STRINGSTRING
gsk3aa gsk3aa fosb fosb Q5RHR2_DANRE Q5RHR2_DANRE plekha1b plekha1b ccl19b ccl19b cat cat ryr2b ryr2b gphnb gphnb lonp1 lonp1 pam pam stk24b stk24b slc25a12 slc25a12 june june gphna gphna cpne9 cpne9 syt7b syt7b B8JJU9_DANRE B8JJU9_DANRE guca1e guca1e ENSDARP00000136668 ENSDARP00000136668 glrx2 glrx2 atrxl atrxl cygb1 cygb1 cpne4a cpne4a mef2cb mef2cb mtr mtr cyp1c1 cyp1c1 homer1b homer1b dhx36 dhx36 zgc:153993 zgc:153993 bnip3 bnip3 cpne3 cpne3 cpne4b cpne4b syt12 syt12 cpne7 cpne7 prkn prkn syt1a syt1a kdm6ba kdm6ba ENSDARP00000142835 ENSDARP00000142835 cpne5b cpne5b adamts13 adamts13 ankzf1 ankzf1 ENSDARP00000147747 ENSDARP00000147747 lgmn lgmn park7 park7 ENSDARP00000150504 ENSDARP00000150504 impact impact blm blm ENSDARP00000153250 ENSDARP00000153250 p2rx1 p2rx1 syt15 syt15 LOC101884989 LOC101884989 CPNE8 CPNE8 syt6b syt6b mtf1 mtf1 RYR2 RYR2 fxn fxn mef2aa mef2aa ENSDARP00000117118 ENSDARP00000117118 cpne5a cpne5a selenow1 selenow1 itpkcb itpkcb selenow2b selenow2b dnmt3bb.3 dnmt3bb.3 carf carf pkd2l1 pkd2l1 ercc6 ercc6 trpa1a trpa1a mapk7 mapk7 itpkca itpkca A2BIG0_DANRE A2BIG0_DANRE selenom selenom aifm1 aifm1 ccs ccs ryr1a ryr1a fosl1a fosl1a glra3 glra3 kdm6bb kdm6bb zgc:63972 zgc:63972 bcl2a bcl2a eif2ak3 eif2ak3 F1QB29_DANRE F1QB29_DANRE syt2a syt2a fosl1b fosl1b syt5a syt5a selenow2a selenow2a itpkb itpkb abcb6b abcb6b syt10 syt10 tnfaip3 tnfaip3 stk25a stk25a zc3h12a zc3h12a znf277 znf277 smpd1 smpd1 ednrbb ednrbb setx setx bcl2b bcl2b syt3 syt3 atp7b atp7b syt7a syt7a ddi2 ddi2 E7FC63_DANRE E7FC63_DANRE ryr3 ryr3 stk24a stk24a junbb junbb slc25a13 slc25a13 creb1b creb1b ENSDARP00000132536 ENSDARP00000132536 slc30a10 slc30a10 slc30a8 slc30a8 plekha1a plekha1a smpd3 smpd3 syt5b syt5b syt13 syt13 ripk1l ripk1l pink1 pink1 kcnmb2 kcnmb2 fgb fgb E7FF92_DANRE E7FF92_DANRE gclc gclc bsg bsg guca1a guca1a adgrv1 adgrv1 hsp90aa1.1 hsp90aa1.1 slc30a1a slc30a1a zfand1 zfand1 p2rx5 p2rx5 slc30a4 slc30a4 hsp90aa1.2 hsp90aa1.2 glra4b glra4b pkd2 pkd2 LOC110439923 LOC110439923 mnat1 mnat1 gsk3ba gsk3ba glra4a glra4a cpne8 cpne8 bnip4 bnip4 ryr1b ryr1b slc25a24 slc25a24 slc39a10 slc39a10 slc26a5 slc26a5 aqp1a.1 aqp1a.1 zgc:73226 zgc:73226 entpd6 entpd6 crhbp crhbp oser1 oser1 mapk1 mapk1 p2rx8 p2rx8 prdx2 prdx2 prdx3 prdx3 syt4 syt4 casp9 casp9 glra1 glra1 syt9b syt9b slc30a2 slc30a2 ncf1 ncf1 ccl19a.2 ccl19a.2 eef2k eef2k E7FCW4_DANRE E7FCW4_DANRE gss gss atp7a atp7a stk25b stk25b fibina fibina cldn1 cldn1 hvcn1 hvcn1 rad51 rad51 mt2 mt2 p2rx7 p2rx7 cryaba cryaba sod2 sod2 nfe2l2a nfe2l2a itpka itpka jun jun sod1 sod1 sumo1 sumo1 atf1 atf1 slc30a5 slc30a5 gsk3bb gsk3bb F1QPV9_DANRE F1QPV9_DANRE creb1a creb1a LOC100002134 LOC100002134 alox5ap alox5ap badb badb ube3a ube3a syt11b syt11b F1QST3_DANRE F1QST3_DANRE slc40a1 slc40a1 cpne2 cpne2 syt11a syt11a prdx1 prdx1 ect2 ect2 ogg1 ogg1 stk26 stk26 prkaa1 prkaa1 prkaa2 prkaa2 syt17 syt17 trpc1 trpc1 adcy8 adcy8 atp13a2 atp13a2 adnpa adnpa cpox cpox phex phex E7EY50_DANRE E7EY50_DANRE syt9a syt9a pcsk1 pcsk1 foxa3 foxa3 chp2 chp2 pdcd6 pdcd6 gsk3ab gsk3ab abcb6a abcb6a COX1 COX1 rasa4 rasa4 jund jund sirt1 sirt1 slc39a6 slc39a6 fancc fancc mef2ca mef2ca ccl19a.1 ccl19a.1 adcy1a adcy1a atp6v0d1 atp6v0d1 dnmt3aa dnmt3aa syt1b syt1b tat tat sod3a sod3a alg2 alg2 cpne1 cpne1 mapk3 mapk3 slc30a1b slc30a1b nt5e nt5e edn1 edn1 khk khk uros uros glra2 glra2 trpa1b trpa1b sod3b sod3b mapk9 mapk9 timeless timeless syt6a syt6a txnrd2.2 txnrd2.2 adnpb adnpb nfatc4 nfatc4 daxx daxx slc25a24l slc25a24l atrx atrx nfe2l2b nfe2l2b cyp1b1 cyp1b1 adcy1b adcy1b p2rx4a p2rx4a dnmt3ba dnmt3ba junba junba aqp1a.2 aqp1a.2 bada bada ripk3 ripk3 ednrba ednrba crema crema
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gsk3aaGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (462 aa)
