-related growth factor Mdk2. (147 aa)
uts1Urotensin 1. (138 aa)
mkksMcKusick-Kaufman syndrome. (563 aa)
jupaJunction plakoglobin a. (729 aa)
pkd2Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel (By similarity). Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades. May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By simila [...] (904 aa)
tcapTitin-cap (telethonin). (179 aa)
bnip4BCL2-interacting protein 4. (177 aa)
slc26a5Solute carrier family 26, member 5. (739 aa)
aqp1a.1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (260 aa)
zgc:73226Zgc:73226. (187 aa)
pkd1aPolycystic kidney disease 1a. (4346 aa)
serpine2Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (395 aa)
ptk2abProtein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1050 aa)
hpnNovel protein similar to H.sapiens HPN, hepsin (Transmembrane protease, serine 1) (HPN); Belongs to the peptidase S1 family. (425 aa)
tmc2bTransmembrane channel-like protein 2-B; Belongs to the TMC family. (892 aa)
tmem120aTransmembrane protein 120A; May play a role in adipogenesis. Belongs to the TMEM120 family. (341 aa)
mdkaMidkine-related growth factor Mdk1. (146 aa)
fer1l6Fer-1-like family member 6. (1790 aa)
bag3BCL2-associated athanogene 3. (480 aa)
ptk2bbProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1004 aa)
xpcXeroderma pigmentosum, complementation group C. (879 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (308 aa)
tmc2aTransmembrane channel-like protein 2-A; Probable ion channel required for the normal function of hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machinery. Involved in mechanosensitive responses of the hair cells. (916 aa)
httHuntingtin. (3121 aa)
irf1aInterferon regulatory factor. (251 aa)
scelSciellin. (612 aa)
badbBCL2-associated agonist of cell death b. (147 aa)
LOC795766ADP-ribosylation factor 2b. (783 aa)
fasFas cell surface death receptor. (293 aa)
jupbJunction plakoglobin b. (726 aa)
kcnq1.1Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (655 aa)
ptger4bProstaglandin E receptor 4 (subtype EP4) b; Belongs to the G-protein coupled receptor 1 family. (497 aa)
f11r.2F11 receptor, tandem duplicate 2. (294 aa)
TMC1Transmembrane channel-like protein 1; Probable ion channel required for the normal function of hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machinery ; Belongs to the TMC family. (990 aa)
ptger4aProstaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (403 aa)
casp8Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (476 aa)
trpa1bTransient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1120 aa)
zgc:171750Zgc:171750. (847 aa)
ankrd1aAnkyrin repeat domain 1a (cardiac muscle). (317 aa)
ptger4cProstaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (435 aa)
tbc1d31TBC1 domain family, member 31. (1070 aa)
f11r.1F11 receptor, tandem duplicate 1. (292 aa)
dlx5aHomeobox protein Dlx5a; Belongs to the distal-less homeobox family. (282 aa)
get1Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail-anchored (TA) proteins into the ER membrane. (170 aa)
piezo1Piezo-type mechanosensitive ion channel component. (2436 aa)
map2k4bMitogen-activated protein kinase kinase 4B; Belongs to the protein kinase superfamily. (417 aa)
whrnaWhirlin a. (939 aa)
B0S6V5_DANRESi:dkey-10c21.1. (254 aa)
tlr7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1045 aa)
pkd1l2bPolycystic kidney disease 1-like 2b. (1901 aa)
map2k4aMitogen-activated protein kinase kinase 4A; Belongs to the protein kinase superfamily. (404 aa)
tlr8aToll-like receptor 8a; Belongs to the Toll-like receptor family. (1009 aa)
tmem132eTransmembrane protein 132E; Required for normal inner ear hair cell function and hearing. (1073 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (399 aa)
zgc:171474Zgc:171474. (847 aa)
nfkbiaaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa)
aqp1a.2Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
badaBCL2-associated agonist of cell death a. (145 aa)
zgc:171977Zgc:171977. (804 aa)
lrriq1Leucine-rich repeats and IQ motif-containing 1. (1291 aa)
cd40CD40 molecule, TNF receptor superfamily member 5. (286 aa)
ptprqProtein tyrosine phosphatase receptor type Q. (2301 aa)
zgc:173856Zgc:173856. (805 aa)
zgc:152652Zgc:152652. (807 aa)
F1QYL7_DANRESi:ch211-193k19.1. (967 aa)
otofaOtoferlin; Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses. (1992 aa)
p2rx3bP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)
E9QHQ1_DANRESi:ch211-146l10.7. (850 aa)
pkd2l1Polycystic kidney disease 2-like 1. (790 aa)
trpa1aTransient receptor potential cation channel, subfamily A, member 1a. (1126 aa)
whrnbWhirlin b. (946 aa)
fosl1bFOS-like 1, AP-1 transcription factor subunit b. (200 aa)
tmem150cTransmembrane protein 150C. (247 aa)
otofbOtoferlin b. (1773 aa)
pjvkPejvakin. (361 aa)
map3k14aMitogen-activated protein kinase kinase kinase 14a. (825 aa)
gsdmeaGasdermin Ea. (521 aa)
ptk2baProtein tyrosine kinase 2 beta, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (933 aa)
pkd1bPolycystic kidney disease 1b. (3827 aa)
pkd1l2b-2Polycystic kidney disease 1-like 2b. (859 aa)
ptk2aaProtein tyrosine kinase 2aa. (977 aa)
kcnk4aPotassium channel, subfamily K, member 4a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (542 aa)
si:dkey-11f4.7Si:dkey-11f4.7. (324 aa)
LOC100332583TIR domain-containing protein; Belongs to the Toll-like receptor family. (1009 aa)
chek1CHK1 checkpoint homolog (S. pombe); Belongs to the protein kinase superfamily. (410 aa)
juneJunE proto-oncogene, AP-1 transcription factor subunit. (323 aa)
casp20Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (347 aa)
casp22Caspase 22, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (376 aa)
map3k1Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1334 aa)
gadd45abGrowth arrest and DNA-damage-inducible, alpha, b. (156 aa)
ENSDARP00000137251Si:ch73-215d9.1. (1037 aa)
csrp3Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
slitrk6SLIT and NTRK-like family, member 6. (830 aa)
zgc:153993Zgc:153993 protein. (204 aa)
pdzd7aPDZ domain-containing 7a. (954 aa)
faddFas (tnfrsf6)-associated via death domain. (192 aa)
bnip3BCL2-interacting protein 3. (183 aa)
ptnPleiotrophin. (158 aa)
bglaplOsteocalcin; Binds strongly to apatite and calcium. (182 aa)
il1bInterleukin-1. (284 aa)
irf1bInterferon regulatory factor. (287 aa)
kcnq1.2Potassium voltage-gated channel, KQT-like subfamily, member 1.2; Belongs to the potassium channel family. (531 aa)
ENSDARP00000142154Si:ch211-146l10.8. (858 aa)
ENSDARP00000142279Transmembrane channel-like protein. (536 aa)
ENSDARP00000142835Si:dkey-23i12.7. (158 aa)
ENSDARP00000144057Piezo type mechanosensitive ion channel component 2. (1353 aa)
engEndoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Important for endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. (542 aa)
LOC100334952Piezo-type mechanosensitive ion channel component. (2622 aa)
tomtTransmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. (259 aa)
pkd1l2aPolycystic kidney disease 1-like 2a. (2484 aa)
ENSDARP00000149019Piezo_RRas_bdg domain-containing protein. (587 aa)
casp10Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (548 aa)
strc1Stereocilin 1. (2032 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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