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| | sh3tc2 | SH3 domain and tetratricopeptide repeats 2. (1407 aa) |
| | cdh2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa) |
| | sox9a | HMG box transcription factor Sox9a. (462 aa) |
| | foxa2 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. (409 aa) |
| | smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) |
| | eif2b3 | Eukaryotic translation initiation factor 2B, subunit 3 gamma. (453 aa) |
| | mdkb | Midkine-related growth factor Mdk2. (147 aa) |
| | fgf8a | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. (210 aa) |
| | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6. (381 aa) |
| | dag1 | Dystroglycan 1. (866 aa) |
| | phgdh | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | mettl3 | N6-adenosine-methyltransferase subunit METTL3; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some RNAs and regulates various processes such as the circadian clock, differentiation of embryonic and hematopoietic stem cells, cortical neurogenesis, response to DNA damage, differentiation of T-cells and primary miRNA processing. In the heterodimer formed with mettl14, mettl3 constitutes the catalytic core (By similarity). N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some [...] (584 aa) |
| | pes | Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (583 aa) |
| | itgb4 | Integrin beta. (1893 aa) |
| | nkx6.1 | NK6 homeobox 1. (312 aa) |
| | prdm8 | PR domain-containing 8. (502 aa) |
| | c1qa | Complement component 1, q subcomponent, A chain. (247 aa) |
| | abl2 | Tyrosine-protein kinase. (1135 aa) |
| | tspan2a | Tetraspanin. (211 aa) |
| | dctn2 | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity). (405 aa) |
| | ttc21b | Tetratricopeptide repeat domain 21B. (1321 aa) |
| | xpr1b | Xenotropic and polytropic retrovirus receptor 1 homolog; Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho- inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules (By similarity). (693 aa) |
| | notch1b | Notch receptor 1b. (2465 aa) |
| | fgf5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa) |
| | plp1b | Proteolipid protein 1b. (279 aa) |
| | mdka | Midkine-related growth factor Mdk1. (146 aa) |
| | acy3.1 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) A; Plays an important role in deacetylating mercapturic acids in kidney proximal tubules; Belongs to the AspA/AstE family. Aspartoacylase subfamily. (328 aa) |
| | gpr157 | G protein-coupled receptor 157. (325 aa) |
| | shhb | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. (416 aa) |
| | eif2b2 | Eukaryotic translation initiation factor 2B, subunit 2 beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (355 aa) |
| | tgfb1a | Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa) |
| | fgf16 | Fibroblast growth factor 16; Plays a crucial role in pectoral fin bud outgrowth. Belongs to the heparin-binding growth factors family. (203 aa) |
| | egr2b | Early growth response protein 2b; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. (412 aa) |
| | sox9b | HMG box transcription factor Sox9b. (407 aa) |
| | aspa | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate; Belongs to the AspA/AstE family. Aspartoacylase subfamily. (315 aa) |
| | dusp10 | Dual-specificity phosphatase 10. (459 aa) |
| | vtnb | Vitronectin b. (449 aa) |
| | leo1 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. (696 aa) |
| | vtna | Vitronectin a. (514 aa) |
| | egr2a | Early growth response 2a. (393 aa) |
| | cdk5 | Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | ilk | Integrin-linked kinase. (452 aa) |
| | ihha | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa) |
| | ihhb | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. (412 aa) |
| | plpp3 | Phospholipid phosphatase 3. (312 aa) |
| | crb2a | Crumbs cell polarity complex component 2a. (1466 aa) |
| | gpr17 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (339 aa) |
| | mxra8b | Matrix-remodelling-associated 8b. (434 aa) |
| | mxra8a | Matrix-remodelling-associated 8a. (447 aa) |
| | xpr1a | Xenotropic and polytropic retrovirus receptor 1a. (692 aa) |
| | wasf3b | WASP family member 3b. (481 aa) |
| | ppp3r1b | Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (170 aa) |
| | zgc:109889 | Zgc:109889 protein. (279 aa) |
| | mettl14 | N6-adenosine-methyltransferase non-catalytic subunit; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. (455 aa) |
| | pick1 | Protein-interacting with prkca 1. (406 aa) |
| | nrros | Transforming growth factor beta activator LRRC33; Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1. TGF- beta-1 activation mediated by lrrc33/nrros is highly localized: there is little spreading of TGF-beta-1 activated from one microglial cell to neighbo [...] (685 aa) |
| | nab2 | NGFI-A-binding protein 2 (EGR1 binding protein 2). (491 aa) |
| | eif2b5 | Eukaryotic translation initiation factor 2B, subunit 5 epsilon. (607 aa) |
| | sox10 | HMG-box transcription factor Sox10. (485 aa) |
| | ror2 | Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (939 aa) |