fosbFBJ murine osteosarcoma viral oncogene homolog B. (411 aa)
Q5RHR2_DANREAdenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1187 aa)
plekha1bPleckstrin homology domain-containing, family A (phosphoinositide-binding-specific) member 1b. (401 aa)
ccl19bChemokine (C-C motif) ligand 19b. (128 aa)
catCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family. (526 aa)
ryr2bRyanodine receptor 2b (cardiac). (4878 aa)
gphnbGephyrin2 isoform. (796 aa)
lonp1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (966 aa)
pamPeptidylglycine alpha-amidating monooxygenase. (1017 aa)
stk24bSerine/threonine kinase 24b (STE20 homolog, yeast). (432 aa)
slc25a12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (682 aa)
juneJunE proto-oncogene, AP-1 transcription factor subunit. (323 aa)
gphnaGephyrin a. (868 aa)
cpne9Copine family member IX. (543 aa)
syt7bSynaptotagmin VIIb. (488 aa)
B8JJU9_DANRESi:dkey-206d17.12. (626 aa)
guca1eGuanylate cyclase activator 1e. (198 aa)
ENSDARP00000136668Ncstrn_small domain-containing protein. (599 aa)
glrx2Glutaredoxin 2. (170 aa)
atrxlATRX chromatin remodeler,-like. (1760 aa)
cygb1Cytoglobin-1; May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. (174 aa)
cpne4aCopine IVa. (553 aa)
mef2cbMyocyte enhancer factor 2cb. (483 aa)
mtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1263 aa)
cyp1c1Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (523 aa)
homer1bHomer scaffold protein 1b. (398 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1037 aa)
zgc:153993Zgc:153993 protein. (204 aa)
bnip3BCL2-interacting protein 3. (183 aa)
cpne3Copine III. (532 aa)
cpne4bCopine IVb. (553 aa)
syt12Similar to synaptotagmin XII. (420 aa)
cpne7Copine VII. (559 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (458 aa)
syt1aSynaptotagmin Ia. (419 aa)
kdm6baLysine (K)-specific demethylase 6B, a. (1996 aa)
ENSDARP00000142835Si:dkey-23i12.7. (158 aa)
cpne5bCopine Vb. (574 aa)
adamts13ADAM metallopeptidase with thrombospondin type 1 motif, 13. (1498 aa)
ankzf1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (723 aa)
ENSDARP00000147747C2 domain-containing protein. (116 aa)
lgmnLegumain. (438 aa)
park7Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...] (189 aa)
ENSDARP00000150504Si:zfos-169g10.3. (72 aa)
impactProtein IMPACT; Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. Plays a role in differentiation of neuronal cells by stimulating neurite outgrowth. (317 aa)
blmBLM RecQ-like helicase. (1439 aa)
ENSDARP00000153250B30.2/SPRY domain-containing protein. (313 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
syt15Synaptotagmin XV. (420 aa)
LOC101884989C2 domain-containing protein. (368 aa)
CPNE8Copine 8. (576 aa)
syt6bSynaptotagmin VIb. (441 aa)
mtf1Metal-regulatory transcription factor 1. (774 aa)
RYR2Uncharacterized protein. (4478 aa)
fxnFrataxin. (200 aa)
mef2aaMyocyte enhancer factor 2aa. (458 aa)
ENSDARP00000117118Thioredoxin reductase 2, tandem duplicate 1. (206 aa)
cpne5aCopine Va. (563 aa)
selenow1Selenoprotein W; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity); Belongs to the SelWTH family. Selenoprotein W subfamily. (88 aa)
itpkcbKinase; Belongs to the inositol phosphokinase (IPK) family. (474 aa)
selenow2bSelenoprotein W, 2b. (94 aa)
dnmt3bb.3DNA (cytosine-5-)-methyltransferase beta, duplicate b.3; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1296 aa)
carfCalcium-responsive transcription factor. (661 aa)
pkd2l1Polycystic kidney disease 2-like 1. (790 aa)
ercc6Excision repair cross-complementation group 6. (1389 aa)
trpa1aTransient receptor potential cation channel, subfamily A, member 1a. (1126 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1080 aa)
itpkcaKinase; Belongs to the inositol phosphokinase (IPK) family. (417 aa)
A2BIG0_DANRETransporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (612 aa)
