STRINGSTRING
ENSDARP00000130422 ENSDARP00000130422 lrp6 lrp6 ENSDARP00000142120 ENSDARP00000142120 ENSDARP00000142414 ENSDARP00000142414 RAMP3 RAMP3 ENSDARP00000155118 ENSDARP00000155118 reck reck nradd nradd rgmb rgmb rgma rgma hjv hjv ramp2 ramp2 RAMP1 RAMP1 ackr3b ackr3b cdon cdon ackr3a ackr3a boc boc F1RB21_DANRE F1RB21_DANRE cspg4 cspg4 lrp5 lrp5 ngfra ngfra si:dkey-10h3.3 si:dkey-10h3.3 F1Q776_DANRE F1Q776_DANRE LOC565947 LOC565947 F1QAN5_DANRE F1QAN5_DANRE cd4-1 cd4-1 Si:dkey-10h3.1 Si:dkey-10h3.1 F1QK03_DANRE F1QK03_DANRE rgmd rgmd ngfrb ngfrb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSDARP00000130422Si:ch73-193i22.1. (161 aa)
lrp6Low density lipoprotein receptor-related protein 6. (935 aa)
ENSDARP00000142120Si:cabz01036006.1. (863 aa)
ENSDARP00000142414Si:ch211-220f21.1. (1177 aa)
RAMP3Receptor activity modifying protein 3. (88 aa)
ENSDARP00000155118Uncharacterized protein. (350 aa)
reckReversion-inducing cysteine-rich protein with Kazal motifs; Functions together with adgra2 to enable brain endothelial cells to selectively respond to Wnt7 signals (wnt7a or wnt7b). Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation. Acts as a Wnt7-specific coactivator of canonical Wnt signaling by decoding Wnt ligands: acts by interacting specifically with the disordered linker region of Wnt7, thereby conferring ligand selectivity for Wnt7. Adgra2 is then required to deliver reck-bound Wnt7 to frizzled [...] (755 aa)
nraddNeurotrophin receptor-associated death domain. (413 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (436 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (449 aa)
hjvHemojuvelin BMP co-receptor. (410 aa)
ramp2Receptor (G protein-coupled) activity-modifying protein 2. (206 aa)
RAMP1Zgc:91818 protein. (145 aa)
ackr3bAtypical chemokine receptor 3b; Belongs to the G-protein coupled receptor 1 family. (362 aa)
cdonCell adhesion molecule-related/down-regulated by oncogenes. (1125 aa)
ackr3aAtypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (398 aa)
bocBOC cell adhesion-associated, oncogene-regulated. (1032 aa)
F1RB21_DANRESi:dkey-193c22.2. (2389 aa)
cspg4Chondroitin sulfate proteoglycan 4. (2305 aa)
lrp5Low density lipoprotein receptor-related protein 5. (1615 aa)
ngfraNerve growth factor receptor a (TNFR superfamily, member 16). (346 aa)
si:dkey-10h3.3Si:dkey-10h3.3. (646 aa)
F1Q776_DANRESi:ch211-165f21.2. (986 aa)
LOC565947Si:dkey-10h3.2. (883 aa)
F1QAN5_DANRESi:ch73-334d15.2. (128 aa)
cd4-1CD4-1 molecule. (474 aa)
Si:dkey-10h3.1Si:ch211-165f21.2. (784 aa)
F1QK03_DANRESi:dkeyp-41f9.3. (1041 aa)
rgmdRGM domain family, member D. (458 aa)
ngfrbNerve growth factor receptor b. (431 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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