| | abcd1 | ATP-binding cassette sub-family D member 1; Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis (By similarity). Involved in oligodendrocyte patterning and myelination. (766 aa) |
| | SH3TC1 | SH3 domain and tetratricopeptide repeats 1. (1322 aa) |
| | eif2b4 | Eukaryotic translation initiation factor 2B, subunit 4 delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (540 aa) |
| | fa2h | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (377 aa) |
| | adgrg2a | Adhesion G protein-coupled receptor G2a; Belongs to the G-protein coupled receptor 2 family. (1037 aa) |
| | prdm8b | PR domain-containing 8b. (570 aa) |
| | acy3.2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) B; Plays an important role in deacetylating mercapturic acids in kidney proximal tubules; Belongs to the AspA/AstE family. Aspartoacylase subfamily. (314 aa) |
| | pard3ab | Par-3 family cell polarity regulator alpha, b. (1332 aa) |
| | gle1 | Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity). (694 aa) |
| | wasf3a | WASP family member 3a. (433 aa) |
| | ercc2 | Excision repair cross-complementation group 2. (760 aa) |
| | lef1 | Lymphocyte enhancer binding factor 1 Lef1. (365 aa) |
| | phox2ba | Paired-like homeobox 2Ba. (155 aa) |
| | ppp3r1a | Protein phosphatase 3, regulatory subunit B, alpha a. (170 aa) |
| | adgrg6 | Adhesion G-protein coupled receptor G6; G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins. Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Plays also a role in inner ear development. (1240 aa) |
| | cdkn2c | Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (170 aa) |
| | ror1 | Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (950 aa) |
| | E9QHS4_DANRE | Si:dkey-175m17.7. (892 aa) |
| | nf1b | Neurofibromin 1b. (2759 aa) |
| | F1QB00_DANRE | Si:dkey-259j3.5; Belongs to the G-protein coupled receptor 2 family. (720 aa) |
| | adgrg4b | Adhesion G protein-coupled receptor G4b; Belongs to the G-protein coupled receptor 2 family. (522 aa) |
| | tgfb1b | Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa) |
| | cspg5a | Chondroitin sulfate proteoglycan 5a. (532 aa) |
| | abl1 | Tyrosine-protein kinase. (1081 aa) |
| | shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) |
| | I3ITM8_DANRE | Si:ch73-362m14.4. (501 aa) |
| | nf1a | Neurofibromin 1a. (2759 aa) |
| | ptprz1a | Protein tyrosine phosphatase receptor type Z1a. (1837 aa) |
| | phox2bb | Paired-like homeobox 2Bb. (284 aa) |
| | appa | Amyloid beta (A4) precursor protein a. (194 aa) |
| | nkx2.2b | NK2 transcription factor related 2b. (237 aa) |
| | crb2b | Crumbs cell polarity complex component 2b. (1010 aa) |
| | dner | Delta/notch-like EGF repeat-containing. (744 aa) |
| | fgf3 | Fibroblast growth factor 3; Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Belongs to the heparin-binding growth factors family. (256 aa) |
| | mib1 | E3 ubiquitin-protein ligase mib1; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It thereby participates in many processes regulated by the Notch signaling pathway, such as midline cell fate specification prior to germ layer formation, patterning of sensory cell differentiation in the ear, neurogenesis of the hindbrain and commitment to a secretory fate in the intesti [...] (1041 aa) |
| | ENSDARP00000134315 | Si:dkeyp-41f9.4. (398 aa) |
| | plp1a | Proteolipid protein 1a. (245 aa) |
| | crb1 | Crumbs cell polarity complex component 1. (1428 aa) |
| | ENSDARP00000136668 | Ncstrn_small domain-containing protein. (599 aa) |
| | notch1a | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2438 aa) |
| | nkx6.2 | NK6 homeobox 2. (278 aa) |
| | adgrg4a | Adhesion G protein-coupled receptor G4a; Belongs to the G-protein coupled receptor 2 family. (1201 aa) |
| | znf16l | Zinc finger protein 16-like; Probable transcription factor (Probable). Important for development and migration of oligodendrocyte precursor cells, and normal myelination of axons in the central nervous system (CNS). Functions autonomously in oligodendrocytes to promote CNS myelination. Seems to act in parallel with notch3 during oligodendrocyte development. Belongs to the krueppel C2H2-type zinc-finger protein family. (528 aa) |
| | ptprz1b | Protein tyrosine phosphatase receptor type Z1b. (1303 aa) |
| | tenm4 | Teneurin-4; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May play a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation of oligodendrocytes and myelination of axons. May function as a cellular signal transducer (By similarity). Belongs to the tenascin family. Teneurin subfamily. (2865 aa) |
| | Reln | Reelin domain-containing protein. (259 aa) |
| | tspan2b | Tetraspanin. (227 aa) |
| | csf1ra | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] (977 aa) |
| | cnp | 2',3'-cyclic nucleotide 3' phosphodiesterase. (443 aa) |
| | cntn2 | Contactin 2. (1040 aa) |
| | ENSDARP00000151567 | Uncharacterized protein. (108 aa) |
| | nkx2.2a | Homeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). (273 aa) |
| | PARD3 | Par-3 family cell polarity regulator. (531 aa) |
| | eif2b1 | Eukaryotic translation initiation factor 2B, subunit 1 alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (291 aa) |