selenomSelenoprotein M; May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation; Belongs to the selenoprotein M/F family. (151 aa)
aifm1Apoptosis-inducing factor mitochondrion-associated 1. (750 aa)
ccsCopper chaperone for superoxide dismutase. (267 aa)
ryr1aRyanodine receptor 1a (skeletal). (5062 aa)
fosl1aFOS-like 1, AP-1 transcription factor subunit a. (346 aa)
glra3Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
kdm6bbLysine (K)-specific demethylase 6B, b. (1719 aa)
zgc:63972Protein CutA homolog. (167 aa)
bcl2aB-cell leukemia/lymphoma 2. (228 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1099 aa)
F1QB29_DANRETransporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (590 aa)
syt2aSynaptotagmin IIa. (430 aa)
fosl1bFOS-like 1, AP-1 transcription factor subunit b. (200 aa)
syt5aSynaptotagmin Va. (410 aa)
selenow2aSelenoprotein W, 2a. (95 aa)
itpkbKinase; Belongs to the inositol phosphokinase (IPK) family. (657 aa)
abcb6bATP-binding cassette, sub-family B (MDR/TAP), member 6b. (627 aa)
syt10Synaptotagmin X. (611 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (756 aa)
stk25aSerine/threonine kinase 25a. (421 aa)
zc3h12aZinc finger CCCH-type-containing 12A. (367 aa)
znf277Zinc finger protein 277. (440 aa)
smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (675 aa)
ednrbbEndothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (365 aa)
setxSenataxin. (2368 aa)
bcl2bBCL2 apoptosis regulator b. (209 aa)
syt3Synaptotagmin III. (566 aa)
atp7bATPase copper-transporting beta. (1363 aa)
syt7aSynaptotagmin VIIa. (607 aa)
ddi2Protein DDI1 homolog 2; Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1. Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required for cellular survival following replication stress. Belongs to the DDI1 family. (411 aa)
E7FC63_DANREAdenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1183 aa)
ryr3Ryanodine receptor 3. (4987 aa)
stk24aSerine/threonine kinase 24a (STE20 homolog, yeast). (415 aa)
junbbJunB proto-oncogene, AP-1 transcription factor subunit b. (310 aa)
slc25a13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (664 aa)
creb1bcAMP-responsive element-binding protein 1b. (324 aa)
ENSDARP00000132536Si:ch211-103a14.5. (199 aa)
slc30a10Solute carrier family 30 member 10. (385 aa)
slc30a8Solute carrier family 30 member 8. (388 aa)
plekha1aPleckstrin homology domain-containing, family A (phosphoinositide-binding-specific) member 1a. (401 aa)
smpd3Sphingomyelin phosphodiesterase 3. (684 aa)
syt5bSynaptotagmin Vb. (446 aa)
syt13Synaptotagmin XIII. (420 aa)
ripk1lReceptor (TNFRSF)-interacting serine-threonine kinase 1,-like. (661 aa)
pink1PTEN-induced kinase 1. (574 aa)
kcnmb2Potassium large conductance calcium-activated channel, subfamily M, beta member 2. (232 aa)
fgbFibrinogen, B beta polypeptide. (485 aa)
E7FF92_DANREC2 domain-containing protein. (258 aa)
gclcGlutamate-cysteine ligase, catalytic subunit. (631 aa)
bsgBasigin. (404 aa)
guca1aGuanylate cyclase activator 1A. (189 aa)
adgrv1Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system. (6198 aa)
hsp90aa1.1Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] (725 aa)
slc30a1aSolute carrier family 30 (Zinc transporter), member 1. (498 aa)
zfand1Zinc finger, AN1-type domain 1. (270 aa)
p2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (480 aa)
slc30a4Solute carrier family 30 (Zinc transporter), member 4. (345 aa)
hsp90aa1.2Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (734 aa)
glra4bGlycine receptor, alpha 4b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (537 aa)
pkd2Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel (By similarity). Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades. May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By simila [...] (904 aa)
