node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC569566 | fgfr1a | ENSDARP00000117523 | ENSDARP00000013742 | Fibroblast growth factor receptor 1b,-like. | Fibroblast growth factor receptor 1-A; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers [...] | 0.900 |
LOC569566 | fgfr1b | ENSDARP00000117523 | ENSDARP00000069743 | Fibroblast growth factor receptor 1b,-like. | Fibroblast growth factor receptor. | 0.900 |
LOC569566 | vegfaa | ENSDARP00000117523 | ENSDARP00000133415 | Fibroblast growth factor receptor 1b,-like. | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | 0.717 |
agtr1a | agtr1b | ENSDARP00000009604 | ENSDARP00000124668 | Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family. | Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. | 0.904 |
agtr1b | agtr1a | ENSDARP00000124668 | ENSDARP00000009604 | Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. | Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family. | 0.904 |
fgfr1a | LOC569566 | ENSDARP00000013742 | ENSDARP00000117523 | Fibroblast growth factor receptor 1-A; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers [...] | Fibroblast growth factor receptor 1b,-like. | 0.900 |
fgfr1a | fgfr1b | ENSDARP00000013742 | ENSDARP00000069743 | Fibroblast growth factor receptor 1-A; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers [...] | Fibroblast growth factor receptor. | 0.902 |
fgfr1a | vegfaa | ENSDARP00000013742 | ENSDARP00000133415 | Fibroblast growth factor receptor 1-A; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers [...] | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | 0.872 |
fgfr1b | LOC569566 | ENSDARP00000069743 | ENSDARP00000117523 | Fibroblast growth factor receptor. | Fibroblast growth factor receptor 1b,-like. | 0.900 |
fgfr1b | fgfr1a | ENSDARP00000069743 | ENSDARP00000013742 | Fibroblast growth factor receptor. | Fibroblast growth factor receptor 1-A; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers [...] | 0.902 |
fgfr1b | vegfaa | ENSDARP00000069743 | ENSDARP00000133415 | Fibroblast growth factor receptor. | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | 0.752 |
htr2aa | htr2b | ENSDARP00000112740 | ENSDARP00000147603 | 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. | 0.635 |
htr2b | htr2aa | ENSDARP00000147603 | ENSDARP00000112740 | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. | 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. | 0.635 |
vegfaa | LOC569566 | ENSDARP00000133415 | ENSDARP00000117523 | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | Fibroblast growth factor receptor 1b,-like. | 0.717 |
vegfaa | fgfr1a | ENSDARP00000133415 | ENSDARP00000013742 | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | Fibroblast growth factor receptor 1-A; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers [...] | 0.872 |
vegfaa | fgfr1b | ENSDARP00000133415 | ENSDARP00000069743 | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | Fibroblast growth factor receptor. | 0.752 |