STRINGSTRING
Ghitm Ghitm ambra1b ambra1b ep300b ep300b zdhhc6 zdhhc6 LOC100004321 LOC100004321 pla2g6 pla2g6 avp avp fam162a fam162a zgc:110130 zgc:110130 oma1 oma1 F1Q9U8_DANRE F1Q9U8_DANRE huwe1 huwe1 cfap70 cfap70 fxn fxn mief2 mief2 gsk3aa gsk3aa zgc:163080 zgc:163080 ddhd1a ddhd1a bada bada zmp:0000000991 zmp:0000000991 negaly6 negaly6 stox1 stox1 tmem135 tmem135 E7F2C3_DANRE E7F2C3_DANRE ralbp1 ralbp1 bcl2l11 bcl2l11 A2CEZ0_DANRE A2CEZ0_DANRE slc25a5 slc25a5 mllt11 mllt11 ambra1a ambra1a ppargc1a ppargc1a flcn flcn mief1 mief1 atp13a2 atp13a2 mul1b mul1b cidec cidec si:dkey-27b3.2 si:dkey-27b3.2 slc25a1a slc25a1a vat1 vat1 badb badb htt htt gsk3bb gsk3bb vdac1 vdac1 prelid1b prelid1b rhot2 rhot2 bmf2 bmf2 mff mff ssbp1 ssbp1 acaa2 acaa2 ddhd1b ddhd1b pgam5 pgam5 golph3 golph3 vps13d vps13d march5 march5 tspo tspo zgc:73226 zgc:73226 march5l march5l bnip3la bnip3la bnip4 bnip4 pdcd5 pdcd5 slc25a4 slc25a4 gsk3ba gsk3ba dcn dcn baxa baxa slc25a6 slc25a6 gclc gclc igf1 igf1 igf2a igf2a pisd pisd pink1 pink1 gsk3ab gsk3ab psmd10 psmd10 slc35f6 slc35f6 vps35 vps35 LOC100535423 LOC100535423 ly6m2 ly6m2 fbxo7 fbxo7 myo19 myo19 LOC103910030 LOC103910030 stox2b stox2b ly6m5 ly6m5 zgc:153993 zgc:153993 ep300a ep300a bnip3 bnip3 zgc:158343 zgc:158343 rhot1b rhot1b ENSDARP00000140607 ENSDARP00000140607 ly6m6 ly6m6 rhot1a rhot1a prkn prkn prelid1a prelid1a stoml2 stoml2 LOC110438015 LOC110438015 sirt7 sirt7 ENSDARP00000131021 ENSDARP00000131021
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GhitmUncharacterized protein. (157 aa)
ambra1bAutophagy/beclin-1 regulator 1b. (1360 aa)
ep300bE1A-binding protein p300 b. (2615 aa)
zdhhc6Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (412 aa)
LOC100004321BCL2-associated X, apoptosis regulator a. (197 aa)
pla2g6Phospholipase A2, group VI (cytosolic, calcium-independent). (824 aa)
avpArginine vasopressin; Belongs to the vasopressin/oxytocin family. (151 aa)
fam162aProtein FAM162B. (156 aa)
zgc:110130Mitochondrial fission factor homolog A; Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity); Belongs to the Tango11 family. (286 aa)
oma1Metalloendopeptidase OMA1, mitochondrial; Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of opa1 at S1 position, leading to opa1 inactivation and negative regulation of mitochondrial fusion. (510 aa)
F1Q9U8_DANRESi:dkey-102g19.3. (207 aa)
huwe1HECT, UBA and WWE domain-containing E3 ubiquitin protein ligase 1. (4474 aa)
cfap70Cilia and flagella-associated protein 70. (1050 aa)
fxnFrataxin. (200 aa)
mief2Mitochondrial elongation factor 2. (272 aa)
gsk3aaGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (462 aa)
zgc:163080Zgc:163080 protein. (99 aa)
ddhd1aDDHD domain-containing 1a. (825 aa)
badaBCL2-associated agonist of cell death a. (145 aa)
zmp:0000000991Zmp:0000000991. (1515 aa)
negaly6Neuromast-expressed gpi-anchored lymphocyte antigen 6. (211 aa)
stox1Zgc:174575 protein. (967 aa)
tmem135Transmembrane protein 135. (465 aa)
E7F2C3_DANRESi:ch211-120k19.1; Belongs to the peroxisomal membrane protein PXMP2/4 family. (231 aa)
ralbp1RalA-binding protein 1. (665 aa)
bcl2l11BCL2-like 11. (176 aa)
A2CEZ0_DANRESi:dkey-251i10.1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
slc25a5Solute carrier family 25 member 5 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
mllt11Protein AF1q; Cofactor for the transcription factor TCF7. May be involved in lymphoid development. (82 aa)
ambra1aActivating molecule in beclin-1-regulated autophagy. (1315 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (859 aa)
flcnFolliculin. (558 aa)
mief1Mitochondrial dynamics protein MID51; Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization (By similarity). (468 aa)
atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1170 aa)
mul1bMitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