LOC110439923Copper chaperone for superoxide dismutase. (267 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
gsk3baGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
glra4aGlycine receptor, alpha 4a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
cpne8Copine VIII. (575 aa)
bnip4BCL2-interacting protein 4. (177 aa)
ryr1bRyanodine receptor 1b (skeletal). (5078 aa)
slc25a24Calcium-binding mitochondrial carrier protein SCaMC-1; Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation of calcium-phosphate precipitates in the mitoc [...] (477 aa)
slc39a10Zinc transporter ZIP10; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. (847 aa)
slc26a5Solute carrier family 26, member 5. (739 aa)
aqp1a.1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (260 aa)
zgc:73226Zgc:73226. (187 aa)
entpd6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (442 aa)
crhbpCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (321 aa)
oser1Oxidative stress-responsive serine-rich 1. (300 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
p2rx8P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
prdx2Peroxiredoxin 2. (197 aa)
prdx3Peroxiredoxin 3. (281 aa)
syt4Synaptotagmin IV. (439 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (436 aa)
glra1Glycine receptor subunit alphaZ1; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol (By similarity); Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily. (459 aa)
syt9bSynaptotagmin IXb. (517 aa)
slc30a2Solute carrier family 30 member 2. (398 aa)
ncf1Neutrophil cytosolic factor 1. (410 aa)
ccl19a.2Chemokine (C-C motif) ligand 19a, tandem duplicate 2. (107 aa)
eef2kEukaryotic elongation factor 2 kinase. (706 aa)
E7FCW4_DANRESi:ch211-247n2.1. (261 aa)
gssGlutathione synthetase. (475 aa)
atp7aATPase copper-transporting alpha. (1500 aa)
stk25bSerine/threonine kinase 25 (STE20 homolog, yeast). (424 aa)
fibinaFin bud initiation factor a. (226 aa)
cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
hvcn1Voltage-gated hydrogen channel 1; Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient (By similarity). (235 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
mt2Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; Belongs to the metallothionein superfamily. Type 1 family. (60 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
cryabaCrystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family. (168 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
nfe2l2aNuclear factor (Erythroid-derived 2)-like 2. (586 aa)
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (448 aa)
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (308 aa)
sod1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
sumo1Small ubiquitin-related modifier 1; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i. This post- translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric sumo1 chains are also susceptible to polyubiquitination which functions as [...] (100 aa)
atf1Activating transcription factor 1. (304 aa)
slc30a5Zinc transporter 5; Functions as a zinc transporter. Partly regulates cellular zinc homeostasis (By similarity). (775 aa)
gsk3bbGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (419 aa)
F1QPV9_DANREKinase; Belongs to the inositol phosphokinase (IPK) family. (596 aa)
creb1acAMP-responsive element-binding protein 1a. (318 aa)
LOC100002134Uncharacterized protein. (462 aa)
alox5apArachidonate 5-lipoxygenase-activating protein. (156 aa)
badbBCL2-associated agonist of cell death b. (147 aa)
ube3aUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (857 aa)
syt11bSynaptotagmin XIb. (456 aa)
F1QST3_DANRESolute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (392 aa)
slc40a1Solute carrier family 40 member 1; May be involved in iron export and also in transfer of iron between maternal and fetal circulation. (562 aa)
cpne2Copine II. (563 aa)
