(16 nodes) Multicellular organism aging network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rnf165b	Ring finger protein 165b. (349 aa)
	ednrab	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (408 aa)
	gna13a	Guanine nucleotide-binding protein (G protein), alpha 13a. (376 aa)
	edn1	Endothelin 1. (188 aa)
	rnf165a	Ring finger protein 165a. (311 aa)
	LOC797518	Uncharacterized protein. (325 aa)
	gna12a	Guanine nucleotide-binding protein (G protein) alpha 12a. (385 aa)
	ercc1	Excision repair cross-complementing rodent repair deficiency, complementation group 1. (342 aa)
	gna13b	Guanine nucleotide-binding protein (G protein), alpha 13b. (377 aa)
	sec63	SEC63 homolog, protein translocation regulator. (751 aa)
	ednraa	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (422 aa)
	wrn	WRN RecQ-like helicase. (1436 aa)
	slc1a2b	Amino acid transporter. (564 aa)
	slc1a9	Amino acid transporter. (424 aa)
	slc1a2a	Amino acid transporter. (548 aa)
	ENSDARP00000147214	Uncharacterized protein. (129 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSDARP00000147214	LOC797518	ENSDARP00000147214	ENSDARP00000054786	Uncharacterized protein.	Uncharacterized protein.	0.775
ENSDARP00000147214	gna12a	ENSDARP00000147214	ENSDARP00000050331	Uncharacterized protein.	Guanine nucleotide-binding protein (G protein) alpha 12a.	0.557
ENSDARP00000147214	gna13a	ENSDARP00000147214	ENSDARP00000102226	Uncharacterized protein.	Guanine nucleotide-binding protein (G protein), alpha 13a.	0.563
ENSDARP00000147214	gna13b	ENSDARP00000147214	ENSDARP00000036006	Uncharacterized protein.	Guanine nucleotide-binding protein (G protein), alpha 13b.	0.563
LOC797518	ENSDARP00000147214	ENSDARP00000054786	ENSDARP00000147214	Uncharacterized protein.	Uncharacterized protein.	0.775
LOC797518	gna12a	ENSDARP00000054786	ENSDARP00000050331	Uncharacterized protein.	Guanine nucleotide-binding protein (G protein) alpha 12a.	0.560
LOC797518	gna13a	ENSDARP00000054786	ENSDARP00000102226	Uncharacterized protein.	Guanine nucleotide-binding protein (G protein), alpha 13a.	0.564
LOC797518	gna13b	ENSDARP00000054786	ENSDARP00000036006	Uncharacterized protein.	Guanine nucleotide-binding protein (G protein), alpha 13b.	0.570
edn1	ednraa	ENSDARP00000095917	ENSDARP00000002773	Endothelin 1.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.999
edn1	ednrab	ENSDARP00000095917	ENSDARP00000124118	Endothelin 1.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.999
ednraa	edn1	ENSDARP00000002773	ENSDARP00000095917	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.999
ednraa	ednrab	ENSDARP00000002773	ENSDARP00000124118	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.904
ednraa	gna12a	ENSDARP00000002773	ENSDARP00000050331	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein (G protein) alpha 12a.	0.921
ednraa	gna13a	ENSDARP00000002773	ENSDARP00000102226	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein (G protein), alpha 13a.	0.921
ednraa	gna13b	ENSDARP00000002773	ENSDARP00000036006	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein (G protein), alpha 13b.	0.921
ednrab	edn1	ENSDARP00000124118	ENSDARP00000095917	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.999
ednrab	ednraa	ENSDARP00000124118	ENSDARP00000002773	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.904
ednrab	gna12a	ENSDARP00000124118	ENSDARP00000050331	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein (G protein) alpha 12a.	0.921
ednrab	gna13a	ENSDARP00000124118	ENSDARP00000102226	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein (G protein), alpha 13a.	0.921
ednrab	gna13b	ENSDARP00000124118	ENSDARP00000036006	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein (G protein), alpha 13b.	0.921

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