cidecCell death-inducing DFFA-like effector c. (239 aa)
si:dkey-27b3.2Si:dkey-27b3.2. (294 aa)
slc25a1aTricarboxylate transport protein A, mitochondrial; Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate (By similarity). Required for proper neuromuscular junction formation. (359 aa)
vat1Synaptic vesicle membrane protein VAT-1 homolog. (484 aa)
badbBCL2-associated agonist of cell death b. (147 aa)
httHuntingtin. (3121 aa)
gsk3bbGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (419 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
prelid1bPRELI domain-containing 1b. (199 aa)
rhot2Mitochondrial Rho GTPase 2; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity). (617 aa)
bmf2BCL2-modifying factor 2. (226 aa)
mffMitochondrial fission factor homolog B; Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity); Belongs to the Tango11 family. (230 aa)
ssbp1Single-stranded DNA-binding protein 1. (146 aa)
acaa2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ddhd1bDDHD domain-containing 1b. (859 aa)
pgam5Serine/threonine-protein phosphatase PGAM5, mitochondrial; Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics (By similarity). May be a central mediator for programmed necrosis (By similarity); Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (289 aa)
golph3Golgi phosphoprotein 3. (295 aa)
vps13dVacuolar protein sorting 13 homolog D. (3956 aa)
march5E3 ubiquitin-protein ligase MARCH5. (281 aa)
tspoTranslocator protein. (162 aa)
zgc:73226Zgc:73226. (187 aa)
march5lE3 ubiquitin-protein ligase MARCHF5; Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. (289 aa)
bnip3laBCL2/adenovirus E1B interacting protein 3-like, 2. (233 aa)
bnip4BCL2-interacting protein 4. (177 aa)
pdcd5Programmed cell death 5. (128 aa)
slc25a4Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
gsk3baGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
dcnDecorin; May affect the rate of fibrils formation. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (373 aa)
baxaBCL2-associated X, apoptosis regulator a. (192 aa)
slc25a6Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
gclcGlutamate-cysteine ligase, catalytic subunit. (631 aa)
igf1Insulin-like growth factor 1b. (161 aa)
igf2aInsulin-like growth factor 2a. (197 aa)
pisdPhosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (426 aa)
pink1PTEN-induced kinase 1. (574 aa)
gsk3abGlycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
psmd10Proteasome 26S subunit, non-ATPase, 10. (226 aa)
slc35f6Solute carrier family 35 member F6; May play a role as a nucleotide-sugar transporter. (374 aa)
vps35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (831 aa)
LOC100535423Lymphocyte antigen 6 family member M3. (196 aa)
ly6m2Lymphocyte antigen 6 family member M2. (198 aa)
fbxo7F-box protein 7. (485 aa)
myo19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (573 aa)
LOC103910030Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (237 aa)
stox2bStorkhead box 2b. (856 aa)
ly6m5Lymphocyte antigen 6 family member M5. (171 aa)
zgc:153993Zgc:153993 protein. (204 aa)
ep300aE1A-binding protein p300 a. (2679 aa)
bnip3BCL2-interacting protein 3. (183 aa)
zgc:158343Zgc:158343. (208 aa)
rhot1bMitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (660 aa)
ENSDARP00000140607Si:dkeyp-72e1.7; Belongs to the peroxisomal membrane protein PXMP2/4 family. (199 aa)
ly6m6Lymphocyte antigen 6 family member M6. (200 aa)
rhot1aMitochondrial Rho GTPase 1-A; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity). (619 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (458 aa)
prelid1aPRELI domain-containing 1a. (210 aa)
stoml2Stomatin (EPB72)-like 2. (355 aa)
LOC110438015UPAR/Ly6 domain-containing protein. (203 aa)
sirt7Sirtuin 7. (405 aa)
ENSDARP00000131021Si:ch211-134a4.6. (200 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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