syt11aSynaptotagmin XIa. (451 aa)
prdx1Peroxiredoxin 1. (199 aa)
ect2Epithelial cell-transforming 2. (976 aa)
ogg18-oxoguanine DNA glycosylase. (391 aa)
stk26Serine/threonine protein kinase 26. (412 aa)
prkaa1Non-specific serine/threonine protein kinase. (573 aa)
prkaa2Non-specific serine/threonine protein kinase. (553 aa)
syt17Synaptotagmin XVII. (474 aa)
trpc1Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (796 aa)
adcy8Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (892 aa)
atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1170 aa)
adnpaActivity-dependent neuroprotector homeobox a. (969 aa)
cpoxCoproporphyrinogen oxidase. (449 aa)
phexPhosphate-regulating endopeptidase homolog, X-linked. (745 aa)
E7EY50_DANRESi:ch211-38m6.7. (271 aa)
syt9aSynaptotagmin IXa. (547 aa)
pcsk1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (755 aa)
foxa3Forkhead box A3. (441 aa)
chp2Calcineurin-like EF-hand protein 2. (195 aa)
pdcd6Programmed cell death 6. (185 aa)
gsk3abGlycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
abcb6aATP-binding cassette, sub-family B (MDR/TAP), member 6a. (851 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (516 aa)
rasa4RAS p21 protein activator 4. (800 aa)
jundJunD proto-oncogene, AP-1 transcription factor subunit. (283 aa)
sirt1Sirtuin 1. (710 aa)
slc39a6Solute carrier family 39 member 6. (742 aa)
fanccFA complementation group C. (554 aa)
mef2caMyocyte enhancer factor 2ca. (465 aa)
ccl19a.1C-C motif chemokine. (119 aa)
adcy1aAdenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
atp6v0d1V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) p [...] (350 aa)
dnmt3aaDNA (cytosine-5-)-methyltransferase 3 alpha a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (852 aa)
syt1bNovel protein similar to vertebrate synaptotagmin I (SYT1). (388 aa)
tatTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (444 aa)
sod3aSuperoxide dismutase 3, extracellular a. (213 aa)
alg2ALG2 alpha-1,3/1,6-mannosyltransferase. (455 aa)
cpne1Copine I. (534 aa)
mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
slc30a1bSolute carrier family 30 member 1b. (475 aa)
nt5e5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. (571 aa)
edn1Endothelin 1. (188 aa)
khkKetohexokinase. (299 aa)
urosUroporphyrinogen III synthase. (262 aa)
glra2Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
trpa1bTransient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1120 aa)
sod3bSuperoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (192 aa)
mapk9Mitogen-activated protein kinase. (421 aa)
timelessTimeless circadian clock. (1278 aa)
syt6aSynaptotagmin VIa. (480 aa)
txnrd2.2Thioredoxin reductase 2, tandem duplicate 2. (515 aa)
adnpbActivity-dependent neuroprotector homeobox b. (1003 aa)
nfatc4Nuclear factor of-activated T cells 4. (865 aa)
daxxDeath-domain-associated protein. (716 aa)
slc25a24lSolute carrier family 25 member 24,-like; Belongs to the mitochondrial carrier (TC 2.A.29) family. (448 aa)
atrxATRX chromatin remodeler. (2013 aa)
nfe2l2bNuclear factor, erythroid 2-like 2b. (507 aa)
cyp1b1Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (526 aa)
adcy1bAdenylate cyclase 1b; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (834 aa)
p2rx4aP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (398 aa)
dnmt3baDNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1500 aa)
junbaJunB proto-oncogene, AP-1 transcription factor subunit a. (325 aa)
aqp1a.2Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
badaBCL2-associated agonist of cell death a. (145 aa)
ripk3Receptor-interacting serine-threonine kinase 3. (361 aa)
ednrbaEndothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (426 aa)
cremacAMP-responsive element modulator a. (110 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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